c-src Search Results


src targeting sirna sc 5266  (Santa Cruz Biotechnology)
97
Santa Cruz Biotechnology src targeting sirna sc 5266
Src Targeting Sirna Sc 5266, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/c-src/pmc13046926-253-2-8?v=Santa+Cruz+Biotechnology
Average 97 stars, based on 1 article reviews
src targeting sirna sc 5266 - by Bioz Stars, 2026-08
97/100 stars
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kinase dead k298m c src  (Addgene inc)
93
Addgene inc kinase dead k298m c src
Concentration-response relationships of DAMGO as a recruiter of β-arrestin2 to μ receptors in PathHunter CHO cells transiently overexpressing ( A ) full-length (residues 1-536; WT) versus C-terminally truncated (residues 1-249) human c-Src and ( B ) functional (residues 250-536) versus catalytically non-functional (residues <t>250-536(K298M))</t> N-terminally truncated human c-Src. The insert in (A) demonstrates overexpression of C-terminally truncated c-Src using an antibody against HA (1:1000). Overexpression of other c-Src mutants is depicted in Supplementary Figure 5A. WT responses in (B) are depicted as a dashed line. Data are expressed as a percentage of maximum luminescence produced by DAMGO in cells overexpressing WT c-Src (% WT). Data from individual replicates were plotted and fitted with logistics functions to derive efficacy (E MAX ) and potency (EC 50 ) parameters, presented in . Data in A and B are the mean ± SEM of 9 replicates.
Kinase Dead K298m C Src, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/c-src/bio_rxiv__2025__07__01__662507-254-31-38?v=Addgene+inc
Average 93 stars, based on 1 article reviews
kinase dead k298m c src - by Bioz Stars, 2026-08
93/100 stars
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c src sirna h si src  (Santa Cruz Biotechnology)
93
Santa Cruz Biotechnology c src sirna h si src
Concentration-response relationships of DAMGO as a recruiter of β-arrestin2 to μ receptors in PathHunter CHO cells transiently overexpressing ( A ) full-length (residues 1-536; WT) versus C-terminally truncated (residues 1-249) human c-Src and ( B ) functional (residues 250-536) versus catalytically non-functional (residues <t>250-536(K298M))</t> N-terminally truncated human c-Src. The insert in (A) demonstrates overexpression of C-terminally truncated c-Src using an antibody against HA (1:1000). Overexpression of other c-Src mutants is depicted in Supplementary Figure 5A. WT responses in (B) are depicted as a dashed line. Data are expressed as a percentage of maximum luminescence produced by DAMGO in cells overexpressing WT c-Src (% WT). Data from individual replicates were plotted and fitted with logistics functions to derive efficacy (E MAX ) and potency (EC 50 ) parameters, presented in . Data in A and B are the mean ± SEM of 9 replicates.
C Src Sirna H Si Src, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/c-src/pmc08944659-57-8-29?v=Santa+Cruz+Biotechnology
Average 93 stars, based on 1 article reviews
c src sirna h si src - by Bioz Stars, 2026-08
93/100 stars
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recombinant human src proto oncogene c src protein  (Elabscience Biotechnology)
92
Elabscience Biotechnology recombinant human src proto oncogene c src protein
Concentration-response relationships of DAMGO as a recruiter of β-arrestin2 to μ receptors in PathHunter CHO cells transiently overexpressing ( A ) full-length (residues 1-536; WT) versus C-terminally truncated (residues 1-249) human c-Src and ( B ) functional (residues 250-536) versus catalytically non-functional (residues <t>250-536(K298M))</t> N-terminally truncated human c-Src. The insert in (A) demonstrates overexpression of C-terminally truncated c-Src using an antibody against HA (1:1000). Overexpression of other c-Src mutants is depicted in Supplementary Figure 5A. WT responses in (B) are depicted as a dashed line. Data are expressed as a percentage of maximum luminescence produced by DAMGO in cells overexpressing WT c-Src (% WT). Data from individual replicates were plotted and fitted with logistics functions to derive efficacy (E MAX ) and potency (EC 50 ) parameters, presented in . Data in A and B are the mean ± SEM of 9 replicates.
Recombinant Human Src Proto Oncogene C Src Protein, supplied by Elabscience Biotechnology, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/c-src/pmc11204876-279-25-24?v=Elabscience+Biotechnology
Average 92 stars, based on 1 article reviews
recombinant human src proto oncogene c src protein - by Bioz Stars, 2026-08
92/100 stars
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dna  (OriGene)
90
OriGene dna
Concentration-response relationships of DAMGO as a recruiter of β-arrestin2 to μ receptors in PathHunter CHO cells transiently overexpressing ( A ) full-length (residues 1-536; WT) versus C-terminally truncated (residues 1-249) human c-Src and ( B ) functional (residues 250-536) versus catalytically non-functional (residues <t>250-536(K298M))</t> N-terminally truncated human c-Src. The insert in (A) demonstrates overexpression of C-terminally truncated c-Src using an antibody against HA (1:1000). Overexpression of other c-Src mutants is depicted in Supplementary Figure 5A. WT responses in (B) are depicted as a dashed line. Data are expressed as a percentage of maximum luminescence produced by DAMGO in cells overexpressing WT c-Src (% WT). Data from individual replicates were plotted and fitted with logistics functions to derive efficacy (E MAX ) and potency (EC 50 ) parameters, presented in . Data in A and B are the mean ± SEM of 9 replicates.
Dna, supplied by OriGene, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/c-src/pmc06207713__41467_2018_6790_MOESM1_ESM-88-28-33?v=OriGene
Average 90 stars, based on 1 article reviews
dna - by Bioz Stars, 2026-08
90/100 stars
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pcdna3 src plasmids  (Addgene inc)
93
Addgene inc pcdna3 src plasmids
Concentration-response relationships of DAMGO as a recruiter of β-arrestin2 to μ receptors in PathHunter CHO cells transiently overexpressing ( A ) full-length (residues 1-536; WT) versus C-terminally truncated (residues 1-249) human c-Src and ( B ) functional (residues 250-536) versus catalytically non-functional (residues <t>250-536(K298M))</t> N-terminally truncated human c-Src. The insert in (A) demonstrates overexpression of C-terminally truncated c-Src using an antibody against HA (1:1000). Overexpression of other c-Src mutants is depicted in Supplementary Figure 5A. WT responses in (B) are depicted as a dashed line. Data are expressed as a percentage of maximum luminescence produced by DAMGO in cells overexpressing WT c-Src (% WT). Data from individual replicates were plotted and fitted with logistics functions to derive efficacy (E MAX ) and potency (EC 50 ) parameters, presented in . Data in A and B are the mean ± SEM of 9 replicates.
Pcdna3 Src Plasmids, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/c-src/pmc05422711__onc2016415x1-82-4-9?v=Addgene+inc
Average 93 stars, based on 1 article reviews
pcdna3 src plasmids - by Bioz Stars, 2026-08
93/100 stars
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src mcherry  (Addgene inc)
91
Addgene inc src mcherry
Concentration-response relationships of DAMGO as a recruiter of β-arrestin2 to μ receptors in PathHunter CHO cells transiently overexpressing ( A ) full-length (residues 1-536; WT) versus C-terminally truncated (residues 1-249) human c-Src and ( B ) functional (residues 250-536) versus catalytically non-functional (residues <t>250-536(K298M))</t> N-terminally truncated human c-Src. The insert in (A) demonstrates overexpression of C-terminally truncated c-Src using an antibody against HA (1:1000). Overexpression of other c-Src mutants is depicted in Supplementary Figure 5A. WT responses in (B) are depicted as a dashed line. Data are expressed as a percentage of maximum luminescence produced by DAMGO in cells overexpressing WT c-Src (% WT). Data from individual replicates were plotted and fitted with logistics functions to derive efficacy (E MAX ) and potency (EC 50 ) parameters, presented in . Data in A and B are the mean ± SEM of 9 replicates.
Src Mcherry, supplied by Addgene inc, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/c-src/pmc08850434-338-4-18?v=Addgene+inc
Average 91 stars, based on 1 article reviews
src mcherry - by Bioz Stars, 2026-08
91/100 stars
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pcmv6 src  (OriGene)
90
OriGene pcmv6 src
Concentration-response relationships of DAMGO as a recruiter of β-arrestin2 to μ receptors in PathHunter CHO cells transiently overexpressing ( A ) full-length (residues 1-536; WT) versus C-terminally truncated (residues 1-249) human c-Src and ( B ) functional (residues 250-536) versus catalytically non-functional (residues <t>250-536(K298M))</t> N-terminally truncated human c-Src. The insert in (A) demonstrates overexpression of C-terminally truncated c-Src using an antibody against HA (1:1000). Overexpression of other c-Src mutants is depicted in Supplementary Figure 5A. WT responses in (B) are depicted as a dashed line. Data are expressed as a percentage of maximum luminescence produced by DAMGO in cells overexpressing WT c-Src (% WT). Data from individual replicates were plotted and fitted with logistics functions to derive efficacy (E MAX ) and potency (EC 50 ) parameters, presented in . Data in A and B are the mean ± SEM of 9 replicates.
Pcmv6 Src, supplied by OriGene, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/c-src/pmc06207713-213-4-5?v=OriGene
Average 90 stars, based on 1 article reviews
pcmv6 src - by Bioz Stars, 2026-08
90/100 stars
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pcdna3 mts wt csrc flag  (Addgene inc)
93
Addgene inc pcdna3 mts wt csrc flag
Concentration-response relationships of DAMGO as a recruiter of β-arrestin2 to μ receptors in PathHunter CHO cells transiently overexpressing ( A ) full-length (residues 1-536; WT) versus C-terminally truncated (residues 1-249) human c-Src and ( B ) functional (residues 250-536) versus catalytically non-functional (residues <t>250-536(K298M))</t> N-terminally truncated human c-Src. The insert in (A) demonstrates overexpression of C-terminally truncated c-Src using an antibody against HA (1:1000). Overexpression of other c-Src mutants is depicted in Supplementary Figure 5A. WT responses in (B) are depicted as a dashed line. Data are expressed as a percentage of maximum luminescence produced by DAMGO in cells overexpressing WT c-Src (% WT). Data from individual replicates were plotted and fitted with logistics functions to derive efficacy (E MAX ) and potency (EC 50 ) parameters, presented in . Data in A and B are the mean ± SEM of 9 replicates.
Pcdna3 Mts Wt Csrc Flag, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/c-src/pmc11459124__pnas__2417731121__sapp-55-24-31?v=Addgene+inc
Average 93 stars, based on 1 article reviews
pcdna3 mts wt csrc flag - by Bioz Stars, 2026-08
93/100 stars
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p c src  (Santa Cruz Biotechnology)
93
Santa Cruz Biotechnology p c src
Concentration-response relationships of DAMGO as a recruiter of β-arrestin2 to μ receptors in PathHunter CHO cells transiently overexpressing ( A ) full-length (residues 1-536; WT) versus C-terminally truncated (residues 1-249) human c-Src and ( B ) functional (residues 250-536) versus catalytically non-functional (residues <t>250-536(K298M))</t> N-terminally truncated human c-Src. The insert in (A) demonstrates overexpression of C-terminally truncated c-Src using an antibody against HA (1:1000). Overexpression of other c-Src mutants is depicted in Supplementary Figure 5A. WT responses in (B) are depicted as a dashed line. Data are expressed as a percentage of maximum luminescence produced by DAMGO in cells overexpressing WT c-Src (% WT). Data from individual replicates were plotted and fitted with logistics functions to derive efficacy (E MAX ) and potency (EC 50 ) parameters, presented in . Data in A and B are the mean ± SEM of 9 replicates.
P C Src, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/c-src/pm28704617-34-21-71?v=Santa+Cruz+Biotechnology
Average 93 stars, based on 1 article reviews
p c src - by Bioz Stars, 2026-08
93/100 stars
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src  (Proteintech)
95
Proteintech src
Concentration-response relationships of DAMGO as a recruiter of β-arrestin2 to μ receptors in PathHunter CHO cells transiently overexpressing ( A ) full-length (residues 1-536; WT) versus C-terminally truncated (residues 1-249) human c-Src and ( B ) functional (residues 250-536) versus catalytically non-functional (residues <t>250-536(K298M))</t> N-terminally truncated human c-Src. The insert in (A) demonstrates overexpression of C-terminally truncated c-Src using an antibody against HA (1:1000). Overexpression of other c-Src mutants is depicted in Supplementary Figure 5A. WT responses in (B) are depicted as a dashed line. Data are expressed as a percentage of maximum luminescence produced by DAMGO in cells overexpressing WT c-Src (% WT). Data from individual replicates were plotted and fitted with logistics functions to derive efficacy (E MAX ) and potency (EC 50 ) parameters, presented in . Data in A and B are the mean ± SEM of 9 replicates.
Src, supplied by Proteintech, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/c-src/pm41923217-130-27-28?v=Proteintech
Average 95 stars, based on 1 article reviews
src - by Bioz Stars, 2026-08
95/100 stars
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human src enzyme  (Carna Inc)
95
Carna Inc human src enzyme
Concentration-response relationships of DAMGO as a recruiter of β-arrestin2 to μ receptors in PathHunter CHO cells transiently overexpressing ( A ) full-length (residues 1-536; WT) versus C-terminally truncated (residues 1-249) human c-Src and ( B ) functional (residues 250-536) versus catalytically non-functional (residues <t>250-536(K298M))</t> N-terminally truncated human c-Src. The insert in (A) demonstrates overexpression of C-terminally truncated c-Src using an antibody against HA (1:1000). Overexpression of other c-Src mutants is depicted in Supplementary Figure 5A. WT responses in (B) are depicted as a dashed line. Data are expressed as a percentage of maximum luminescence produced by DAMGO in cells overexpressing WT c-Src (% WT). Data from individual replicates were plotted and fitted with logistics functions to derive efficacy (E MAX ) and potency (EC 50 ) parameters, presented in . Data in A and B are the mean ± SEM of 9 replicates.
Human Src Enzyme, supplied by Carna Inc, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/c-src/us10479780-2133-23-28?v=Carna+Inc
Average 95 stars, based on 1 article reviews
human src enzyme - by Bioz Stars, 2026-08
95/100 stars
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Image Search Results


Concentration-response relationships of DAMGO as a recruiter of β-arrestin2 to μ receptors in PathHunter CHO cells transiently overexpressing ( A ) full-length (residues 1-536; WT) versus C-terminally truncated (residues 1-249) human c-Src and ( B ) functional (residues 250-536) versus catalytically non-functional (residues 250-536(K298M)) N-terminally truncated human c-Src. The insert in (A) demonstrates overexpression of C-terminally truncated c-Src using an antibody against HA (1:1000). Overexpression of other c-Src mutants is depicted in Supplementary Figure 5A. WT responses in (B) are depicted as a dashed line. Data are expressed as a percentage of maximum luminescence produced by DAMGO in cells overexpressing WT c-Src (% WT). Data from individual replicates were plotted and fitted with logistics functions to derive efficacy (E MAX ) and potency (EC 50 ) parameters, presented in . Data in A and B are the mean ± SEM of 9 replicates.

Journal: bioRxiv

Article Title: The c-Src inhibitor eCF506 diminishes opioid tolerance creating bias against β-arrestin2 recruitment

doi: 10.1101/2025.07.01.662507

Figure Lengend Snippet: Concentration-response relationships of DAMGO as a recruiter of β-arrestin2 to μ receptors in PathHunter CHO cells transiently overexpressing ( A ) full-length (residues 1-536; WT) versus C-terminally truncated (residues 1-249) human c-Src and ( B ) functional (residues 250-536) versus catalytically non-functional (residues 250-536(K298M)) N-terminally truncated human c-Src. The insert in (A) demonstrates overexpression of C-terminally truncated c-Src using an antibody against HA (1:1000). Overexpression of other c-Src mutants is depicted in Supplementary Figure 5A. WT responses in (B) are depicted as a dashed line. Data are expressed as a percentage of maximum luminescence produced by DAMGO in cells overexpressing WT c-Src (% WT). Data from individual replicates were plotted and fitted with logistics functions to derive efficacy (E MAX ) and potency (EC 50 ) parameters, presented in . Data in A and B are the mean ± SEM of 9 replicates.

Article Snippet: All constructs are based on human c-Src WT (1-536) c-Src (plasmid #42202; RRID: Addgene_42202), c-terminus truncated (1-249) c-Src (plasmid #42204; RRID: Addgene_42204), n-terminus truncated (250-536) c-Src (plasmid #42208; RRID: Addgene_42208), and kinase dead (K298M) c-Src (plasmid #42210; RRID: Addgene_42210), were donated by Dr Robert Lefkowitz.

Techniques: Concentration Assay, Functional Assay, Over Expression, Produced

Concentration-response relationships of DAMGO to recruit β-arrestin2 to human μ receptors in PathHunter CHO cells transiently overexpressing ( A ) full-length (residues 1-536; WT), ( B ) C-terminally truncated (residues 1-249) or ( C ) N-terminally truncated and catalytically inactive (residues 250-536(K298M)) human c-Src following 16-h exposure to PP2, PP3, eCF506 (300 nM) or an equal volume of DMSO. Data are expressed as a percentage of maximum luminescence (% Max RLU) produced by DAMGO in DMSO exposed cells present in duplicate on each plate i.e., cells overexpressing (A) WT, (B) Src 1-249 or (C) Src 250-536(K298M) are each expressed relative to the maximum β-arrestin2 recruitment of each construct caused by DAMGO. Data from individual replicates were plotted and fitted with logistics functions to derive efficacy (E MAX ) and potency (EC 50 ) parameters, presented in Supplementary Table 3. Data are the mean ± SEM of 5-6 replicates.

Journal: bioRxiv

Article Title: The c-Src inhibitor eCF506 diminishes opioid tolerance creating bias against β-arrestin2 recruitment

doi: 10.1101/2025.07.01.662507

Figure Lengend Snippet: Concentration-response relationships of DAMGO to recruit β-arrestin2 to human μ receptors in PathHunter CHO cells transiently overexpressing ( A ) full-length (residues 1-536; WT), ( B ) C-terminally truncated (residues 1-249) or ( C ) N-terminally truncated and catalytically inactive (residues 250-536(K298M)) human c-Src following 16-h exposure to PP2, PP3, eCF506 (300 nM) or an equal volume of DMSO. Data are expressed as a percentage of maximum luminescence (% Max RLU) produced by DAMGO in DMSO exposed cells present in duplicate on each plate i.e., cells overexpressing (A) WT, (B) Src 1-249 or (C) Src 250-536(K298M) are each expressed relative to the maximum β-arrestin2 recruitment of each construct caused by DAMGO. Data from individual replicates were plotted and fitted with logistics functions to derive efficacy (E MAX ) and potency (EC 50 ) parameters, presented in Supplementary Table 3. Data are the mean ± SEM of 5-6 replicates.

Article Snippet: All constructs are based on human c-Src WT (1-536) c-Src (plasmid #42202; RRID: Addgene_42202), c-terminus truncated (1-249) c-Src (plasmid #42204; RRID: Addgene_42204), n-terminus truncated (250-536) c-Src (plasmid #42208; RRID: Addgene_42208), and kinase dead (K298M) c-Src (plasmid #42210; RRID: Addgene_42210), were donated by Dr Robert Lefkowitz.

Techniques: Concentration Assay, Produced, Construct