crispra sgrna libraries Search Results


sgrna crispra library  (Broad Institute Inc)
90
Broad Institute Inc sgrna crispra library
( A ) THP-1 cells were stained for intracellular TNF-α and sorted into TNF-α + , TNF-α – , TNF-α hi , and TNF-α lo populations. Enrichment and depletion of sgRNAs in TNF-α subpopulations were compared with presorted and TNF-α – populations. ( B ) Log fold-change of sgRNAs targeting the TSS of TNFA reveal correlation with TNF-α levels, thus validating the <t>CRISPRa</t> screening potential. ( C – F ) Log fold-change of sgRNAs targeting lncRNAs that positively ( lnc-MAP3K11-1 , C ) or negatively ( lnc-IL5-1 , D ; SENCR , E ; lncTMEM154-4 , F ) correlate with levels of TNF-α production.
Sgrna Crispra Library, supplied by Broad Institute Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/crispra+sgrna+libraries/pmc10967393-303-1-10?v=Broad+Institute+Inc
Average 90 stars, based on 1 article reviews
sgrna crispra library - by Bioz Stars, 2026-07
90/100 stars
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hif2 subpool crispra sgrna library  (Broad Institute Inc)
90
Broad Institute Inc hif2 subpool crispra sgrna library
( A ) THP-1 cells were stained for intracellular TNF-α and sorted into TNF-α + , TNF-α – , TNF-α hi , and TNF-α lo populations. Enrichment and depletion of sgRNAs in TNF-α subpopulations were compared with presorted and TNF-α – populations. ( B ) Log fold-change of sgRNAs targeting the TSS of TNFA reveal correlation with TNF-α levels, thus validating the <t>CRISPRa</t> screening potential. ( C – F ) Log fold-change of sgRNAs targeting lncRNAs that positively ( lnc-MAP3K11-1 , C ) or negatively ( lnc-IL5-1 , D ; SENCR , E ; lncTMEM154-4 , F ) correlate with levels of TNF-α production.
Hif2 Subpool Crispra Sgrna Library, supplied by Broad Institute Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/crispra+sgrna+libraries/10__1158_slash_2159___8290__cd___24___1378-162-1-19?v=Broad+Institute+Inc
Average 90 stars, based on 1 article reviews
hif2 subpool crispra sgrna library - by Bioz Stars, 2026-07
90/100 stars
  Buy from Supplier

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( A ) THP-1 cells were stained for intracellular TNF-α and sorted into TNF-α + , TNF-α – , TNF-α hi , and TNF-α lo populations. Enrichment and depletion of sgRNAs in TNF-α subpopulations were compared with presorted and TNF-α – populations. ( B ) Log fold-change of sgRNAs targeting the TSS of TNFA reveal correlation with TNF-α levels, thus validating the CRISPRa screening potential. ( C – F ) Log fold-change of sgRNAs targeting lncRNAs that positively ( lnc-MAP3K11-1 , C ) or negatively ( lnc-IL5-1 , D ; SENCR , E ; lncTMEM154-4 , F ) correlate with levels of TNF-α production.

Journal: JCI Insight

Article Title: Gene coexpression networks reveal a broad role for lncRNAs in inflammatory bowel disease

doi: 10.1172/jci.insight.168988

Figure Lengend Snippet: ( A ) THP-1 cells were stained for intracellular TNF-α and sorted into TNF-α + , TNF-α – , TNF-α hi , and TNF-α lo populations. Enrichment and depletion of sgRNAs in TNF-α subpopulations were compared with presorted and TNF-α – populations. ( B ) Log fold-change of sgRNAs targeting the TSS of TNFA reveal correlation with TNF-α levels, thus validating the CRISPRa screening potential. ( C – F ) Log fold-change of sgRNAs targeting lncRNAs that positively ( lnc-MAP3K11-1 , C ) or negatively ( lnc-IL5-1 , D ; SENCR , E ; lncTMEM154-4 , F ) correlate with levels of TNF-α production.

Article Snippet: An sgRNA CRISPRa library was designed and synthesized by the Broad Institute.

Techniques: Staining