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MathWorks Inc doublegeneko
Comparison of the time cost of metabolic modeling between FastMM and other software using Gurobi solver
Doublegeneko, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Comparison of the time cost of metabolic modeling between FastMM and other software using Gurobi solver

Journal: BMC Bioinformatics

Article Title: FastMM: an efficient toolbox for personalized constraint-based metabolic modeling

doi: 10.1186/s12859-020-3410-4

Figure Lengend Snippet: Comparison of the time cost of metabolic modeling between FastMM and other software using Gurobi solver

Article Snippet: Because the program “doubleGeneKO” contains both single and double gene knockout results, we can implement single and double gene knockout analysis by the following Matlab interface function using 8 threading: > > GeneKOout = FastMM_doubleGeneKO_multi(consmodel, rxnsmatrix, 8) The results suggested that PEPD, SLC15A1, and SLC5A3 were candidates for individual lethal genes specific to lung cancer, and pairs of CBS-SLC7A11, CBS-SLC3A2, CMPK1-PTDSS1, CMPK1-PLD2 were candidate synergistic lethal genes specific in the tumors.

Techniques: Comparison, Software, Combined Bisulfite Restriction Analysis Assay