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Image Search Results


Sensitivity of BI 894999.

Journal: British Journal of Cancer

Article Title: Therapeutic impact of BET inhibitor BI 894999 treatment: backtranslation from the clinic

doi: 10.1038/s41416-022-01815-5

Figure Lengend Snippet: Sensitivity of BI 894999.

Article Snippet: GSK525762 (I-BET762) and CCS1477 were purchased from Chemie Tek, Indianapolis, USA; NEO2734, A485 and Romidepsin were purchased from SelleckChem.

Techniques: Binding Assay

Libraries screened for senolytic activity and identified classes of senolytics.

Journal: Aging Cell

Article Title: Strategies for senolytic drug discovery

doi: 10.1111/acel.13948

Figure Lengend Snippet: Libraries screened for senolytic activity and identified classes of senolytics.

Article Snippet: BET family protein degraders , ARV825, I‐BET151, I‐BET762, JQ1, OTX015, PFI‐1 , TAKEDA drug discovery library ( n = 47,000) , IMR‐90 fibroblasts induced by oncogenic H‐Ras expression , Wakita et al. ( ) .

Techniques: Activity Assay, Drug discovery, Expressing