col3a2 Search Results


gene exp col3a1 mm00802300 m1  (Thermo Fisher)
91
Thermo Fisher gene exp col3a1 mm00802300 m1
A , Experimental design of the preventative study using AAV-PERM1 in mice. Blue triangles indicate time points at which echocardiography was performed. B-C , Western blot analysis of cardiac tissue showing that TAC-induced downregulation of PERM1 was normalized by AAV-PERM1. D-E , Left ventricular ejection fraction (LVEF) in Sham and TAC mice at 8 weeks post-TAC, along with representative M-mode echocardiographic images for each group. The decline in LVEF observed in TAC mice was fully prevented by AAV-PERM1. F , Heart weight-to-body weight (HW/BW) ratio was increased by TAC, while no significant difference was observed between AAV-GFP Sham and AAV-PERM1 TAC groups, indicating that AAV-PERM1 prevented pathological cardiac hypertrophy. G-H , Masson’s trichrome staining of cardiac tissue revealed increased fibrosis in TAC hearts, which was suppressed by AAV-PERM1. I-J , qPCR analysis of cardiac tissue showed that expression of Nppb (BNP), a marker of cardiac stress, was increased by TAC but was suppressed by AAV-PERM1 ( I ), whereas expression of <t>Col3a1</t> , a gene involved in collagen formation, was increased in a subset of AAV-GFP mice subjected to TAC, was not significantly affected overall ( J ). *: p<0.05, **:p<0.01,***:p<0.001, ****p<0.0001, ns: not significant, by two-way ANOVA.
Gene Exp Col3a1 Mm00802300 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 91 stars, based on 1 article reviews
gene exp col3a1 mm00802300 m1 - by Bioz Stars, 2026-03
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col3a2  (ABclonal Biotechnology)
90
ABclonal Biotechnology col3a2
A , Experimental design of the preventative study using AAV-PERM1 in mice. Blue triangles indicate time points at which echocardiography was performed. B-C , Western blot analysis of cardiac tissue showing that TAC-induced downregulation of PERM1 was normalized by AAV-PERM1. D-E , Left ventricular ejection fraction (LVEF) in Sham and TAC mice at 8 weeks post-TAC, along with representative M-mode echocardiographic images for each group. The decline in LVEF observed in TAC mice was fully prevented by AAV-PERM1. F , Heart weight-to-body weight (HW/BW) ratio was increased by TAC, while no significant difference was observed between AAV-GFP Sham and AAV-PERM1 TAC groups, indicating that AAV-PERM1 prevented pathological cardiac hypertrophy. G-H , Masson’s trichrome staining of cardiac tissue revealed increased fibrosis in TAC hearts, which was suppressed by AAV-PERM1. I-J , qPCR analysis of cardiac tissue showed that expression of Nppb (BNP), a marker of cardiac stress, was increased by TAC but was suppressed by AAV-PERM1 ( I ), whereas expression of <t>Col3a1</t> , a gene involved in collagen formation, was increased in a subset of AAV-GFP mice subjected to TAC, was not significantly affected overall ( J ). *: p<0.05, **:p<0.01,***:p<0.001, ****p<0.0001, ns: not significant, by two-way ANOVA.
Col3a2, supplied by ABclonal Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/col3a2/product/ABclonal Biotechnology
Average 90 stars, based on 1 article reviews
col3a2 - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier

Image Search Results


A , Experimental design of the preventative study using AAV-PERM1 in mice. Blue triangles indicate time points at which echocardiography was performed. B-C , Western blot analysis of cardiac tissue showing that TAC-induced downregulation of PERM1 was normalized by AAV-PERM1. D-E , Left ventricular ejection fraction (LVEF) in Sham and TAC mice at 8 weeks post-TAC, along with representative M-mode echocardiographic images for each group. The decline in LVEF observed in TAC mice was fully prevented by AAV-PERM1. F , Heart weight-to-body weight (HW/BW) ratio was increased by TAC, while no significant difference was observed between AAV-GFP Sham and AAV-PERM1 TAC groups, indicating that AAV-PERM1 prevented pathological cardiac hypertrophy. G-H , Masson’s trichrome staining of cardiac tissue revealed increased fibrosis in TAC hearts, which was suppressed by AAV-PERM1. I-J , qPCR analysis of cardiac tissue showed that expression of Nppb (BNP), a marker of cardiac stress, was increased by TAC but was suppressed by AAV-PERM1 ( I ), whereas expression of Col3a1 , a gene involved in collagen formation, was increased in a subset of AAV-GFP mice subjected to TAC, was not significantly affected overall ( J ). *: p<0.05, **:p<0.01,***:p<0.001, ****p<0.0001, ns: not significant, by two-way ANOVA.

Journal: bioRxiv

Article Title: PERM1 Gene Delivery via AAV Prevents Heart Failure in a Mouse Model of Pressure Overload

doi: 10.1101/2025.09.29.679055

Figure Lengend Snippet: A , Experimental design of the preventative study using AAV-PERM1 in mice. Blue triangles indicate time points at which echocardiography was performed. B-C , Western blot analysis of cardiac tissue showing that TAC-induced downregulation of PERM1 was normalized by AAV-PERM1. D-E , Left ventricular ejection fraction (LVEF) in Sham and TAC mice at 8 weeks post-TAC, along with representative M-mode echocardiographic images for each group. The decline in LVEF observed in TAC mice was fully prevented by AAV-PERM1. F , Heart weight-to-body weight (HW/BW) ratio was increased by TAC, while no significant difference was observed between AAV-GFP Sham and AAV-PERM1 TAC groups, indicating that AAV-PERM1 prevented pathological cardiac hypertrophy. G-H , Masson’s trichrome staining of cardiac tissue revealed increased fibrosis in TAC hearts, which was suppressed by AAV-PERM1. I-J , qPCR analysis of cardiac tissue showed that expression of Nppb (BNP), a marker of cardiac stress, was increased by TAC but was suppressed by AAV-PERM1 ( I ), whereas expression of Col3a1 , a gene involved in collagen formation, was increased in a subset of AAV-GFP mice subjected to TAC, was not significantly affected overall ( J ). *: p<0.05, **:p<0.01,***:p<0.001, ****p<0.0001, ns: not significant, by two-way ANOVA.

Article Snippet: Taqman primers were purchased from ThermoFisher as follows: Nppb: Mm01255770_g1, Col3a2: Mm00802300_m1.

Techniques: Western Blot, Staining, Expressing, Marker