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Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3
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Becton Dickinson
cd8 (sk1, 5ul) ![]() Cd8 (Sk1, 5ul), supplied by Becton Dickinson, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/cd8+apc+cy7/cd8+sk1++apc+199+cy7+antibody/pmc04881966-88-25-35 Average 90 stars, based on 1 article reviews
cd8 (sk1, 5ul) - by Bioz Stars,
2026-09
90/100 stars
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QuantoBio
anti-cd8-apc-cy7 ![]() Anti Cd8 Apc Cy7, supplied by QuantoBio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/cd8+apc+cy7/anti+cd8+apc+cy7/pmc08924605-59-10-11 Average 90 stars, based on 1 article reviews
anti-cd8-apc-cy7 - by Bioz Stars,
2026-09
90/100 stars
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Becton Dickinson
anti-human cd8 antibody pharmin, apc-cy™7 ![]() Anti Human Cd8 Antibody Pharmin, Apc Cy™7, supplied by Becton Dickinson, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/cd8+apc+cy7/anti+human+cd8+antibody+pharmin++apc+cy+7/bio_rxiv__2022__03__01__482445-143-6-9 Average 90 stars, based on 1 article reviews
anti-human cd8 antibody pharmin, apc-cy™7 - by Bioz Stars,
2026-09
90/100 stars
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APC/Cy7 anti-human CD8 [SK1]; Isotype: Mouse IgG1, κ; Reactivity: Human, Cross-Reactivity: African Green, Chimpanzee, Cynomolgus, Pigtailed Macaque, Rhesus, Sooty Mangabey ; Apps: FC; Size: 25 tests
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The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T
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CD8 clone SK1 is derived from hybridization of mouse NS 1 myeloma cells with spleen cells from BALB c mice immunized with human peripheral blood T lymphocytes CD8 clone SK1 is derived from hybridization of
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Image Search Results
Journal: PLoS ONE
Article Title: Analysis of the In Vivo Turnover of CD4+ T-Cell Subsets in Chronically SIV-Infected Sooty Mangabeys
doi: 10.1371/journal.pone.0156352
Figure Lengend Snippet: The mean (±SEM) percent Ki67+ (A+B) and percent BrdU+ (C+D) of peripheral blood CD4+ (A+C) and CD8+ (B+D) T-cells were assessed longitudinally by flow cytometry in both uninfected (black squares) and infected (red circles) animals. p = NS between infected and uninfected controls at all timepoints for all populations (Mann-Whitney U). Shaded area represents BrdU administration period. Data points are shown only for animals above which 100 events were collected for the parent population.
Article Snippet: Mouse-derived monoclonal antibodies directed against the following antigens were used at titration-assessed volumes as follows: BrdU (clone 3D4, 20uL), CCR5 (3A9, 10uL), CD3 (SP34-2, 5uL),
Techniques: Flow Cytometry, Infection, MANN-WHITNEY
Journal: PLoS ONE
Article Title: Analysis of the In Vivo Turnover of CD4+ T-Cell Subsets in Chronically SIV-Infected Sooty Mangabeys
doi: 10.1371/journal.pone.0156352
Figure Lengend Snippet: A-B. (±SEM) percent BrdU expression was assessed longitudinally by flow cytometry among CD4+ (A) and CD8+ (B) T N , T CM , T TM , T EM , and CCR5+ TM in uninfected (left) and SIV-infected (right) animals. C. Mean (±SEM) longitudinal Ki67 expression of CD4+ T N , T CM , T TM , T EM , and CCR5+ TM in uninfected (left) and SIV-infected (right) animals. p = NS between infected and uninfected controls at all timepoints for all populations (Mann-Whitney U). Shaded area represents BrdU administration period. Data points are shown only for animals above which 100 events were collected for the parent population.
Article Snippet: Mouse-derived monoclonal antibodies directed against the following antigens were used at titration-assessed volumes as follows: BrdU (clone 3D4, 20uL), CCR5 (3A9, 10uL), CD3 (SP34-2, 5uL),
Techniques: Expressing, Flow Cytometry, Infection, MANN-WHITNEY
Journal: bioRxiv
Article Title: Balancing activation and costimulation of CAR tunes signaling dynamics and enhances therapeutic potency
doi: 10.1101/2022.03.01.482445
Figure Lengend Snippet: CD19-1XX CAR-T cells show better anti-tumor activity in a pancreatic tumor model in vivo. (a) Timeline of of CD19 CAR-T treatment in mouse model. (b) Panc-1 CD19+ -bearing mice were treated with 1 × 10 6 CD19 CAR-T cells as indicated and tumor burden (tumor volume) of mice was measured at indicated days (n=4 mice each group). For mouse experiments, Control, PBS. (c) Tumor tissue from mice treated with indicated CAR-T cells. (d) Tumor tissue from mice treated with indicated CAR-T cells was sliced and stained with antibodies against human CD4 and CD8 (n=4). The percentage of CD4 + (e) and CD8 + (f) T cells in tumor tissue from different groups of mice (n=4). All data are mean ± SEM.
Article Snippet: Anti-Human CD4 antibody (BD, Horizon, BUV395),
Techniques: Activity Assay, In Vivo, Staining
Journal: bioRxiv
Article Title: Balancing activation and costimulation of CAR tunes signaling dynamics and enhances therapeutic potency
doi: 10.1101/2022.03.01.482445
Figure Lengend Snippet: 1XX modification of AXL CAR enhance its anti-tumor activity in a melanoma tumor model. (a) Timeline of of AXL CAR-T treatment in mouse model. (b) A375-bearing mice were treated with 2.5 × 10 6 AXL CAR-T cells and tumor burden (tumor volume) of mice were measured at indicated days (n=4, 5, 5 mice in respective groups). Control, PBS. (c) Tumor tissue of mice treated with indicated CAR-T cells (n=4, 5, 5). (d) The weight of tumors from different groups of mice (n=4, 5, 5). Number of CAR-T(e), CD4 + CAR-T cells (f) and CD8 + CAR-T cells (g) in spleen of mice 20 days post CAR-T infusion (n=5, 3). (h-k) Phenotype of CAR-T cells in the spleen of mice 20 days after CAR-T infusion as demonstrated by the percentage of T CM (CD45RA - CD62L + ) and T EFF (CD45RA + CD62L - ) cells (n=5, 3). All data are mean ± SEM.
Article Snippet: Anti-Human CD4 antibody (BD, Horizon, BUV395),
Techniques: Modification, Activity Assay