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Image Search Results
Journal: BMC Systems Biology
Article Title: Evolution of computational models in BioModels Database and the Physiome Model Repository
doi: 10.1186/s12918-018-0553-2
Figure Lengend Snippet: Types of diff operations. The boxplots quantify the types of changes (left boxplots) and affected components in the XML documents (right boxplots) in BioModels Database (boxplots 1 and 3) and the Physiome Model Repository (boxplots 2 and 4)
Article Snippet: The
Techniques:
Journal: ACS Chemical Biology
Article Title: Antimicrobial Agent Trimethoprim Influences Chemical Interactions in Cystic Fibrosis Pathogens via the ham Gene Cluster
doi: 10.1021/acschembio.4c00562
Figure Lengend Snippet: Fungal siderophore triacetylfusarinin C detected upon cocultivation of A. fumigatus and B. cenocepacia . (a) Molecular network of TAFC analogues connected via FBMN or MS2LDA. (b) Mass2Motif 559 corresponding to the TAFC substructure. (c) Boxplots of the relative abundance of TAFC and TAFC-iron complex in extracts derived from A. fumigatus monocultures and A. fumigatus + B. cenocepacia cocultures in the presence and absence of trimethoprim. Asterisks indicate the significant differences between the compared groups, as determined by the Kruskal–Wallis test with Dunn’s post-test (adjusted p -value <0.05). (d) MALDI-MSI-derived images for TAFC in mono- and cocultures. The visualization of the spatial distribution of TAFC is shown as a heatmap in false color (cyan, m / z 875.401, [M + Na] + ). A white rectangle represents the measurement area used for data acquisition.
Article Snippet:
Techniques: Analogues, Derivative Assay
Journal: ACS Chemical Biology
Article Title: Antimicrobial Agent Trimethoprim Influences Chemical Interactions in Cystic Fibrosis Pathogens via the ham Gene Cluster
doi: 10.1021/acschembio.4c00562
Figure Lengend Snippet: Shift in chemical interactions between B. cenocepacia and A. fumigatus in the absence of the functional ham gene cluster. Boxplots of the relative abundance of (a) triacetylfusarinin C, (b) the ergosterol-related compound with m / z 496.415, (c) the unknown compound 1 with m / z 318.202, and (d) the unknown compound 2 with m / z 304.223 in the extracts derived from A. fumigatus monocultures and cocultures with either B. cenocepacia WT or Δ hamC strains in the presence and absence of sublethal trimethoprim.
Article Snippet:
Techniques: Functional Assay, Derivative Assay