Journal: Scientific Reports

Article Title: Eco-friendly spectrophotometric quantification of the potential combination of mirabegron and tamsulosin

doi: 10.1038/s41598-025-06157-9

Figure Lengend Snippet: The chemical composition of ( a ) MIR and ( b ) TAM.

Article Snippet: Reference standards of TAM (99.75%) and MIR (99.88%) were procured from LGC Standards.

Techniques:

Journal: Scientific Reports

Article Title: Eco-friendly spectrophotometric quantification of the potential combination of mirabegron and tamsulosin

doi: 10.1038/s41598-025-06157-9

Figure Lengend Snippet: Spectra of zero order for MIR (10 µg/mL) and TAM (30 µg/mL).

Article Snippet: Reference standards of TAM (99.75%) and MIR (99.88%) were procured from LGC Standards.

Techniques:

Journal: Scientific Reports

Article Title: Eco-friendly spectrophotometric quantification of the potential combination of mirabegron and tamsulosin

doi: 10.1038/s41598-025-06157-9

Figure Lengend Snippet: ( a ) Zero absorption spectrum of 10 µg/mL MIR overlaid with 30 µg/mL TAM revealed that 240 nm and 266 nm has the same absorbance in TAM and ( b ) Zero absorption spectrum of 30 µg/mL TAM overlaid with 10 µg/mL MIR revealed that 230 nm and 262 nm has the same absorbance in MIR.

Article Snippet: Reference standards of TAM (99.75%) and MIR (99.88%) were procured from LGC Standards.

Techniques:

Journal: Scientific Reports

Article Title: Eco-friendly spectrophotometric quantification of the potential combination of mirabegron and tamsulosin

doi: 10.1038/s41598-025-06157-9

Figure Lengend Snippet: Spectra of the ratios of ( a ) MIR (3–20 µg/mL) utilizing 10 µg/mL of TAM as a divisor and ( b ) TAM (2–40 µg/mL) utilizing 7 µg/mL of MIR as a divisor.

Article Snippet: Reference standards of TAM (99.75%) and MIR (99.88%) were procured from LGC Standards.

Techniques:

Journal: Scientific Reports

Article Title: Eco-friendly spectrophotometric quantification of the potential combination of mirabegron and tamsulosin

doi: 10.1038/s41598-025-06157-9

Figure Lengend Snippet: First derivative of ratio spectra of ( a ) MIR (3–20 µg/mL) ( b ) TAM (2–40 µg/mL).

Article Snippet: Reference standards of TAM (99.75%) and MIR (99.88%) were procured from LGC Standards.

Techniques:

Journal: Drug testing and analysis

Article Title: Validation of the Only Commercially Available Immunoassay for Synthetic Cathinones in Urine: Randox Drugs of Abuse V Biochip Array Technology

doi: 10.1002/dta.1633

Figure Lengend Snippet: Mean %bias of the Randox DOA-V synthetic cathinone biochip A) BSI and B) BSII assays across their linear ranges using DOA-V original and new assays. Randox proposed cutoffs were 5 and 30µg/L for BSI and BSII. The vertical line (····) represents the manufacturer’s proposed cutoffs for original and new assays and (—) highest calibrators (grey: original assay, black: new assay). Horizontal lines represent (····) ±20% acceptance criteria.

Article Snippet: The Randox DOA-V Biochip Array Technology paired with the Randox Evidence ® Analyzer is capable of testing 90 samples for 11 different analytes in approximately one to two hours.

Techniques:

Journal: Drug testing and analysis

Article Title: Validation of the Only Commercially Available Immunoassay for Synthetic Cathinones in Urine: Randox Drugs of Abuse V Biochip Array Technology

doi: 10.1002/dta.1633

Figure Lengend Snippet: Randox DOA-V Biochip Immunoassay synthetic cathinone presumptive positive results for 20,017 screened urine specimens, and presumptive positive rates of synthetic cathinones (N=106). Presumptive positive urine specimens (N=97) confirmed by liquid chromatography high resolution tandem mass spectrometry (LC-HRMS).

Article Snippet: The Randox DOA-V Biochip Array Technology paired with the Randox Evidence ® Analyzer is capable of testing 90 samples for 11 different analytes in approximately one to two hours.

Techniques: Liquid Chromatography, Mass Spectrometry

Journal: Drug testing and analysis

Article Title: Validation of the Only Commercially Available Immunoassay for Synthetic Cathinones in Urine: Randox Drugs of Abuse V Biochip Array Technology

doi: 10.1002/dta.1633

Figure Lengend Snippet: Performance around cutoff concentrations of Randox synthetic cathinone BSI biochip for original and new DOA-V kits. Mephedrone fortified negative urine samples at cutoff A) 2.5, B) 5, C) 7.5, and D) 10µg/L, and ±25% and ±50% of cutoffs. Error bars represent ±2SD from mean observed concentration.

Article Snippet: The Randox DOA-V Biochip Array Technology paired with the Randox Evidence ® Analyzer is capable of testing 90 samples for 11 different analytes in approximately one to two hours.

Techniques: Concentration Assay

Journal: Drug testing and analysis

Article Title: Validation of the Only Commercially Available Immunoassay for Synthetic Cathinones in Urine: Randox Drugs of Abuse V Biochip Array Technology

doi: 10.1002/dta.1633

Figure Lengend Snippet: Performance around cutoff concentrations of Randox synthetic cathinone BSII biochip for original and new DOA-V assays. MDPV fortified negative urine samples at A) 20, B) 30, and C) 40µg/L cutoffs, and ±25% and ±50% of these cutoffs. Error bars represent ±2SD from the mean observed concentration.

Article Snippet: The Randox DOA-V Biochip Array Technology paired with the Randox Evidence ® Analyzer is capable of testing 90 samples for 11 different analytes in approximately one to two hours.

Techniques: Concentration Assay

Journal: Drug testing and analysis

Article Title: Validation of the Only Commercially Available Immunoassay for Synthetic Cathinones in Urine: Randox Drugs of Abuse V Biochip Array Technology

doi: 10.1002/dta.1633

Figure Lengend Snippet: Mean %bias of the Randox DOA-V synthetic cathinone biochip A) BSI and B) BSII assays across their linear ranges using DOA-V original and new assays. Randox proposed cutoffs were 5 and 30µg/L for BSI and BSII. The vertical line (····) represents the manufacturer’s proposed cutoffs for original and new assays and (—) highest calibrators (grey: original assay, black: new assay). Horizontal lines represent (····) ±20% acceptance criteria.

Article Snippet: The Randox DOA-V biochip array is currently the only immunoassay available for preliminary detection of synthetic cathinones in urine, and also is capable of high-throughput and requires only a small urine sample volume on the Evidence® Analyzer.

Techniques:

Journal: Drug testing and analysis

Article Title: Validation of the Only Commercially Available Immunoassay for Synthetic Cathinones in Urine: Randox Drugs of Abuse V Biochip Array Technology

doi: 10.1002/dta.1633

Figure Lengend Snippet: Intra-, inter-, and total imprecision for Randox synthetic cathinone antibodies, BSI and BSII, for both original and new DOA-V assays at three concentrations (BSI 1, 5, 15µg/L and BSII 30, 275, 555µg/L).

Article Snippet: The Randox DOA-V biochip array is currently the only immunoassay available for preliminary detection of synthetic cathinones in urine, and also is capable of high-throughput and requires only a small urine sample volume on the Evidence® Analyzer.

Techniques:

Journal: Drug testing and analysis

Article Title: Validation of the Only Commercially Available Immunoassay for Synthetic Cathinones in Urine: Randox Drugs of Abuse V Biochip Array Technology

doi: 10.1002/dta.1633

Figure Lengend Snippet: Randox DOA-V Biochip Immunoassay synthetic cathinone presumptive positive results for 20,017 screened urine specimens, and presumptive positive rates of synthetic cathinones (N=106). Presumptive positive urine specimens (N=97) confirmed by liquid chromatography high resolution tandem mass spectrometry (LC-HRMS).

Article Snippet: The Randox DOA-V biochip array is currently the only immunoassay available for preliminary detection of synthetic cathinones in urine, and also is capable of high-throughput and requires only a small urine sample volume on the Evidence® Analyzer.

Techniques: Liquid Chromatography, Mass Spectrometry

Journal: Drug testing and analysis

Article Title: Validation of the Only Commercially Available Immunoassay for Synthetic Cathinones in Urine: Randox Drugs of Abuse V Biochip Array Technology

doi: 10.1002/dta.1633

Figure Lengend Snippet: Performance around cutoff concentrations of Randox synthetic cathinone BSI biochip for original and new DOA-V kits. Mephedrone fortified negative urine samples at cutoff A) 2.5, B) 5, C) 7.5, and D) 10µg/L, and ±25% and ±50% of cutoffs. Error bars represent ±2SD from mean observed concentration.

Article Snippet: The Randox DOA-V biochip array is currently the only immunoassay available for preliminary detection of synthetic cathinones in urine, and also is capable of high-throughput and requires only a small urine sample volume on the Evidence® Analyzer.

Techniques: Concentration Assay

Journal: Drug testing and analysis

Article Title: Validation of the Only Commercially Available Immunoassay for Synthetic Cathinones in Urine: Randox Drugs of Abuse V Biochip Array Technology

doi: 10.1002/dta.1633

Figure Lengend Snippet: Performance around cutoff concentrations of Randox synthetic cathinone BSII biochip for original and new DOA-V assays. MDPV fortified negative urine samples at A) 20, B) 30, and C) 40µg/L cutoffs, and ±25% and ±50% of these cutoffs. Error bars represent ±2SD from the mean observed concentration.

Article Snippet: The Randox DOA-V biochip array is currently the only immunoassay available for preliminary detection of synthetic cathinones in urine, and also is capable of high-throughput and requires only a small urine sample volume on the Evidence® Analyzer.

Techniques: Concentration Assay