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Miltenyi Biotec
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Miltenyi Biotec
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Journal: International Journal of Molecular Sciences
Article Title: Neuroendocrine Differentiation of Lung Cancer Cells Impairs the Activation of Antitumor Cytotoxic Responses in Mice
doi: 10.3390/ijms24020990
Figure Lengend Snippet: Changes in PBMC profiles after immunization. Flow cytometric analysis of PBMC samples obtained from the different groups of mice, targeting CD68 (a monocyte/macrophage cellular marker), CD4 (a co-receptor for the T cell receptor and specific marker of T helper cells), CD8a (a co-receptor for the T cell receptor and specific marker of cytotoxic T cells), and CD335 (a cytotoxicity-activating receptor that mediates tumor cell lysis and distinguishes NK cells from other populations). The bar graphs show the percentage of CD68 + ( A ), CD4 + ( B ), CD8 + ( C ), double positive CD4 + /CD8 + ( D ), and CD335 + ( E ) cells in PBMCs from the different groups of mice. Results are presented as the mean ± SEM (n = 4, ** p < 0.01, * p < 0.05, # p < 0.1).
Article Snippet:
Techniques: Marker, Lysis