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RayBiotech inc glass slide
Glass Slide, supplied by RayBiotech inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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RayBiotech inc mouse l308 quantitative microarray
Fig. 4 Tet inhibited NLRP3 inflammasome activation by canonical and non-canonical pathways in vivo. a Functional enrichment analysis with KEGG biological processes of the significant different inflammatory protein in serum identified by quantitative inflammation <t>microarray</t> from control mice and silicosis mice. The top 20 pathways with a P < 0.05 were shown with their names. b Functional enrichment analysis with KEGG biological processes of the significantly different inflammatory protein in serum identified by quantitative inflammation microarray from silicosis mice treated with or without Tet. The top 20 pathways with a P < 0.05 were shown with their names. c Functional enrichment analysis with KEGG biological processes was performed using KEGG database in Si, Si + Tet, and PBS groups of mice treated as Fig. 2a (n = 3 per group). d The Venn diagram of transcriptome and quantitative inflammation microarray analysis. The intersecting signaling pathways were listed in the table in Fig. 4e. f-h The mRNA levels of TLR4, MyD88, and Caspase-11 of murine lung tissue in four groups (PBS + Vehicle, PBS + Tet, Si + Vehicle, and Si + Tet groups) treated as Fig. 2a (n = 9 per group). i Western blots of TLR4, MyD88, Pro-Caspase-11 and Cleaved Caspase-11 of murine lung tissue treated as (f). j Statistical analysis of band densities from images in (i). The data are reported as the mean ± SEM. Significance for each figure: **P < 0.01, ***P < 0.001 and ns indicates not significant.
Mouse L308 Quantitative Microarray, supplied by RayBiotech inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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RayBiotech inc raybio cytokine antibody arrays
Fig. 4 Tet inhibited NLRP3 inflammasome activation by canonical and non-canonical pathways in vivo. a Functional enrichment analysis with KEGG biological processes of the significant different inflammatory protein in serum identified by quantitative inflammation <t>microarray</t> from control mice and silicosis mice. The top 20 pathways with a P < 0.05 were shown with their names. b Functional enrichment analysis with KEGG biological processes of the significantly different inflammatory protein in serum identified by quantitative inflammation microarray from silicosis mice treated with or without Tet. The top 20 pathways with a P < 0.05 were shown with their names. c Functional enrichment analysis with KEGG biological processes was performed using KEGG database in Si, Si + Tet, and PBS groups of mice treated as Fig. 2a (n = 3 per group). d The Venn diagram of transcriptome and quantitative inflammation microarray analysis. The intersecting signaling pathways were listed in the table in Fig. 4e. f-h The mRNA levels of TLR4, MyD88, and Caspase-11 of murine lung tissue in four groups (PBS + Vehicle, PBS + Tet, Si + Vehicle, and Si + Tet groups) treated as Fig. 2a (n = 9 per group). i Western blots of TLR4, MyD88, Pro-Caspase-11 and Cleaved Caspase-11 of murine lung tissue treated as (f). j Statistical analysis of band densities from images in (i). The data are reported as the mean ± SEM. Significance for each figure: **P < 0.01, ***P < 0.001 and ns indicates not significant.
Raybio Cytokine Antibody Arrays, supplied by RayBiotech inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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RayBiotech inc biotin label based rat antibody array 1
Fig. 4 Tet inhibited NLRP3 inflammasome activation by canonical and non-canonical pathways in vivo. a Functional enrichment analysis with KEGG biological processes of the significant different inflammatory protein in serum identified by quantitative inflammation <t>microarray</t> from control mice and silicosis mice. The top 20 pathways with a P < 0.05 were shown with their names. b Functional enrichment analysis with KEGG biological processes of the significantly different inflammatory protein in serum identified by quantitative inflammation microarray from silicosis mice treated with or without Tet. The top 20 pathways with a P < 0.05 were shown with their names. c Functional enrichment analysis with KEGG biological processes was performed using KEGG database in Si, Si + Tet, and PBS groups of mice treated as Fig. 2a (n = 3 per group). d The Venn diagram of transcriptome and quantitative inflammation microarray analysis. The intersecting signaling pathways were listed in the table in Fig. 4e. f-h The mRNA levels of TLR4, MyD88, and Caspase-11 of murine lung tissue in four groups (PBS + Vehicle, PBS + Tet, Si + Vehicle, and Si + Tet groups) treated as Fig. 2a (n = 9 per group). i Western blots of TLR4, MyD88, Pro-Caspase-11 and Cleaved Caspase-11 of murine lung tissue treated as (f). j Statistical analysis of band densities from images in (i). The data are reported as the mean ± SEM. Significance for each figure: **P < 0.01, ***P < 0.001 and ns indicates not significant.
Biotin Label Based Rat Antibody Array 1, supplied by RayBiotech inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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CombiMatrix human cancer 3711 electrasense 4×2 k array slides
Fig. 4 Tet inhibited NLRP3 inflammasome activation by canonical and non-canonical pathways in vivo. a Functional enrichment analysis with KEGG biological processes of the significant different inflammatory protein in serum identified by quantitative inflammation <t>microarray</t> from control mice and silicosis mice. The top 20 pathways with a P < 0.05 were shown with their names. b Functional enrichment analysis with KEGG biological processes of the significantly different inflammatory protein in serum identified by quantitative inflammation microarray from silicosis mice treated with or without Tet. The top 20 pathways with a P < 0.05 were shown with their names. c Functional enrichment analysis with KEGG biological processes was performed using KEGG database in Si, Si + Tet, and PBS groups of mice treated as Fig. 2a (n = 3 per group). d The Venn diagram of transcriptome and quantitative inflammation microarray analysis. The intersecting signaling pathways were listed in the table in Fig. 4e. f-h The mRNA levels of TLR4, MyD88, and Caspase-11 of murine lung tissue in four groups (PBS + Vehicle, PBS + Tet, Si + Vehicle, and Si + Tet groups) treated as Fig. 2a (n = 9 per group). i Western blots of TLR4, MyD88, Pro-Caspase-11 and Cleaved Caspase-11 of murine lung tissue treated as (f). j Statistical analysis of band densities from images in (i). The data are reported as the mean ± SEM. Significance for each figure: **P < 0.01, ***P < 0.001 and ns indicates not significant.
Human Cancer 3711 Electrasense 4×2 K Array Slides, supplied by CombiMatrix, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Hamamatsu 4 tissue micro-array (tma) slides
Fig. 4 Tet inhibited NLRP3 inflammasome activation by canonical and non-canonical pathways in vivo. a Functional enrichment analysis with KEGG biological processes of the significant different inflammatory protein in serum identified by quantitative inflammation <t>microarray</t> from control mice and silicosis mice. The top 20 pathways with a P < 0.05 were shown with their names. b Functional enrichment analysis with KEGG biological processes of the significantly different inflammatory protein in serum identified by quantitative inflammation microarray from silicosis mice treated with or without Tet. The top 20 pathways with a P < 0.05 were shown with their names. c Functional enrichment analysis with KEGG biological processes was performed using KEGG database in Si, Si + Tet, and PBS groups of mice treated as Fig. 2a (n = 3 per group). d The Venn diagram of transcriptome and quantitative inflammation microarray analysis. The intersecting signaling pathways were listed in the table in Fig. 4e. f-h The mRNA levels of TLR4, MyD88, and Caspase-11 of murine lung tissue in four groups (PBS + Vehicle, PBS + Tet, Si + Vehicle, and Si + Tet groups) treated as Fig. 2a (n = 9 per group). i Western blots of TLR4, MyD88, Pro-Caspase-11 and Cleaved Caspase-11 of murine lung tissue treated as (f). j Statistical analysis of band densities from images in (i). The data are reported as the mean ± SEM. Significance for each figure: **P < 0.01, ***P < 0.001 and ns indicates not significant.
4 Tissue Micro Array (Tma) Slides, supplied by Hamamatsu, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Cosmo Bio USA tissue array slide cb-a712
Fig. 4 Tet inhibited NLRP3 inflammasome activation by canonical and non-canonical pathways in vivo. a Functional enrichment analysis with KEGG biological processes of the significant different inflammatory protein in serum identified by quantitative inflammation <t>microarray</t> from control mice and silicosis mice. The top 20 pathways with a P < 0.05 were shown with their names. b Functional enrichment analysis with KEGG biological processes of the significantly different inflammatory protein in serum identified by quantitative inflammation microarray from silicosis mice treated with or without Tet. The top 20 pathways with a P < 0.05 were shown with their names. c Functional enrichment analysis with KEGG biological processes was performed using KEGG database in Si, Si + Tet, and PBS groups of mice treated as Fig. 2a (n = 3 per group). d The Venn diagram of transcriptome and quantitative inflammation microarray analysis. The intersecting signaling pathways were listed in the table in Fig. 4e. f-h The mRNA levels of TLR4, MyD88, and Caspase-11 of murine lung tissue in four groups (PBS + Vehicle, PBS + Tet, Si + Vehicle, and Si + Tet groups) treated as Fig. 2a (n = 9 per group). i Western blots of TLR4, MyD88, Pro-Caspase-11 and Cleaved Caspase-11 of murine lung tissue treated as (f). j Statistical analysis of band densities from images in (i). The data are reported as the mean ± SEM. Significance for each figure: **P < 0.01, ***P < 0.001 and ns indicates not significant.
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JPT Peptide Technologies GmbH array slides
Fig. 4 Tet inhibited NLRP3 inflammasome activation by canonical and non-canonical pathways in vivo. a Functional enrichment analysis with KEGG biological processes of the significant different inflammatory protein in serum identified by quantitative inflammation <t>microarray</t> from control mice and silicosis mice. The top 20 pathways with a P < 0.05 were shown with their names. b Functional enrichment analysis with KEGG biological processes of the significantly different inflammatory protein in serum identified by quantitative inflammation microarray from silicosis mice treated with or without Tet. The top 20 pathways with a P < 0.05 were shown with their names. c Functional enrichment analysis with KEGG biological processes was performed using KEGG database in Si, Si + Tet, and PBS groups of mice treated as Fig. 2a (n = 3 per group). d The Venn diagram of transcriptome and quantitative inflammation microarray analysis. The intersecting signaling pathways were listed in the table in Fig. 4e. f-h The mRNA levels of TLR4, MyD88, and Caspase-11 of murine lung tissue in four groups (PBS + Vehicle, PBS + Tet, Si + Vehicle, and Si + Tet groups) treated as Fig. 2a (n = 9 per group). i Western blots of TLR4, MyD88, Pro-Caspase-11 and Cleaved Caspase-11 of murine lung tissue treated as (f). j Statistical analysis of band densities from images in (i). The data are reported as the mean ± SEM. Significance for each figure: **P < 0.01, ***P < 0.001 and ns indicates not significant.
Array Slides, supplied by JPT Peptide Technologies GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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TissueArray.com LLC human tissue array slides
Fig. 4 Tet inhibited NLRP3 inflammasome activation by canonical and non-canonical pathways in vivo. a Functional enrichment analysis with KEGG biological processes of the significant different inflammatory protein in serum identified by quantitative inflammation <t>microarray</t> from control mice and silicosis mice. The top 20 pathways with a P < 0.05 were shown with their names. b Functional enrichment analysis with KEGG biological processes of the significantly different inflammatory protein in serum identified by quantitative inflammation microarray from silicosis mice treated with or without Tet. The top 20 pathways with a P < 0.05 were shown with their names. c Functional enrichment analysis with KEGG biological processes was performed using KEGG database in Si, Si + Tet, and PBS groups of mice treated as Fig. 2a (n = 3 per group). d The Venn diagram of transcriptome and quantitative inflammation microarray analysis. The intersecting signaling pathways were listed in the table in Fig. 4e. f-h The mRNA levels of TLR4, MyD88, and Caspase-11 of murine lung tissue in four groups (PBS + Vehicle, PBS + Tet, Si + Vehicle, and Si + Tet groups) treated as Fig. 2a (n = 9 per group). i Western blots of TLR4, MyD88, Pro-Caspase-11 and Cleaved Caspase-11 of murine lung tissue treated as (f). j Statistical analysis of band densities from images in (i). The data are reported as the mean ± SEM. Significance for each figure: **P < 0.01, ***P < 0.001 and ns indicates not significant.
Human Tissue Array Slides, supplied by TissueArray.com LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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SuperBioChips tissue array slides cj2
Fig. 4 Tet inhibited NLRP3 inflammasome activation by canonical and non-canonical pathways in vivo. a Functional enrichment analysis with KEGG biological processes of the significant different inflammatory protein in serum identified by quantitative inflammation <t>microarray</t> from control mice and silicosis mice. The top 20 pathways with a P < 0.05 were shown with their names. b Functional enrichment analysis with KEGG biological processes of the significantly different inflammatory protein in serum identified by quantitative inflammation microarray from silicosis mice treated with or without Tet. The top 20 pathways with a P < 0.05 were shown with their names. c Functional enrichment analysis with KEGG biological processes was performed using KEGG database in Si, Si + Tet, and PBS groups of mice treated as Fig. 2a (n = 3 per group). d The Venn diagram of transcriptome and quantitative inflammation microarray analysis. The intersecting signaling pathways were listed in the table in Fig. 4e. f-h The mRNA levels of TLR4, MyD88, and Caspase-11 of murine lung tissue in four groups (PBS + Vehicle, PBS + Tet, Si + Vehicle, and Si + Tet groups) treated as Fig. 2a (n = 9 per group). i Western blots of TLR4, MyD88, Pro-Caspase-11 and Cleaved Caspase-11 of murine lung tissue treated as (f). j Statistical analysis of band densities from images in (i). The data are reported as the mean ± SEM. Significance for each figure: **P < 0.01, ***P < 0.001 and ns indicates not significant.
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SuperBioChips deparaffinized tissue array slide
Fig. 4 Tet inhibited NLRP3 inflammasome activation by canonical and non-canonical pathways in vivo. a Functional enrichment analysis with KEGG biological processes of the significant different inflammatory protein in serum identified by quantitative inflammation <t>microarray</t> from control mice and silicosis mice. The top 20 pathways with a P < 0.05 were shown with their names. b Functional enrichment analysis with KEGG biological processes of the significantly different inflammatory protein in serum identified by quantitative inflammation microarray from silicosis mice treated with or without Tet. The top 20 pathways with a P < 0.05 were shown with their names. c Functional enrichment analysis with KEGG biological processes was performed using KEGG database in Si, Si + Tet, and PBS groups of mice treated as Fig. 2a (n = 3 per group). d The Venn diagram of transcriptome and quantitative inflammation microarray analysis. The intersecting signaling pathways were listed in the table in Fig. 4e. f-h The mRNA levels of TLR4, MyD88, and Caspase-11 of murine lung tissue in four groups (PBS + Vehicle, PBS + Tet, Si + Vehicle, and Si + Tet groups) treated as Fig. 2a (n = 9 per group). i Western blots of TLR4, MyD88, Pro-Caspase-11 and Cleaved Caspase-11 of murine lung tissue treated as (f). j Statistical analysis of band densities from images in (i). The data are reported as the mean ± SEM. Significance for each figure: **P < 0.01, ***P < 0.001 and ns indicates not significant.
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Image Search Results


Fig. 4 Tet inhibited NLRP3 inflammasome activation by canonical and non-canonical pathways in vivo. a Functional enrichment analysis with KEGG biological processes of the significant different inflammatory protein in serum identified by quantitative inflammation microarray from control mice and silicosis mice. The top 20 pathways with a P < 0.05 were shown with their names. b Functional enrichment analysis with KEGG biological processes of the significantly different inflammatory protein in serum identified by quantitative inflammation microarray from silicosis mice treated with or without Tet. The top 20 pathways with a P < 0.05 were shown with their names. c Functional enrichment analysis with KEGG biological processes was performed using KEGG database in Si, Si + Tet, and PBS groups of mice treated as Fig. 2a (n = 3 per group). d The Venn diagram of transcriptome and quantitative inflammation microarray analysis. The intersecting signaling pathways were listed in the table in Fig. 4e. f-h The mRNA levels of TLR4, MyD88, and Caspase-11 of murine lung tissue in four groups (PBS + Vehicle, PBS + Tet, Si + Vehicle, and Si + Tet groups) treated as Fig. 2a (n = 9 per group). i Western blots of TLR4, MyD88, Pro-Caspase-11 and Cleaved Caspase-11 of murine lung tissue treated as (f). j Statistical analysis of band densities from images in (i). The data are reported as the mean ± SEM. Significance for each figure: **P < 0.01, ***P < 0.001 and ns indicates not significant.

Journal: Acta pharmacologica Sinica

Article Title: Tetrandrine alleviates silicosis by inhibiting canonical and non-canonical NLRP3 inflammasome activation in lung macrophages.

doi: 10.1038/s41401-021-00693-6

Figure Lengend Snippet: Fig. 4 Tet inhibited NLRP3 inflammasome activation by canonical and non-canonical pathways in vivo. a Functional enrichment analysis with KEGG biological processes of the significant different inflammatory protein in serum identified by quantitative inflammation microarray from control mice and silicosis mice. The top 20 pathways with a P < 0.05 were shown with their names. b Functional enrichment analysis with KEGG biological processes of the significantly different inflammatory protein in serum identified by quantitative inflammation microarray from silicosis mice treated with or without Tet. The top 20 pathways with a P < 0.05 were shown with their names. c Functional enrichment analysis with KEGG biological processes was performed using KEGG database in Si, Si + Tet, and PBS groups of mice treated as Fig. 2a (n = 3 per group). d The Venn diagram of transcriptome and quantitative inflammation microarray analysis. The intersecting signaling pathways were listed in the table in Fig. 4e. f-h The mRNA levels of TLR4, MyD88, and Caspase-11 of murine lung tissue in four groups (PBS + Vehicle, PBS + Tet, Si + Vehicle, and Si + Tet groups) treated as Fig. 2a (n = 9 per group). i Western blots of TLR4, MyD88, Pro-Caspase-11 and Cleaved Caspase-11 of murine lung tissue treated as (f). j Statistical analysis of band densities from images in (i). The data are reported as the mean ± SEM. Significance for each figure: **P < 0.01, ***P < 0.001 and ns indicates not significant.

Article Snippet: The profiles of 308 cytokines in serum of mice in blank PBS group, silica group and silica + Tet group were simultaneously detected using a mouse L308 quantitative microarray (AAM-BLG1-4, RayBiotech, Guangzhou, China) according to the manufacturer’s instructions.

Techniques: Activation Assay, In Vivo, Functional Assay, Microarray, Control, Protein-Protein interactions, Western Blot