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Preclin Biosystems
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Treston Inc
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N/A
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AZD 1152 HQPA is an inhibitor of Aurora kinase B IC 0 37 nM that demonstrates 3 700 fold greater selectivity for Aurora kinase B over Aurora kinase A IC 1 368 µM It does
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N/A
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AZD1152-HQPA is the active metabolite of AZD-1152, AZD1152-HQPA (Barasertib) is a highly selective Aurora B inhibitor with IC50 of 0.37 nM, ~100 fold more selective for Aurora B over Aurora A.A highly selective ARK-2 inhibitor
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Image Search Results
Journal: Bioinformatics
Article Title: Benchmarking substrate-based kinase activity inference using phosphoproteomic data
doi: 10.1093/bioinformatics/btx082
Figure Lengend Snippet: Human kinases displaying specific regulation—up or down—in perturbations quantified using high-throughput phosphoproteomics
Article Snippet:
Techniques: Activation Assay, Over Expression
Journal: PLoS ONE
Article Title: Evolution of Resistance to Aurora Kinase B Inhibitors in Leukaemia Cells
doi: 10.1371/journal.pone.0030734
Figure Lengend Snippet: Relative resistance of CEM/AKB4 cells to cytotoxic agents compared to parental CCRF-CEM cells.
Article Snippet:
Techniques: