Journal: BioMed Research International

Article Title: Development of Alginate Microspheres Containing Chuanxiong for Oral Administration to Adult Zebrafish

doi: 10.1155/2016/4013071

Figure Lengend Snippet: The effect of drying on the size and weight of chuanxiong-loaded alginate microparticles. (a) The size of microparticles free of (0x) or encapsulated with chuanxiong. The time before drying was denoted by “0.” (b) The weight of microparticles free of or encapsulated with chuanxiong. Values represent the mean ± SD of 10 microparticles per group. ∗∗∗ P < 0.001 (between after time and before time in the same group).

Article Snippet: Chuanxiong (Kaiser Pharmaceutical Co., Ltd., Taiwan) was dissolved in distilled water for encapsulation by alginate microparticles and stored at −20°C until use.

Techniques:

Journal: BioMed Research International

Article Title: Development of Alginate Microspheres Containing Chuanxiong for Oral Administration to Adult Zebrafish

doi: 10.1155/2016/4013071

Figure Lengend Snippet: The swelling behavior of chuanxiong-loaded alginate microparticles. (a) The size of alginate microparticles free of or encapsulated with chuanxiong in water and simulated intestinal fluid. (b) The swelling rate of microparticles were compared with the same microparticle size between 24 hours and 0 mins in simulated intestinal fluid. Values represent the mean ± SD. ∗ P < 0.05; ∗∗ P < 0.01 (versus 0x group).

Article Snippet: Chuanxiong (Kaiser Pharmaceutical Co., Ltd., Taiwan) was dissolved in distilled water for encapsulation by alginate microparticles and stored at −20°C until use.

Techniques:

Journal: BioMed Research International

Article Title: Development of Alginate Microspheres Containing Chuanxiong for Oral Administration to Adult Zebrafish

doi: 10.1155/2016/4013071

Figure Lengend Snippet: The effect of chuanxiong on the structure of alginate microparticles. (a) The SEM analysis with amplification at 50x, 5000x, and 10000x. (b) The shape change rate of microparticles free of or encapsulated with chuanxiong. Values represent the mean ± SD. ∗∗ P < 0.01 (versus 0x group).

Article Snippet: Chuanxiong (Kaiser Pharmaceutical Co., Ltd., Taiwan) was dissolved in distilled water for encapsulation by alginate microparticles and stored at −20°C until use.

Techniques: Amplification

Journal: BioMed Research International

Article Title: Development of Alginate Microspheres Containing Chuanxiong for Oral Administration to Adult Zebrafish

doi: 10.1155/2016/4013071

Figure Lengend Snippet: The release efficiency of chuanxiong-loaded alginate microparticles. Values represent the mean ± SD. ∗ P < 0.05; ∗∗ P < 0.01; and ∗∗∗ P < 0.001 (between after time and before time in the same group).

Article Snippet: Chuanxiong (Kaiser Pharmaceutical Co., Ltd., Taiwan) was dissolved in distilled water for encapsulation by alginate microparticles and stored at −20°C until use.

Techniques:

Journal: BioMed Research International

Article Title: Development of Alginate Microspheres Containing Chuanxiong for Oral Administration to Adult Zebrafish

doi: 10.1155/2016/4013071

Figure Lengend Snippet: Characteristics of chuanxiong-loaded alginate microparticles. Values represent the mean ± SD. ∗ P < 0.05; ∗∗ P < 0.01; and ∗∗∗ P < 0.001 (versus 0.5x group).

Article Snippet: Chuanxiong (Kaiser Pharmaceutical Co., Ltd., Taiwan) was dissolved in distilled water for encapsulation by alginate microparticles and stored at −20°C until use.

Techniques: Encapsulation

Journal: BioMed Research International

Article Title: Development of Alginate Microspheres Containing Chuanxiong for Oral Administration to Adult Zebrafish

doi: 10.1155/2016/4013071

Figure Lengend Snippet: The analysis of chuanxiong-loaded alginate microparticles in zebrafish intestine. The microparticles were excreted after 16 h as shown in the fluorescent field.

Article Snippet: Chuanxiong (Kaiser Pharmaceutical Co., Ltd., Taiwan) was dissolved in distilled water for encapsulation by alginate microparticles and stored at −20°C until use.

Techniques:

Journal: Chinese Medicine

Article Title: Integrated metabolomics and the microbiome reveal the compatibility mechanism of the Suxiao Jiuxin pill in the treatment of stable coronary artery disease

doi: 10.1186/s13020-025-01198-8

Figure Lengend Snippet: LC‒MS analysis of blood components in Chuanxiong Rhizoma. A Flowchart of the animal experiments involving Chuanxiong Rhizoma and borneol treatment. B The effective components of Chuanxiong Rhizoma were detected in mouse serum. Heatmap of the absorption of the effective components of Chuanxiong Rhizoma into the blood without ( C ) and with ( D ) ABX treatment. Statistical significance was tested by Student’s t test; *, p < 0.05; **, p < 0.01; ***, p < 0.001

Article Snippet: Chuanxiong Rhizoma (batch number: B26040 ) and borneol (batch number: S47379 ) were acquired from Shanghai Yuanye Bio-Technology Co., Ltd. (Shanghai, China).

Techniques:

Journal: Chinese Medicine

Article Title: Integrated metabolomics and the microbiome reveal the compatibility mechanism of the Suxiao Jiuxin pill in the treatment of stable coronary artery disease

doi: 10.1186/s13020-025-01198-8

Figure Lengend Snippet: Volcano plots of DMs between the CR and Con groups ( A ), the CR_Bor_L and Con groups ( B ) and the CR_Bor_H and Con groups ( C ). D PLS-DA score plots of the Con, CR, CR_Bor_L, and CR_Bor_H groups. E Categories and percentages of all DMs. F The categories and number of DMs were obtained from the CR, CR_Bor_L, and CR_Bor_H groups. G Heatmap of Borneol dose-dependently related DMs in the CR, CR_Bor_L, and CR_Bor_H groups. H Correlation analysis of the serum effective constituents of Chuanxiong Rhizoma and borneol dose-dependently related to DMs

Article Snippet: Chuanxiong Rhizoma (batch number: B26040 ) and borneol (batch number: S47379 ) were acquired from Shanghai Yuanye Bio-Technology Co., Ltd. (Shanghai, China).

Techniques:

Journal: Chinese Medicine

Article Title: Integrated metabolomics and the microbiome reveal the compatibility mechanism of the Suxiao Jiuxin pill in the treatment of stable coronary artery disease

doi: 10.1186/s13020-025-01198-8

Figure Lengend Snippet: Correlation analysis between DMs in a dose-dependent manner and borneol and the gut microbiota ( A ) and Chuanxiong Rhizoma blood components ( B )

Article Snippet: Chuanxiong Rhizoma (batch number: B26040 ) and borneol (batch number: S47379 ) were acquired from Shanghai Yuanye Bio-Technology Co., Ltd. (Shanghai, China).

Techniques:

Journal: Chinese Medicine

Article Title: Integrated metabolomics and the microbiome reveal the compatibility mechanism of the Suxiao Jiuxin pill in the treatment of stable coronary artery disease

doi: 10.1186/s13020-025-01198-8

Figure Lengend Snippet: Analysis of metabolites and blood components after combined administration of A. muciniphila bacteria and Chuanxiong Rhizoma . A Flowchart of the animal experiments. B PCA score plot of the QC, ABX_CR, and ABX_AKK_CR groups. C Volcano plot of DMs between the ABX_AKK_CR and ABX_CR groups. D Heatmap of DMs in the ABX_CR and ABX_AKK_CR groups. E Changes in metabolic pathways induced by AKK (ABX_AKK_CR vs. ABX_CR) in the serum. F Heatmap of the absorption of the effective components of Chuanxiong Rhizoma into the blood without and with A. muciniphila treatment

Article Snippet: Chuanxiong Rhizoma (batch number: B26040 ) and borneol (batch number: S47379 ) were acquired from Shanghai Yuanye Bio-Technology Co., Ltd. (Shanghai, China).

Techniques: Bacteria