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Thorlabs
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Thorlabs
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Coherent Corp
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Chondrex Inc
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Photometrics Inc
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Verlag GmbH
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IDEX
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MKS Instruments
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VISITRON Inc
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Layertec GmbH
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AHF analysentechnik
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AHF analysentechnik
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Image Search Results
Journal: Optics Express
Article Title: Side-view holographic endomicroscopy via a custom-terminated multimode fibre
doi: 10.1364/oe.426235
Figure Lengend Snippet: Fig. 2. Optical setup for both straight- and side-view imaging probes. The calibration units are used to acquire the transmission matrix of each probe prior imaging. Following the calibration, a series of holograms is applied to a digital micromirror device, shaping the incoming laser beam. The modified wavefronts are coupled into the proximal fibre facet, which translates into focal points scanned across the distal end of the probe. Through the same fibre facet, the fluorescence signals emitted by a distal object are collected and detected by a photomultiplier tube on the proximal side, allowing reconstruction of an image. Legend: MMF, multimode fibre; DMD, digital micromirror device; ID, iris diaphragm; L, lens; HWP, half-wave plate; QWP, quarter-wave plate; BS, non-polarizing beamsplitter plate; PBS, polarizing beamsplitter cube; MO, microscope objective; Cam, camera; S, shutter; OI, optical isolator; M, mirror; DM, dichroic mirror; F, filter; PMT, photomultiplier tube detector. The detailed list of components can be found in the Appendix.
Article Snippet: Appendix The equipment and components used in this work are detailed as follows (refer to Fig. 2): Laser – Coherent Sapphire SF 488; OI – free-space optical isolator: Thorlabs IO-3-488-HP; HWP1, HWP2, HWP3, HWP4 – half-wave plate: Edmund multiple order M-17.5-D-.500-B-488; QWP1, QWP2, QWP3 – quarter-wave plate: Thorlabs WPMH10M-488; PBS1, PBS2 – polarizing beamsplitter cube: Thorlabs CCM1-PBS251/M; BS1,
Techniques: Imaging, Transmission Assay, Modification, Fluorescence, Microscopy
Journal: Advanced Materials (Deerfield Beach, Fla.)
Article Title: Safe and Localized Lentiviral Gene Delivery via Injectable Mesoporous Scaffolds for Potent Antitumor Immunity
doi: 10.1002/adma.202516661
Figure Lengend Snippet: Alteration of the TME following LVP‐based scaffold vaccination combined with PD‐1 blockade. (a) Experimental design: Mice bearing B16‐OVA tumors were treated with the LVP‐based scaffold vaccine (Vax) on days 5 and 12 post‐tumor inoculation in combination with anti‐PD1 antibody administration ( n = 4 for the untreated group, n = 5 for the Vax+a‐PD1 group). (b) Tumor volumes were measured over time to assess the treatment efficacy. (c) Frequencies of Foxp3 + Tregs within the TME. (d, e) Quantification of tumor‐infiltrating CD4 + (d) and CD8 + (e) T cells per milligram of tumor tissue. (f) M1/M2 macrophage polarization was assessed by the ratio of CD86 to CD206 expression within the F4/80 + macrophage population. (g, h) Concentrations of anti‐OVA IgG1 and IgG2a antibodies in the serum of the mice at the study endpoint. The data in panels (b–h) are presented as the means ± SDs. Statistical analysis was performed using an unpaired Student's t test. p < 0.05 was considered statistically significant.
Article Snippet: The levels of
Techniques: Expressing