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Commonly used NAAT platforms for STI agents with 1- to 2-h turnaround times

Journal: Journal of Clinical Microbiology

Article Title: Laboratory Diagnosis of Sexually Transmitted Infections in Cases of Suspected Child Sexual Abuse

doi: 10.1128/JCM.01433-19

Figure Lengend Snippet: Commonly used NAAT platforms for STI agents with 1- to 2-h turnaround times

Article Snippet: Simplexa , Focus Diagnostics , , , , , , , X.

Techniques:

FDA-cleared molecular assays for the detection of C. difficile and available pediatric data from package inserts

Journal: Journal of Clinical Microbiology

Article Title: Diagnosis of Clostridium difficile Infections in Children

doi: 10.1128/JCM.03014-15

Figure Lengend Snippet: FDA-cleared molecular assays for the detection of C. difficile and available pediatric data from package inserts

Article Snippet: Additional FDA-cleared assays have not been evaluated exclusively in pediatric patients (Focus Diagnostics Simplexa, Great Basin Portrait, Verigene, IMDx Abbott m2000, and Primera ICEPlex). b PPV, positive predictive value. c NPV, negative predictive value. d Toxigenic culture was defined by the authors as growth on cycloserine cefoxitin fructose agar (CCFA) or Cdiff CHROMagar (bioMérieux, France) confirmed with toxin gene PCR. e Composite standard defined by the authors as a positive result for both Meridian illumigene and positive by another enzyme immunoassay. f C. Diff Quik Chek Complete kit (Alere GmBH, Kolm, Germany) and DNA hybridization assay (Hain Lifescience GmBH, Nehren, Germany). g NA, nonapplicable.

Techniques: Cytotoxicity Assay, Multiplex Assay, Amplification, Helicase-dependent Amplification, Hybridization, Luminex, Nested PCR