antiangiogenic agents Search Results


recombinant endostatin  (MedChemExpress)
94
MedChemExpress recombinant endostatin
(A) Representative immunofluorescence images showing VEGF expression in the femoral head of control and SONFH groups (scale bar = 100 μm); (B) Quantification of VEGF fluorescence intensity in control and SONFH groups; (C) Representative immunofluorescence images showing <t>Endostatin</t> expression in the femoral head of control and SONFH groups (scale bar = 100 μm); (D) Quantification of Endostatin fluorescence intensity in these two groups; (E) Representative Western blotting images of MMP-2 expression in the femoral head of control and SONFH groups; (F) Quantification of MMP-2 expression in these two groups. (*P < 0.05, **P < 0.01).
Recombinant Endostatin, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/antiangiogenic+agents/Collagen+alpha-1(XVIII)+chain%2FCOL18A1%2C+Mouse/pmc13089727-58-34-38
Average 94 stars, based on 1 article reviews
recombinant endostatin - by Bioz Stars, 2026-11
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type ix collagen  (ProSci Incorporated)
90
ProSci Incorporated type ix collagen
(A) Representative immunofluorescence images showing VEGF expression in the femoral head of control and SONFH groups (scale bar = 100 μm); (B) Quantification of VEGF fluorescence intensity in control and SONFH groups; (C) Representative immunofluorescence images showing <t>Endostatin</t> expression in the femoral head of control and SONFH groups (scale bar = 100 μm); (D) Quantification of Endostatin fluorescence intensity in these two groups; (E) Representative Western blotting images of MMP-2 expression in the femoral head of control and SONFH groups; (F) Quantification of MMP-2 expression in these two groups. (*P < 0.05, **P < 0.01).
Type Ix Collagen, supplied by ProSci Incorporated, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/antiangiogenic+agents/COL18A1+Antibody%2C+Monoclonal/pmc03374853-17-25-20
Average 90 stars, based on 1 article reviews
type ix collagen - by Bioz Stars, 2026-11
90/100 stars
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antiangiogenic agents  (ANGIOGENE PHARMACEUTICALS LIMITED)
90
ANGIOGENE PHARMACEUTICALS LIMITED antiangiogenic agents
(A) Representative immunofluorescence images showing VEGF expression in the femoral head of control and SONFH groups (scale bar = 100 μm); (B) Quantification of VEGF fluorescence intensity in control and SONFH groups; (C) Representative immunofluorescence images showing <t>Endostatin</t> expression in the femoral head of control and SONFH groups (scale bar = 100 μm); (D) Quantification of Endostatin fluorescence intensity in these two groups; (E) Representative Western blotting images of MMP-2 expression in the femoral head of control and SONFH groups; (F) Quantification of MMP-2 expression in these two groups. (*P < 0.05, **P < 0.01).
Antiangiogenic Agents, supplied by ANGIOGENE PHARMACEUTICALS LIMITED, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/antiangiogenic+agents/antiangiogenic+agents/pm18022556-61-23-29
Average 90 stars, based on 1 article reviews
antiangiogenic agents - by Bioz Stars, 2026-11
90/100 stars
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anti-angiogenic therapeutics  (Adamis corporation)
90
Adamis corporation anti-angiogenic therapeutics
(A) Representative immunofluorescence images showing VEGF expression in the femoral head of control and SONFH groups (scale bar = 100 μm); (B) Quantification of VEGF fluorescence intensity in control and SONFH groups; (C) Representative immunofluorescence images showing <t>Endostatin</t> expression in the femoral head of control and SONFH groups (scale bar = 100 μm); (D) Quantification of Endostatin fluorescence intensity in these two groups; (E) Representative Western blotting images of MMP-2 expression in the femoral head of control and SONFH groups; (F) Quantification of MMP-2 expression in these two groups. (*P < 0.05, **P < 0.01).
Anti Angiogenic Therapeutics, supplied by Adamis corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/antiangiogenic+agents/antiangiogenic+agents/pmc06200776__mmc2-25-6-17
Average 90 stars, based on 1 article reviews
anti-angiogenic therapeutics - by Bioz Stars, 2026-11
90/100 stars
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antiangiogenic agents ziv-aflibercept  (Regeneron inc)
90
Regeneron inc antiangiogenic agents ziv-aflibercept
(A) Representative immunofluorescence images showing VEGF expression in the femoral head of control and SONFH groups (scale bar = 100 μm); (B) Quantification of VEGF fluorescence intensity in control and SONFH groups; (C) Representative immunofluorescence images showing <t>Endostatin</t> expression in the femoral head of control and SONFH groups (scale bar = 100 μm); (D) Quantification of Endostatin fluorescence intensity in these two groups; (E) Representative Western blotting images of MMP-2 expression in the femoral head of control and SONFH groups; (F) Quantification of MMP-2 expression in these two groups. (*P < 0.05, **P < 0.01).
Antiangiogenic Agents Ziv Aflibercept, supplied by Regeneron inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/antiangiogenic+agents/antiangiogenic+agents+ziv+aflibercept/10__2147_slash_cmar__s113320-22-32-34
Average 90 stars, based on 1 article reviews
antiangiogenic agents ziv-aflibercept - by Bioz Stars, 2026-11
90/100 stars
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antiangiogenic agent avastin  (Genentech inc)
90
Genentech inc antiangiogenic agent avastin
(A) Representative immunofluorescence images showing VEGF expression in the femoral head of control and SONFH groups (scale bar = 100 μm); (B) Quantification of VEGF fluorescence intensity in control and SONFH groups; (C) Representative immunofluorescence images showing <t>Endostatin</t> expression in the femoral head of control and SONFH groups (scale bar = 100 μm); (D) Quantification of Endostatin fluorescence intensity in these two groups; (E) Representative Western blotting images of MMP-2 expression in the femoral head of control and SONFH groups; (F) Quantification of MMP-2 expression in these two groups. (*P < 0.05, **P < 0.01).
Antiangiogenic Agent Avastin, supplied by Genentech inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/antiangiogenic+agents/antiangiogenic+agent+avastin/pmc03042303-21-20-23
Average 90 stars, based on 1 article reviews
antiangiogenic agent avastin - by Bioz Stars, 2026-11
90/100 stars
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antiangiogenic agents  (MultiTarget Pharmaceuticals)
90
MultiTarget Pharmaceuticals antiangiogenic agents
(A) Representative immunofluorescence images showing VEGF expression in the femoral head of control and SONFH groups (scale bar = 100 μm); (B) Quantification of VEGF fluorescence intensity in control and SONFH groups; (C) Representative immunofluorescence images showing <t>Endostatin</t> expression in the femoral head of control and SONFH groups (scale bar = 100 μm); (D) Quantification of Endostatin fluorescence intensity in these two groups; (E) Representative Western blotting images of MMP-2 expression in the femoral head of control and SONFH groups; (F) Quantification of MMP-2 expression in these two groups. (*P < 0.05, **P < 0.01).
Antiangiogenic Agents, supplied by MultiTarget Pharmaceuticals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/antiangiogenic+agents/antiangiogenic+agents/pm37234980-61-1-0
Average 90 stars, based on 1 article reviews
antiangiogenic agents - by Bioz Stars, 2026-11
90/100 stars
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anti-angiogenic agents  (Piramal Phytocare)
90
Piramal Phytocare anti-angiogenic agents
(A) Representative immunofluorescence images showing VEGF expression in the femoral head of control and SONFH groups (scale bar = 100 μm); (B) Quantification of VEGF fluorescence intensity in control and SONFH groups; (C) Representative immunofluorescence images showing <t>Endostatin</t> expression in the femoral head of control and SONFH groups (scale bar = 100 μm); (D) Quantification of Endostatin fluorescence intensity in these two groups; (E) Representative Western blotting images of MMP-2 expression in the femoral head of control and SONFH groups; (F) Quantification of MMP-2 expression in these two groups. (*P < 0.05, **P < 0.01).
Anti Angiogenic Agents, supplied by Piramal Phytocare, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/antiangiogenic+agents/anti+angiogenic+agents/10__2147_slash_dddt__s55621-11-40-76
Average 90 stars, based on 1 article reviews
anti-angiogenic agents - by Bioz Stars, 2026-11
90/100 stars
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anti-angiogenic therapies  (Genentech inc)
90
Genentech inc anti-angiogenic therapies
(A) Representative immunofluorescence images showing VEGF expression in the femoral head of control and SONFH groups (scale bar = 100 μm); (B) Quantification of VEGF fluorescence intensity in control and SONFH groups; (C) Representative immunofluorescence images showing <t>Endostatin</t> expression in the femoral head of control and SONFH groups (scale bar = 100 μm); (D) Quantification of Endostatin fluorescence intensity in these two groups; (E) Representative Western blotting images of MMP-2 expression in the femoral head of control and SONFH groups; (F) Quantification of MMP-2 expression in these two groups. (*P < 0.05, **P < 0.01).
Anti Angiogenic Therapies, supplied by Genentech inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/antiangiogenic+agents/antiangiogenic+agents/pmc03111192-73-16-11
Average 90 stars, based on 1 article reviews
anti-angiogenic therapies - by Bioz Stars, 2026-11
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antiangiogenic agents  (Sugen Inc)
86
Sugen Inc antiangiogenic agents
(A) Representative immunofluorescence images showing VEGF expression in the femoral head of control and SONFH groups (scale bar = 100 μm); (B) Quantification of VEGF fluorescence intensity in control and SONFH groups; (C) Representative immunofluorescence images showing <t>Endostatin</t> expression in the femoral head of control and SONFH groups (scale bar = 100 μm); (D) Quantification of Endostatin fluorescence intensity in these two groups; (E) Representative Western blotting images of MMP-2 expression in the femoral head of control and SONFH groups; (F) Quantification of MMP-2 expression in these two groups. (*P < 0.05, **P < 0.01).
Antiangiogenic Agents, supplied by Sugen Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/antiangiogenic+agents/agents+antiangiogenic/10__1161_slash_jaha__125__042608-37-46-49
Average 86 stars, based on 1 article reviews
antiangiogenic agents - by Bioz Stars, 2026-11
86/100 stars
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antiangiogenic agent aflibercept  (Sanofi)
86
Sanofi antiangiogenic agent aflibercept
Effect of nicorandil (Nic) and <t>aflibercept</t> (Afl) on blood pressure. ( a ) Systolic (SBP), ( b ) diastolic (DBP), and ( c ) mean arterial pressure (MBP). Ctrl: control group, Afl: aflibercept group (10 mg/kg twice a week subcutaneously), Nic: nicorandil group (10 mg/kg/day via drinking water), and Com: combination group (aflibercept [10 mg/kg twice a week] + nicorandil [10 mg/kg/day via drinking water]). n = 6 in each group, *indicates p < 0.05 according to two-way analysis of variance (ANOVA) test.
Antiangiogenic Agent Aflibercept, supplied by Sanofi, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/antiangiogenic+agents/aflibercept+agent+antiangiogenic/pmc13128807-143-1-10
Average 86 stars, based on 1 article reviews
antiangiogenic agent aflibercept - by Bioz Stars, 2026-11
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biomimetic antiangiogenic agent  (BioMimetic Therapeutics)
90
BioMimetic Therapeutics biomimetic antiangiogenic agent
Effect of nicorandil (Nic) and <t>aflibercept</t> (Afl) on blood pressure. ( a ) Systolic (SBP), ( b ) diastolic (DBP), and ( c ) mean arterial pressure (MBP). Ctrl: control group, Afl: aflibercept group (10 mg/kg twice a week subcutaneously), Nic: nicorandil group (10 mg/kg/day via drinking water), and Com: combination group (aflibercept [10 mg/kg twice a week] + nicorandil [10 mg/kg/day via drinking water]). n = 6 in each group, *indicates p < 0.05 according to two-way analysis of variance (ANOVA) test.
Biomimetic Antiangiogenic Agent, supplied by BioMimetic Therapeutics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/antiangiogenic+agents/biomimetic+antiangiogenic+agent/10__1016_slash_j__cclet__2022__05__032-299-6-6
Average 90 stars, based on 1 article reviews
biomimetic antiangiogenic agent - by Bioz Stars, 2026-11
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Image Search Results


(A) Representative immunofluorescence images showing VEGF expression in the femoral head of control and SONFH groups (scale bar = 100 μm); (B) Quantification of VEGF fluorescence intensity in control and SONFH groups; (C) Representative immunofluorescence images showing Endostatin expression in the femoral head of control and SONFH groups (scale bar = 100 μm); (D) Quantification of Endostatin fluorescence intensity in these two groups; (E) Representative Western blotting images of MMP-2 expression in the femoral head of control and SONFH groups; (F) Quantification of MMP-2 expression in these two groups. (*P < 0.05, **P < 0.01).

Journal: PLOS One

Article Title: MMP-2 associated imbalance of VEGF/Endostatin is linked to suppression of the PI3K/AKT/HIF-1α pathway in steroid-induced osteonecrosis of femoral head

doi: 10.1371/journal.pone.0346880

Figure Lengend Snippet: (A) Representative immunofluorescence images showing VEGF expression in the femoral head of control and SONFH groups (scale bar = 100 μm); (B) Quantification of VEGF fluorescence intensity in control and SONFH groups; (C) Representative immunofluorescence images showing Endostatin expression in the femoral head of control and SONFH groups (scale bar = 100 μm); (D) Quantification of Endostatin fluorescence intensity in these two groups; (E) Representative Western blotting images of MMP-2 expression in the femoral head of control and SONFH groups; (F) Quantification of MMP-2 expression in these two groups. (*P < 0.05, **P < 0.01).

Article Snippet: Mice in the SONFH+MMP-2 group received subcutaneous injections of recombinant MMP-2 (10 μg/kg; MedChemExpress, NJ, USA) every three days [ , ], while those in the SONFH+Endostatin group were administered daily subcutaneous injections of recombinant Endostatin (2 mg/kg; MedChemExpress, NJ, USA) [ ].

Techniques: Immunofluorescence, Expressing, Control, Fluorescence, Western Blot

(A) Representative HE staining images of the femoral head in control, SONFH, and SONFH+Endostatin groups (scale bar = 100 μm); (B) Quantitative analysis of percentage of empty osteocyte from HE staining; (C) Representative micro-CT vascular reconstructions of the femoral head in each group; (D) Calcein staining images showing mineral apposition in each group (scale bar = 25 μm); (E) Quantitative analysis of vascular volume fraction from micro-CT angiography; (F) Quantification of mineral apposition rate (MAR) in each group. (*P < 0.05, ***P < 0.001, ****P < 0.0001).

Journal: PLOS One

Article Title: MMP-2 associated imbalance of VEGF/Endostatin is linked to suppression of the PI3K/AKT/HIF-1α pathway in steroid-induced osteonecrosis of femoral head

doi: 10.1371/journal.pone.0346880

Figure Lengend Snippet: (A) Representative HE staining images of the femoral head in control, SONFH, and SONFH+Endostatin groups (scale bar = 100 μm); (B) Quantitative analysis of percentage of empty osteocyte from HE staining; (C) Representative micro-CT vascular reconstructions of the femoral head in each group; (D) Calcein staining images showing mineral apposition in each group (scale bar = 25 μm); (E) Quantitative analysis of vascular volume fraction from micro-CT angiography; (F) Quantification of mineral apposition rate (MAR) in each group. (*P < 0.05, ***P < 0.001, ****P < 0.0001).

Article Snippet: Mice in the SONFH+MMP-2 group received subcutaneous injections of recombinant MMP-2 (10 μg/kg; MedChemExpress, NJ, USA) every three days [ , ], while those in the SONFH+Endostatin group were administered daily subcutaneous injections of recombinant Endostatin (2 mg/kg; MedChemExpress, NJ, USA) [ ].

Techniques: Staining, Control, Micro-CT

(A) Relative mRNA levels of Endostatin in the femoral head tissues of each group; (B) Western blotting images showing Endostatin protein expression; (C) Quantification of Endostatin protein levels; (D) Representative immunofluorescence images of Endostatin expression; (E) Quantitative analysis of Endostatin immunofluorescence intensity. (*P < 0.05, **P < 0.01, ***P < 0.001).

Journal: PLOS One

Article Title: MMP-2 associated imbalance of VEGF/Endostatin is linked to suppression of the PI3K/AKT/HIF-1α pathway in steroid-induced osteonecrosis of femoral head

doi: 10.1371/journal.pone.0346880

Figure Lengend Snippet: (A) Relative mRNA levels of Endostatin in the femoral head tissues of each group; (B) Western blotting images showing Endostatin protein expression; (C) Quantification of Endostatin protein levels; (D) Representative immunofluorescence images of Endostatin expression; (E) Quantitative analysis of Endostatin immunofluorescence intensity. (*P < 0.05, **P < 0.01, ***P < 0.001).

Article Snippet: Mice in the SONFH+MMP-2 group received subcutaneous injections of recombinant MMP-2 (10 μg/kg; MedChemExpress, NJ, USA) every three days [ , ], while those in the SONFH+Endostatin group were administered daily subcutaneous injections of recombinant Endostatin (2 mg/kg; MedChemExpress, NJ, USA) [ ].

Techniques: Western Blot, Expressing, Immunofluorescence

Effect of nicorandil (Nic) and aflibercept (Afl) on blood pressure. ( a ) Systolic (SBP), ( b ) diastolic (DBP), and ( c ) mean arterial pressure (MBP). Ctrl: control group, Afl: aflibercept group (10 mg/kg twice a week subcutaneously), Nic: nicorandil group (10 mg/kg/day via drinking water), and Com: combination group (aflibercept [10 mg/kg twice a week] + nicorandil [10 mg/kg/day via drinking water]). n = 6 in each group, *indicates p < 0.05 according to two-way analysis of variance (ANOVA) test.

Journal: Scientific Reports

Article Title: Potential impact of nicorandil on the pharmacodynamics of anti-angiogenic agents

doi: 10.1038/s41598-026-37059-z

Figure Lengend Snippet: Effect of nicorandil (Nic) and aflibercept (Afl) on blood pressure. ( a ) Systolic (SBP), ( b ) diastolic (DBP), and ( c ) mean arterial pressure (MBP). Ctrl: control group, Afl: aflibercept group (10 mg/kg twice a week subcutaneously), Nic: nicorandil group (10 mg/kg/day via drinking water), and Com: combination group (aflibercept [10 mg/kg twice a week] + nicorandil [10 mg/kg/day via drinking water]). n = 6 in each group, *indicates p < 0.05 according to two-way analysis of variance (ANOVA) test.

Article Snippet: The antiangiogenic agent aflibercept (ZALTRAP IV infusion) was purchased from Sanofi K. K. (Tokyo, Japan).

Techniques: Control

( a ) Comparison of tumor volume (mm 3 ) between the four treatment groups. Ctrl: control group, Afl: aflibercept group (10 mg/kg twice a week subcutaneously), Nic: nicorandil group (10 mg/kg/day via drinking water), and Com: combination group (aflibercept [10 mg/kg twice a week] + nicorandil [10 mg/kg/day via drinking water]). n = 4–6 in each group, *indicates p < 0.05 according to two-way analysis of variance (ANOVA) test. ( b ) In vivo imaging analysis of tumor bearing mice. Luminescent images derived from MDA-MB-231-Luc cells subcutaneously transplanted in the back of the nude-mice was taken from the IVIS system. Pictures were taken 35 days after drug treatment initiation.

Journal: Scientific Reports

Article Title: Potential impact of nicorandil on the pharmacodynamics of anti-angiogenic agents

doi: 10.1038/s41598-026-37059-z

Figure Lengend Snippet: ( a ) Comparison of tumor volume (mm 3 ) between the four treatment groups. Ctrl: control group, Afl: aflibercept group (10 mg/kg twice a week subcutaneously), Nic: nicorandil group (10 mg/kg/day via drinking water), and Com: combination group (aflibercept [10 mg/kg twice a week] + nicorandil [10 mg/kg/day via drinking water]). n = 4–6 in each group, *indicates p < 0.05 according to two-way analysis of variance (ANOVA) test. ( b ) In vivo imaging analysis of tumor bearing mice. Luminescent images derived from MDA-MB-231-Luc cells subcutaneously transplanted in the back of the nude-mice was taken from the IVIS system. Pictures were taken 35 days after drug treatment initiation.

Article Snippet: The antiangiogenic agent aflibercept (ZALTRAP IV infusion) was purchased from Sanofi K. K. (Tokyo, Japan).

Techniques: Comparison, Control, In Vivo Imaging, Derivative Assay