b-0721 Search Results


fingolimod phosphate  (Echelon Biosciences)
90
Echelon Biosciences fingolimod phosphate
F-actin structure in rat astrocytes (confluent culture) treated with S1P, recombinant human plasma gelsolin and <t>FTY720P,</t> or their combination. At 8 hours incubation the cells were fixed with 4% paraformaldehyde, permeabilized with Triton X-100 and F-actin was stained with Phalloidin-FITC. Arrows indicate gaps in astrocyte monolayers. Data from one representative experiment are shown (A) . B shows quantitative analysis of F-actin fluorescence in the astrocyte monolayer under treatment, indicated by numbers 1 to 10 in the left lower corner of each picture. *Significantly different. Error bars represent standard error of the mean. S1P – sphingosine – 1– phosphate, GSN – recombinant human plasma gelsolin.
Fingolimod Phosphate, supplied by Echelon Biosciences, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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fingolimod phosphate - by Bioz Stars, 2026-03
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F-actin structure in rat astrocytes (confluent culture) treated with S1P, recombinant human plasma gelsolin and FTY720P, or their combination. At 8 hours incubation the cells were fixed with 4% paraformaldehyde, permeabilized with Triton X-100 and F-actin was stained with Phalloidin-FITC. Arrows indicate gaps in astrocyte monolayers. Data from one representative experiment are shown (A) . B shows quantitative analysis of F-actin fluorescence in the astrocyte monolayer under treatment, indicated by numbers 1 to 10 in the left lower corner of each picture. *Significantly different. Error bars represent standard error of the mean. S1P – sphingosine – 1– phosphate, GSN – recombinant human plasma gelsolin.

Journal: Journal of Neuroinflammation

Article Title: Increased levels of sphingosine-1-phosphate in cerebrospinal fluid of patients diagnosed with tick-borne encephalitis

doi: 10.1186/s12974-014-0193-4

Figure Lengend Snippet: F-actin structure in rat astrocytes (confluent culture) treated with S1P, recombinant human plasma gelsolin and FTY720P, or their combination. At 8 hours incubation the cells were fixed with 4% paraformaldehyde, permeabilized with Triton X-100 and F-actin was stained with Phalloidin-FITC. Arrows indicate gaps in astrocyte monolayers. Data from one representative experiment are shown (A) . B shows quantitative analysis of F-actin fluorescence in the astrocyte monolayer under treatment, indicated by numbers 1 to 10 in the left lower corner of each picture. *Significantly different. Error bars represent standard error of the mean. S1P – sphingosine – 1– phosphate, GSN – recombinant human plasma gelsolin.

Article Snippet: S1P (S9666) was purchased from Sigma Aldrich (St Louis, Missouri, United States). (S)- fingolimod phosphate (FTY720P; B-0721) was purchased from Echelon Biosciences Inc. (Salt Lake City, Utah, United States).

Techniques: Recombinant, Incubation, Staining, Fluorescence

S1P, recombinant human plasma gelsolin (rhGSN) and FTY720P prevent release of IL-6 from rat astrocytes. IL-6 release from rat astrocytes 8 hours after addition of S1P, (rhGSN and FTY720P (A) . Decrease of IL-6 release from rat astrocytes activated with S1P (5 μM) in the presence of rhGSN (5 μM) and FTY720P (5 μM) (B) . *Significantly different. Error bars represent standard deviation of the mean. IL–6 – interleukin 6, S1P – shingosine-1-phosphate

Journal: Journal of Neuroinflammation

Article Title: Increased levels of sphingosine-1-phosphate in cerebrospinal fluid of patients diagnosed with tick-borne encephalitis

doi: 10.1186/s12974-014-0193-4

Figure Lengend Snippet: S1P, recombinant human plasma gelsolin (rhGSN) and FTY720P prevent release of IL-6 from rat astrocytes. IL-6 release from rat astrocytes 8 hours after addition of S1P, (rhGSN and FTY720P (A) . Decrease of IL-6 release from rat astrocytes activated with S1P (5 μM) in the presence of rhGSN (5 μM) and FTY720P (5 μM) (B) . *Significantly different. Error bars represent standard deviation of the mean. IL–6 – interleukin 6, S1P – shingosine-1-phosphate

Article Snippet: S1P (S9666) was purchased from Sigma Aldrich (St Louis, Missouri, United States). (S)- fingolimod phosphate (FTY720P; B-0721) was purchased from Echelon Biosciences Inc. (Salt Lake City, Utah, United States).

Techniques: Recombinant, Standard Deviation