cpsf3 protein expression Search Results


cpsf3 protein expression  (Human Protein Atlas)
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Human Protein Atlas cpsf3 protein expression
Analysis of the <t>CPSF3</t> gene expression in BC. A The Venn diagram suggested that the upregulation of CPSF3 was an unfavorable prognostic factor and positively correlated with the CD276 expression in bladder cancer (BC). B The heat map visualized the relative expression of 26 APA regulators in BC/normal (row 1) and the correlations of 26 regulators with the CD276 expression (row 2) and prognosis (row 3). The red color indicates a high expression in BC, positively correlated with CD276 or unfavorable prognosis. * p < 0.05 and ** p < 0.01. CPSF3 was upregulated in BC tissues compared to normal tissues.TCGA-BLCA cohort ( C ), GSE13507 ( D ), and GSE38264 ( E ). F Relative expression of CPSF3 was detected by qRT -PCR in 16 pairs of BC and normal tissues. G Compared with SV-HUC-1 cell line (normal), CPSF3 was highly expressed in EJ, T24, TCCSUP, UMUC3, 5637, RT4 cell lines (BC). H Immunohistochemistry staining indicated that, compared with normal bladder tissue (left), CPSF3 was significantly elevated in BC tissue (right) in the human protein atlas (antibody HPA034657, × 10). * p < 0.05, ** p < 0.01
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Analysis of the CPSF3 gene expression in BC. A The Venn diagram suggested that the upregulation of CPSF3 was an unfavorable prognostic factor and positively correlated with the CD276 expression in bladder cancer (BC). B The heat map visualized the relative expression of 26 APA regulators in BC/normal (row 1) and the correlations of 26 regulators with the CD276 expression (row 2) and prognosis (row 3). The red color indicates a high expression in BC, positively correlated with CD276 or unfavorable prognosis. * p < 0.05 and ** p < 0.01. CPSF3 was upregulated in BC tissues compared to normal tissues.TCGA-BLCA cohort ( C ), GSE13507 ( D ), and GSE38264 ( E ). F Relative expression of CPSF3 was detected by qRT -PCR in 16 pairs of BC and normal tissues. G Compared with SV-HUC-1 cell line (normal), CPSF3 was highly expressed in EJ, T24, TCCSUP, UMUC3, 5637, RT4 cell lines (BC). H Immunohistochemistry staining indicated that, compared with normal bladder tissue (left), CPSF3 was significantly elevated in BC tissue (right) in the human protein atlas (antibody HPA034657, × 10). * p < 0.05, ** p < 0.01

Journal: BMC Cancer

Article Title: Comprehensive analysis of alternative polyadenylation regulators concerning CD276 and immune infiltration in bladder cancer

doi: 10.1186/s12885-022-10103-7

Figure Lengend Snippet: Analysis of the CPSF3 gene expression in BC. A The Venn diagram suggested that the upregulation of CPSF3 was an unfavorable prognostic factor and positively correlated with the CD276 expression in bladder cancer (BC). B The heat map visualized the relative expression of 26 APA regulators in BC/normal (row 1) and the correlations of 26 regulators with the CD276 expression (row 2) and prognosis (row 3). The red color indicates a high expression in BC, positively correlated with CD276 or unfavorable prognosis. * p < 0.05 and ** p < 0.01. CPSF3 was upregulated in BC tissues compared to normal tissues.TCGA-BLCA cohort ( C ), GSE13507 ( D ), and GSE38264 ( E ). F Relative expression of CPSF3 was detected by qRT -PCR in 16 pairs of BC and normal tissues. G Compared with SV-HUC-1 cell line (normal), CPSF3 was highly expressed in EJ, T24, TCCSUP, UMUC3, 5637, RT4 cell lines (BC). H Immunohistochemistry staining indicated that, compared with normal bladder tissue (left), CPSF3 was significantly elevated in BC tissue (right) in the human protein atlas (antibody HPA034657, × 10). * p < 0.05, ** p < 0.01

Article Snippet: The protein expression level of CPSF3 in BC compared to normal tissue was obtained from the Human Protein Atlas database ( https://www.proteinatlas.org/ ).

Techniques: Gene Expression, Expressing, Quantitative RT-PCR, Immunohistochemistry, Staining

Upregulated CPSF3 expression is associated with poor outcomes of bladder cancer (BC). A , B , C The Kaplan–Meier analysis of BC patients with high and low CPSF3 expression level in the TCGA cohort for ( A ) overall surviva, ( B ) disease-specific surviva, ( C ) progress-free interval. D , E The stacked bar chart and violin plot visualized the proportion of live/death and survival time in high/low CPSF3 groups in BC patients. F Time-dependent receiver operating characteristics analysis of CPSF3. G , H Forest plots based upon the outcomes of univariate ( G ) and multivariate Cox regression ( H ) of CPSF3 expression and other clinicopathological factors. * p < 0.05

Journal: BMC Cancer

Article Title: Comprehensive analysis of alternative polyadenylation regulators concerning CD276 and immune infiltration in bladder cancer

doi: 10.1186/s12885-022-10103-7

Figure Lengend Snippet: Upregulated CPSF3 expression is associated with poor outcomes of bladder cancer (BC). A , B , C The Kaplan–Meier analysis of BC patients with high and low CPSF3 expression level in the TCGA cohort for ( A ) overall surviva, ( B ) disease-specific surviva, ( C ) progress-free interval. D , E The stacked bar chart and violin plot visualized the proportion of live/death and survival time in high/low CPSF3 groups in BC patients. F Time-dependent receiver operating characteristics analysis of CPSF3. G , H Forest plots based upon the outcomes of univariate ( G ) and multivariate Cox regression ( H ) of CPSF3 expression and other clinicopathological factors. * p < 0.05

Article Snippet: The protein expression level of CPSF3 in BC compared to normal tissue was obtained from the Human Protein Atlas database ( https://www.proteinatlas.org/ ).

Techniques: Expressing

Correlation analysis of CPSF3 expression with CD276 and infiltrating immune cells in bladder cancer (BC). A , B The enriched Gene Ontology ( A ) and Kyoto Encyclopedia of Genes and Genomes signaling pathways ( B ) analysis of highly expressed CPSF3 in BC. C Pearson correlation analysis of CPSF3 expression and CD276 expression in BC. D The infiltrating levels of immune cells in high and low CPSF3 expression groups in BC patients. ( E ) The heat map visualized the percentage abundance of tumor-infiltrating immune cells in each sample. * p < 0.05, ** p < 0.01, and *** p < 0.001

Journal: BMC Cancer

Article Title: Comprehensive analysis of alternative polyadenylation regulators concerning CD276 and immune infiltration in bladder cancer

doi: 10.1186/s12885-022-10103-7

Figure Lengend Snippet: Correlation analysis of CPSF3 expression with CD276 and infiltrating immune cells in bladder cancer (BC). A , B The enriched Gene Ontology ( A ) and Kyoto Encyclopedia of Genes and Genomes signaling pathways ( B ) analysis of highly expressed CPSF3 in BC. C Pearson correlation analysis of CPSF3 expression and CD276 expression in BC. D The infiltrating levels of immune cells in high and low CPSF3 expression groups in BC patients. ( E ) The heat map visualized the percentage abundance of tumor-infiltrating immune cells in each sample. * p < 0.05, ** p < 0.01, and *** p < 0.001

Article Snippet: The protein expression level of CPSF3 in BC compared to normal tissue was obtained from the Human Protein Atlas database ( https://www.proteinatlas.org/ ).

Techniques: Expressing, Protein-Protein interactions