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Image Search Results
Journal: BMJ Open
Article Title: Vaccination assessments using the Demographic and Health Survey, 2005–2018: a scoping review
doi: 10.1136/bmjopen-2020-039693
Figure Lengend Snippet: List of papers included in a scoping review of studies assessing vaccination status using the Demographic and Health Survey (DHS)
Article Snippet:
Techniques:
Journal: Frontiers in Immunology
Article Title: C1q reprograms innate immune memory
doi: 10.3389/fimmu.2025.1515127
Figure Lengend Snippet: Single nucleotide polymorphisms in the proximity of genes encoding C1q components associate with innate immune memory responses. (A) Schematic representation of the in-vitro training experiments followed by QTL analysis using single nucleotide polymorphism (SNP) genotypes of volunteers of the 300BCG cohort. (B) Heatmap of SNPs that show a significant association with the capacity of β-glucan/BCG-induced trained immunity ( n = 267 donors). Beta shows the direction of the effect (positive = SNP increases the fold change of cytokine production upon training, and negative = SNP decreases the fold change of cytokine production). (C) Associations of SNPs rs294179, rs1561624 near C1q with the cytokine responses after 24h restimulation with LPS (10 ng/ml), 5 days after β-glucan training ( n = 267 donors). Boxplots show the genotype stratified fold changes in IL-6 and TNF responses for SNPs rs294179 and rs1561624. (D) Associations of SNPs rs666656, and rs913243 near C1q with the cytokine responses after 24h restimulation with LPS (10 ng/ml), 5 days after BCG training ( n = 267 donors). Boxplots show the genotype stratified fold changes in IL-6 and TNF responses for SNPs rs666656 and rs913243. (E) Schematic representation of the in-vivo training experiments followed by QTL analysis using SNP genotypes of volunteers of the 300BCG cohort. (F) Heatmap of SNPs that show a significant association with the capacity of the BCG vaccine-induced trained immunity ( n = 278 donors). Beta shows the direction of the effect (positive = SNP increases the fold change of cytokine production upon training, negative = SNP decreases the fold change of cytokine production) (G) Associations of SNPs rs10917276 and rs79073090 near C1q with the cytokine responses after vaccination with Bacillus Calmette–Guérin (BCG) vaccine ( n = 278 donors). Boxplots show the genotype stratified fold changes in IL-1β and TNF responses for SNPs rs10917276 and rs79073090, respectively.
Article Snippet: Individuals from the 300BCG cohort were vaccinated with 0.1 ml of
Techniques: In Vitro, In Vivo