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Image Search Results
Journal: PLoS ONE
Article Title: A Complex Role of Herpes Viruses in the Disease Process of Multiple Sclerosis
doi: 10.1371/journal.pone.0105434
Figure Lengend Snippet: Intracellular cytokine secretion of each research subject was analyzed for IFN-γ + , TNF-α + and double positive T cell events. The sums of all cytokine positive events were normalized to beads. Ratios of intrathecal to peripheral T cell reactivities of un-treated (RR) and DAC HYP-treated RRMS patients (Dac) were calculated to foreign Ag's for CD4 + ( A ) and CD8 + T cells ( B ). Ratios greater than one (dotted line) indicate enrichment of Ag-specific T cell events in the intrathecal compartment; ratios lower than one represent less pronounced intrathecal T cell responses. Horizontal bars represent median values; vertical lines represent interquartile ranges. *0.01
Article Snippet: In addition to the un-treated RRMS cohort, 19 RRMS patients received long-term treatment (>36 months) with
Techniques: