dy506 Search Results


elisa kits  (R&D Systems)
95
R&D Systems elisa kits
<t>Citronellol</t> prevented production of pro-inflammatory factors in experimental animals. <t>ELISA</t> and western blotting were performed to analyze the effect of citronellol on pro-inflammatory markers in the midbrain of experimental animals. Administration of rotenone (2.5 mg/kg, i. p) for four weeks significantly enhanced secretion of pro-inflammatory cytokines such as IL-1β, IL-6, TNF-α and MMP-9. (a). Further, rotenone enhanced the expression of COX-2 and iNOS in midbrain of experimental animals (b). Quantitative evaluations of blots were done using ImageJ and their results were represented in histogram (c). However, administration of citronellol (25 mg/kg, oral) for four weeks significantly decreased the expression of pro-inflammatory factors. Data are represented as mean ± SD. ∗p < 0.05 compared to control, # p < 0.05 compared to rotenone alone treated group.
Elisa Kits, supplied by R&D Systems, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 95 stars, based on 1 article reviews
elisa kits - by Bioz Stars, 2026-03
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il 6 concentrations  (R&D Systems)
95
R&D Systems il 6 concentrations
uPARAP regulates endogenous SP-D levels in the injured lung and is decisive for mouse sensitivity toward bleomycin-induced lung injury. (A–C) Endogenous SP-D was determined in BALs collected from bleomycin-treated (A), LPS-treated (B), and unchallenged (C) WT and uPARAP-deficient littermate mice. BALs from bleomycin- and LPS-challenged mice were collected 14 d and 48 h after challenge, respectively. Data are presented as mean ± SD. (D and E) Percent loss of weight (D) and overall survival rate (E) of WT and uPARAP-deficient littermates during a period of 14 d following bleomycin-induced lung injury. n = 22–23. Data are presented as mean ± SEM (D). (F) Correlation between BAL concentrations of SP-D <t>and</t> <t>IL-6</t> after bleomycin challenge. A combined dataset of log 2 -transformed SP-D and IL-6 measurements ( n = 40) from WT and uPARAP-deficient mice was used to test for correlation (top). An unbiased K means cluster analysis with two clusters was then used to generate an SP-D“ low” /IL-6“ high” cluster and an SP-D“ high” /IL-6“ low” cluster, and the number of data points from WT and uPARAP-deficient mice associated with each cluster was determined (top and bottom). (G and H) IL-6 concentrations in BAL from bleomycin-challenged (G) and unchallenged (H) mice. The BAL SP-D and IL-6 concentrations were measured by sandwich ELISA. n = 18–22 (A and G), 13–16 (B), and 8 (C and H). The following statistical tests were used: two-tailed Student’s t test (A–C, G, and H), two-way ANOVA and Sidak’s multiple comparisons test (D), log-rank (Mantel-Cox) test (E), and Pearson correlation and χ 2 test (F).
Il 6 Concentrations, supplied by R&D Systems, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/il 6 concentrations/product/R&D Systems
Average 95 stars, based on 1 article reviews
il 6 concentrations - by Bioz Stars, 2026-03
95/100 stars
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Image Search Results


Citronellol prevented production of pro-inflammatory factors in experimental animals. ELISA and western blotting were performed to analyze the effect of citronellol on pro-inflammatory markers in the midbrain of experimental animals. Administration of rotenone (2.5 mg/kg, i. p) for four weeks significantly enhanced secretion of pro-inflammatory cytokines such as IL-1β, IL-6, TNF-α and MMP-9. (a). Further, rotenone enhanced the expression of COX-2 and iNOS in midbrain of experimental animals (b). Quantitative evaluations of blots were done using ImageJ and their results were represented in histogram (c). However, administration of citronellol (25 mg/kg, oral) for four weeks significantly decreased the expression of pro-inflammatory factors. Data are represented as mean ± SD. ∗p < 0.05 compared to control, # p < 0.05 compared to rotenone alone treated group.

Journal: Heliyon

Article Title: Effect of citronellol on oxidative stress, neuroinflammation and autophagy pathways in an in vivo model of Parkinson's disease

doi: 10.1016/j.heliyon.2022.e11434

Figure Lengend Snippet: Citronellol prevented production of pro-inflammatory factors in experimental animals. ELISA and western blotting were performed to analyze the effect of citronellol on pro-inflammatory markers in the midbrain of experimental animals. Administration of rotenone (2.5 mg/kg, i. p) for four weeks significantly enhanced secretion of pro-inflammatory cytokines such as IL-1β, IL-6, TNF-α and MMP-9. (a). Further, rotenone enhanced the expression of COX-2 and iNOS in midbrain of experimental animals (b). Quantitative evaluations of blots were done using ImageJ and their results were represented in histogram (c). However, administration of citronellol (25 mg/kg, oral) for four weeks significantly decreased the expression of pro-inflammatory factors. Data are represented as mean ± SD. ∗p < 0.05 compared to control, # p < 0.05 compared to rotenone alone treated group.

Article Snippet: Anti-inflammatory activity of citronellol was analyzed using commercially available ELISA kits from R&D systems, Minnesota, United States (IL-6: Cat. No. DY506, TNF-α: Cat. No. DY510, IL-1β: Cat. No. DY501).

Techniques: Enzyme-linked Immunosorbent Assay, Western Blot, Expressing, Control

uPARAP regulates endogenous SP-D levels in the injured lung and is decisive for mouse sensitivity toward bleomycin-induced lung injury. (A–C) Endogenous SP-D was determined in BALs collected from bleomycin-treated (A), LPS-treated (B), and unchallenged (C) WT and uPARAP-deficient littermate mice. BALs from bleomycin- and LPS-challenged mice were collected 14 d and 48 h after challenge, respectively. Data are presented as mean ± SD. (D and E) Percent loss of weight (D) and overall survival rate (E) of WT and uPARAP-deficient littermates during a period of 14 d following bleomycin-induced lung injury. n = 22–23. Data are presented as mean ± SEM (D). (F) Correlation between BAL concentrations of SP-D and IL-6 after bleomycin challenge. A combined dataset of log 2 -transformed SP-D and IL-6 measurements ( n = 40) from WT and uPARAP-deficient mice was used to test for correlation (top). An unbiased K means cluster analysis with two clusters was then used to generate an SP-D“ low” /IL-6“ high” cluster and an SP-D“ high” /IL-6“ low” cluster, and the number of data points from WT and uPARAP-deficient mice associated with each cluster was determined (top and bottom). (G and H) IL-6 concentrations in BAL from bleomycin-challenged (G) and unchallenged (H) mice. The BAL SP-D and IL-6 concentrations were measured by sandwich ELISA. n = 18–22 (A and G), 13–16 (B), and 8 (C and H). The following statistical tests were used: two-tailed Student’s t test (A–C, G, and H), two-way ANOVA and Sidak’s multiple comparisons test (D), log-rank (Mantel-Cox) test (E), and Pearson correlation and χ 2 test (F).

Journal: The Journal of Cell Biology

Article Title: Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins

doi: 10.1083/jcb.201802148

Figure Lengend Snippet: uPARAP regulates endogenous SP-D levels in the injured lung and is decisive for mouse sensitivity toward bleomycin-induced lung injury. (A–C) Endogenous SP-D was determined in BALs collected from bleomycin-treated (A), LPS-treated (B), and unchallenged (C) WT and uPARAP-deficient littermate mice. BALs from bleomycin- and LPS-challenged mice were collected 14 d and 48 h after challenge, respectively. Data are presented as mean ± SD. (D and E) Percent loss of weight (D) and overall survival rate (E) of WT and uPARAP-deficient littermates during a period of 14 d following bleomycin-induced lung injury. n = 22–23. Data are presented as mean ± SEM (D). (F) Correlation between BAL concentrations of SP-D and IL-6 after bleomycin challenge. A combined dataset of log 2 -transformed SP-D and IL-6 measurements ( n = 40) from WT and uPARAP-deficient mice was used to test for correlation (top). An unbiased K means cluster analysis with two clusters was then used to generate an SP-D“ low” /IL-6“ high” cluster and an SP-D“ high” /IL-6“ low” cluster, and the number of data points from WT and uPARAP-deficient mice associated with each cluster was determined (top and bottom). (G and H) IL-6 concentrations in BAL from bleomycin-challenged (G) and unchallenged (H) mice. The BAL SP-D and IL-6 concentrations were measured by sandwich ELISA. n = 18–22 (A and G), 13–16 (B), and 8 (C and H). The following statistical tests were used: two-tailed Student’s t test (A–C, G, and H), two-way ANOVA and Sidak’s multiple comparisons test (D), log-rank (Mantel-Cox) test (E), and Pearson correlation and χ 2 test (F).

Article Snippet: IL-6 concentrations in BAL fluids were determined using a mouse IL-6 DuoSet ELISA (R&D Systems).

Techniques: Transformation Assay, Sandwich ELISA, Two Tailed Test