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Image Search Results
Journal: Cell systems
Article Title: Inferring leading interactions in the p53/Mdm2/Mdmx circuit through live-cell imaging and modeling
doi: 10.1016/j.cels.2019.10.010
Figure Lengend Snippet: A) Schematic diagram of the Mdm2-Mdmx -p53 network. Mdmx inhibits the p53-Mdm2 oscillator through two arms: degradation of p53 through catalyzing Mdm2-mediated ubiquitination (blue left arm) and inhibition of p53 transcriptional activity (orange right arm).
Article Snippet: table ft1 table-wrap mode="anchored" t5 caption a7 REAGENT or
Techniques: Inhibition, Activity Assay
Journal: Cell systems
Article Title: Inferring leading interactions in the p53/Mdm2/Mdmx circuit through live-cell imaging and modeling
doi: 10.1016/j.cels.2019.10.010
Figure Lengend Snippet: A) Schematics of the p53-Mdm2 negative feedback loop with the parameters (β, γ, Ψ, TDel) in our mathematical model.
Article Snippet: table ft1 table-wrap mode="anchored" t5 caption a7 REAGENT or
Techniques:
Journal: Cell systems
Article Title: Inferring leading interactions in the p53/Mdm2/Mdmx circuit through live-cell imaging and modeling
doi: 10.1016/j.cels.2019.10.010
Figure Lengend Snippet: A) Schematic of the p53-Mdm2 system with regulation by Mdmx and ATR. ATR can inhibit Mdm2-mediated p53 degradation through two impact factors (κ2 or κ2)
Article Snippet: table ft1 table-wrap mode="anchored" t5 caption a7 REAGENT or
Techniques:
Journal: Cell systems
Article Title: Inferring leading interactions in the p53/Mdm2/Mdmx circuit through live-cell imaging and modeling
doi: 10.1016/j.cels.2019.10.010
Figure Lengend Snippet: Key Resource Table
Article Snippet: table ft1 table-wrap mode="anchored" t5 caption a7 REAGENT or
Techniques: Negative Control, Software, Single Cell Tracking