bms ccr2 22 Search Results


bms ccr2 22  (MedChemExpress)
94
MedChemExpress bms ccr2 22
Transwell invasion assays using Py8119 ( A ) and 4T1 ( B ) breast cancer cells were performed using 1% serum pooled from three mice per group (young RAGE⁺/⁺, aged RAGE⁺/⁺, or aged RAGE −/− ) as the chemoattractant, and invasion was quantified after 24 h. Transwell assays assessing migration ( C ) and invasion ( D ) of Py8119 cells toward 1% serum pooled from aged RAGE⁺/⁺ mice ( n = 3) were performed in the presence of the RAGE inhibitor TTP488 (1 μM), the S100A8/9 inhibitor paquinimod (25 μM), the CCR1 inhibitor BX471 (10 μM), or the <t>CCR2</t> <t>inhibitor</t> <t>BMS-CCR2-22</t> (10 μM). Data represent mean ± SEM from four independent biological experiments. Statistical analysis: one-way ANOVA with Dunnett’s multiple-comparisons test. * p < 0.05; ** p < 0.01; *** p < 0.001; and **** p < 0.0001.
Bms Ccr2 22, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/bms+ccr2+22/BMS+CCR2+22/pmc13179327-331-42-43
Average 94 stars, based on 1 article reviews
bms ccr2 22 - by Bioz Stars, 2026-09
94/100 stars
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bms ccr2 22  (MuseChem Chemicals)
N/A
BMS CCR2 22（Cat No.:I010705）is a potent and selective small-molecule antagonist of the C-C chemokine receptor type 2 (CCR2), a receptor involved in monocyte recruitment, inflammation, and tumor progression. By blocking CCR2 signaling, this compound interferes
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bms 22  (Tocris)
93
Tocris bms 22
Transwell invasion assays using Py8119 ( A ) and 4T1 ( B ) breast cancer cells were performed using 1% serum pooled from three mice per group (young RAGE⁺/⁺, aged RAGE⁺/⁺, or aged RAGE −/− ) as the chemoattractant, and invasion was quantified after 24 h. Transwell assays assessing migration ( C ) and invasion ( D ) of Py8119 cells toward 1% serum pooled from aged RAGE⁺/⁺ mice ( n = 3) were performed in the presence of the RAGE inhibitor TTP488 (1 μM), the S100A8/9 inhibitor paquinimod (25 μM), the CCR1 inhibitor BX471 (10 μM), or the <t>CCR2</t> <t>inhibitor</t> <t>BMS-CCR2-22</t> (10 μM). Data represent mean ± SEM from four independent biological experiments. Statistical analysis: one-way ANOVA with Dunnett’s multiple-comparisons test. * p < 0.05; ** p < 0.01; *** p < 0.001; and **** p < 0.0001.
Bms 22, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/bms+ccr2+22/BMS+CCR2+22/pmc06258344-148-5-9
Average 93 stars, based on 1 article reviews
bms 22 - by Bioz Stars, 2026-09
93/100 stars
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ccr2 antagonist  (Tocris)
93
Tocris ccr2 antagonist
Transwell invasion assays using Py8119 ( A ) and 4T1 ( B ) breast cancer cells were performed using 1% serum pooled from three mice per group (young RAGE⁺/⁺, aged RAGE⁺/⁺, or aged RAGE −/− ) as the chemoattractant, and invasion was quantified after 24 h. Transwell assays assessing migration ( C ) and invasion ( D ) of Py8119 cells toward 1% serum pooled from aged RAGE⁺/⁺ mice ( n = 3) were performed in the presence of the RAGE inhibitor TTP488 (1 μM), the S100A8/9 inhibitor paquinimod (25 μM), the CCR1 inhibitor BX471 (10 μM), or the <t>CCR2</t> <t>inhibitor</t> <t>BMS-CCR2-22</t> (10 μM). Data represent mean ± SEM from four independent biological experiments. Statistical analysis: one-way ANOVA with Dunnett’s multiple-comparisons test. * p < 0.05; ** p < 0.01; *** p < 0.001; and **** p < 0.0001.
Ccr2 Antagonist, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/bms+ccr2+22/BMS+CCR2+22/pm40858671-54-43-48
Average 93 stars, based on 1 article reviews
ccr2 antagonist - by Bioz Stars, 2026-09
93/100 stars
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bms ccr2 22  (Aladdin Scientific Corporation)
N/A
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bms ccr2 22  (BOC Sciences)
N/A
High affinity, potent CCR2 antagonist
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bms ccr2 22  (TargetMol)
N/A
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Image Search Results


Transwell invasion assays using Py8119 ( A ) and 4T1 ( B ) breast cancer cells were performed using 1% serum pooled from three mice per group (young RAGE⁺/⁺, aged RAGE⁺/⁺, or aged RAGE −/− ) as the chemoattractant, and invasion was quantified after 24 h. Transwell assays assessing migration ( C ) and invasion ( D ) of Py8119 cells toward 1% serum pooled from aged RAGE⁺/⁺ mice ( n = 3) were performed in the presence of the RAGE inhibitor TTP488 (1 μM), the S100A8/9 inhibitor paquinimod (25 μM), the CCR1 inhibitor BX471 (10 μM), or the CCR2 inhibitor BMS-CCR2-22 (10 μM). Data represent mean ± SEM from four independent biological experiments. Statistical analysis: one-way ANOVA with Dunnett’s multiple-comparisons test. * p < 0.05; ** p < 0.01; *** p < 0.001; and **** p < 0.0001.

Journal: Communications Biology

Article Title: Aging promotes a RAGE-dependent increase in breast cancer metastasis

doi: 10.1038/s42003-026-10022-4

Figure Lengend Snippet: Transwell invasion assays using Py8119 ( A ) and 4T1 ( B ) breast cancer cells were performed using 1% serum pooled from three mice per group (young RAGE⁺/⁺, aged RAGE⁺/⁺, or aged RAGE −/− ) as the chemoattractant, and invasion was quantified after 24 h. Transwell assays assessing migration ( C ) and invasion ( D ) of Py8119 cells toward 1% serum pooled from aged RAGE⁺/⁺ mice ( n = 3) were performed in the presence of the RAGE inhibitor TTP488 (1 μM), the S100A8/9 inhibitor paquinimod (25 μM), the CCR1 inhibitor BX471 (10 μM), or the CCR2 inhibitor BMS-CCR2-22 (10 μM). Data represent mean ± SEM from four independent biological experiments. Statistical analysis: one-way ANOVA with Dunnett’s multiple-comparisons test. * p < 0.05; ** p < 0.01; *** p < 0.001; and **** p < 0.0001.

Article Snippet: Where indicated, inhibitors were added directly to both upper and lower chambers at the time of plating: 1 μM TTP488 (MedChemExpress) for RAGE inhibition, 25 μM Paquinimod (Cayman Chemicals) for S100A8/9 blockade, 10 μM BX471 (MedChemExpress) for CCR1 inhibition, or 10 μM BMS-CCR2-22 (MedChemExpress) for CCR2 inhibition.

Techniques: Migration