Journal: Heliyon

Article Title: Recent advances in the control of dengue fever using herbal and synthetic drugs

doi: 10.1016/j.heliyon.2025.e41939

Figure Lengend Snippet: Chemical Structures of various medications used to targeting DENV (Created by the authors with assistance from PubChem and medchemexpress.com ).

Article Snippet: Chemical Structures of various medications used to targeting DENV (Created by the authors with assistance from PubChem and medchemexpress.com ).

Techniques: Medications

Journal: Emerging Microbes & Infections

Article Title: Multiple introductions of highly pathogenic avian influenza H5N1 viruses into Bangladesh

doi: 10.1038/emi.2014.11

Figure Lengend Snippet: Avian influenza A (H5N1) virus isolates from live bird markets in Bangladesh from December 2010 to March 2013

Article Snippet: Within the HA phylogenetic tree, isolates A/Ck/BD/15079/12 (H5N1) and A/Ck/BD/15083/12 (H5N1), both original samples collected on the same day in January 2012 from the same live bird market in Dhaka city, fell within clade 2.3.2.1, but did not cluster together with the rest of the H5N1 isolates from Bangladesh.

Techniques: Virus, Isolation

Journal: Emerging Microbes & Infections

Article Title: Multiple introductions of highly pathogenic avian influenza H5N1 viruses into Bangladesh

doi: 10.1038/emi.2014.11

Figure Lengend Snippet: Antigenic analysis of H5N1 influenza viruses from Bangladesh in the hemagglutination inhibition assays

Article Snippet: Within the HA phylogenetic tree, isolates A/Ck/BD/15079/12 (H5N1) and A/Ck/BD/15083/12 (H5N1), both original samples collected on the same day in January 2012 from the same live bird market in Dhaka city, fell within clade 2.3.2.1, but did not cluster together with the rest of the H5N1 isolates from Bangladesh.

Techniques: HI Assay

Journal: Emerging Microbes & Infections

Article Title: Multiple introductions of highly pathogenic avian influenza H5N1 viruses into Bangladesh

doi: 10.1038/emi.2014.11

Figure Lengend Snippet: Amino-acid residues characteristic of the H5N1 viruses isolated from Bangladesh

Article Snippet: Within the HA phylogenetic tree, isolates A/Ck/BD/15079/12 (H5N1) and A/Ck/BD/15083/12 (H5N1), both original samples collected on the same day in January 2012 from the same live bird market in Dhaka city, fell within clade 2.3.2.1, but did not cluster together with the rest of the H5N1 isolates from Bangladesh.

Techniques: Isolation, Residue, Virus, Binding Assay, Infection, Marker

Journal: Emerging Microbes & Infections

Article Title: Multiple introductions of highly pathogenic avian influenza H5N1 viruses into Bangladesh

doi: 10.1038/emi.2014.11

Figure Lengend Snippet: Phylogenetic tree of the HA genes of HPAI H5N1 viruses from Bangladesh, generated by neighbor-joining method in MEGA 5. Numbers at the branches indicate bootstrap values; only values >70 are shown. ▴ indicates Bangladesh isolates clade 2.2.2; ▪ indicates Bangladesh isolates from the A/Hubei/1/10-like lineage of clade 2.3.2.1; • indicates Bangladesh isolates from the A/Hong Kong/6841/10-like lineage of clade 2.3.2.1.

Article Snippet: Within the HA phylogenetic tree, isolates A/Ck/BD/15079/12 (H5N1) and A/Ck/BD/15083/12 (H5N1), both original samples collected on the same day in January 2012 from the same live bird market in Dhaka city, fell within clade 2.3.2.1, but did not cluster together with the rest of the H5N1 isolates from Bangladesh.

Techniques: Generated

Journal: Emerging Microbes & Infections

Article Title: Multiple introductions of highly pathogenic avian influenza H5N1 viruses into Bangladesh

doi: 10.1038/emi.2014.11

Figure Lengend Snippet: Phylogenetic tree of the NA gene of H5N1 viruses from Bangladesh, generated by neighbor-joining method in MEGA 5. Numbers at the branches indicate bootstrap values; only values >70 are shown. ▴ indicates Bangladesh isolates clade 2.2.2; ▪ indicates Bangladesh isolates from the A/Hubei/1/10-like lineage of clade 2.3.2.1; • indicates Bangladesh isolates from the A/Hong Kong/6841/10-like lineage of clade 2.3.2.1.

Article Snippet: Within the HA phylogenetic tree, isolates A/Ck/BD/15079/12 (H5N1) and A/Ck/BD/15083/12 (H5N1), both original samples collected on the same day in January 2012 from the same live bird market in Dhaka city, fell within clade 2.3.2.1, but did not cluster together with the rest of the H5N1 isolates from Bangladesh.

Techniques: Generated

Journal: Emerging Microbes & Infections

Article Title: Multiple introductions of highly pathogenic avian influenza H5N1 viruses into Bangladesh

doi: 10.1038/emi.2014.11

Figure Lengend Snippet: Phylogenetic tree of the M gene of H5N1 viruses from Bangladesh, generated by neighbor-joining method in MEGA 5. Numbers at the branches indicate bootstrap values; only values >70 are shown. ▴ indicates Bangladesh isolates clade 2.2.2; ▪ indicates Bangladesh isolates from the A/Hubei/1/10-like lineage of clade 2.3.2.1; • indicates Bangladesh isolates from the A/Hong Kong/6841/10-like lineage of clade 2.3.2.1.

Article Snippet: Within the HA phylogenetic tree, isolates A/Ck/BD/15079/12 (H5N1) and A/Ck/BD/15083/12 (H5N1), both original samples collected on the same day in January 2012 from the same live bird market in Dhaka city, fell within clade 2.3.2.1, but did not cluster together with the rest of the H5N1 isolates from Bangladesh.

Techniques: Generated

Journal: Emerging Microbes & Infections

Article Title: Multiple introductions of highly pathogenic avian influenza H5N1 viruses into Bangladesh

doi: 10.1038/emi.2014.11

Figure Lengend Snippet: Phylogenetic tree of the PB2 gene of H5N1 viruses from Bangladesh, generated by neighbor-joining method in MEGA 5. Numbers at the branches indicate bootstrap values; only values >70 are shown. ▴ indicates Bangladesh isolates clade 2.2.2; ▪ indicates Bangladesh isolates from the A/Hubei/1/10-like lineage of clade 2.3.2.1; • indicates Bangladesh isolates from the A/Hong Kong/6841/10-like lineage of clade 2.3.2.1.

Article Snippet: Within the HA phylogenetic tree, isolates A/Ck/BD/15079/12 (H5N1) and A/Ck/BD/15083/12 (H5N1), both original samples collected on the same day in January 2012 from the same live bird market in Dhaka city, fell within clade 2.3.2.1, but did not cluster together with the rest of the H5N1 isolates from Bangladesh.

Techniques: Generated

Journal: Frontiers in Chemistry

Article Title: Identification of 6ω-cyclohexyl-2-(phenylamino carbonylmethylthio)pyrimidin-4(3 H )-ones targeting the ZIKV NS5 RNA dependent RNA polymerase

doi: 10.3389/fchem.2022.1010547

Figure Lengend Snippet: The interaction between 4w and ZIKV NS5 protein. (A) WB detection of ZIKV NS5 protein expression under different temperature gradients after 4w treatment; (B) NS5 protein grayscale analysis and ZIKV NS5 protein expression after 4w treatment observed changes in aggregation temperature; data is the mean (±SD) of three experiments. * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001.

Article Snippet: Subsequently, the protein was transferred to a polyvinylidene fluoride (PVDF) membrane and incubated with ZIKV E (1:2,000) and NS5 antibody (1:2,000) overnight at 4°C (Sino Biological, China) then add the corresponding secondary antibody and incubate at room temperature for 2 h. A specific signal was presented with a chemiluminescent substrate.

Techniques: Expressing

Journal: Frontiers in Chemistry

Article Title: Identification of 6ω-cyclohexyl-2-(phenylamino carbonylmethylthio)pyrimidin-4(3 H )-ones targeting the ZIKV NS5 RNA dependent RNA polymerase

doi: 10.3389/fchem.2022.1010547

Figure Lengend Snippet: Compound 4w inhibited the expression of ZIKV E and NS5 protein. (A) Western blot detected the inhibitory effect of 4w on ZIKV E and NS5 protein under the concentration gradient of 4w ; (B) Grayscale analysis and statistics of the inhibition of 4w on ZIKV E and NS5 protein under the concentration gradient of WB detection; Data is the mean (±SD) of three experiments, with DMSO as a positive contro * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001. (C) Detected the inhibitory effect of 4w on ZIKV E protein by immunofluorescence.

Article Snippet: Subsequently, the protein was transferred to a polyvinylidene fluoride (PVDF) membrane and incubated with ZIKV E (1:2,000) and NS5 antibody (1:2,000) overnight at 4°C (Sino Biological, China) then add the corresponding secondary antibody and incubate at room temperature for 2 h. A specific signal was presented with a chemiluminescent substrate.

Techniques: Expressing, Western Blot, Concentration Assay, Inhibition, Immunofluorescence