ancbe4max Search Results


ancbe4max p2a gfp  (Addgene inc)
94
Addgene inc ancbe4max p2a gfp
Ancbe4max P2a Gfp, supplied by Addgene inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ancbe4max p2a gfp/product/Addgene inc
Average 94 stars, based on 1 article reviews
ancbe4max p2a gfp - by Bioz Stars, 2026-06
94/100 stars
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pcmv ancbe4max  (Addgene inc)
93
Addgene inc pcmv ancbe4max
Pcmv Ancbe4max, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/pcmv ancbe4max/product/Addgene inc
Average 93 stars, based on 1 article reviews
pcmv ancbe4max - by Bioz Stars, 2026-06
93/100 stars
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pef ancbe4max  (Addgene inc)
93
Addgene inc pef ancbe4max
Pef Ancbe4max, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/pef ancbe4max/product/Addgene inc
Average 93 stars, based on 1 article reviews
pef ancbe4max - by Bioz Stars, 2026-06
93/100 stars
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pb xl ancbe4max  (Addgene inc)
90
Addgene inc pb xl ancbe4max
WGS analysis of iPSC clones after long-term cytidine base editor expression reveals increased mutations. a Schematic of the doxycycline-inducible <t>XL-AncBE4max</t> piggyBAC construct inserted into the CL1 line. b Diagrammatic representation of experimental design for clonal expansion and whole-genome sequencing analysis of iPSCs with or without doxycycline-induced 21-day base editor expression. c Mutation numbers in uninduced (ANC-1 and ANC-2) and induced (AN21-1 and AN21-2) iPSC clones. The numbers are total sequence variations, including indels and single nucleotide variations, as compared to the sequence of the parental CL1 iPSCs. d Fractions of each type of mutations in uninduced and induced clones. Source data for c and d are provided in the Source Data file.
Pb Xl Ancbe4max, supplied by Addgene inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/pb xl ancbe4max/product/Addgene inc
Average 90 stars, based on 1 article reviews
pb xl ancbe4max - by Bioz Stars, 2026-06
90/100 stars
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ancbe4max  (Synbio Technologies LLC)
90
Synbio Technologies LLC ancbe4max
WGS analysis of iPSC clones after long-term cytidine base editor expression reveals increased mutations. a Schematic of the doxycycline-inducible <t>XL-AncBE4max</t> piggyBAC construct inserted into the CL1 line. b Diagrammatic representation of experimental design for clonal expansion and whole-genome sequencing analysis of iPSCs with or without doxycycline-induced 21-day base editor expression. c Mutation numbers in uninduced (ANC-1 and ANC-2) and induced (AN21-1 and AN21-2) iPSC clones. The numbers are total sequence variations, including indels and single nucleotide variations, as compared to the sequence of the parental CL1 iPSCs. d Fractions of each type of mutations in uninduced and induced clones. Source data for c and d are provided in the Source Data file.
Ancbe4max, supplied by Synbio Technologies LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ancbe4max/product/Synbio Technologies LLC
Average 90 stars, based on 1 article reviews
ancbe4max - by Bioz Stars, 2026-06
90/100 stars
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Image Search Results


WGS analysis of iPSC clones after long-term cytidine base editor expression reveals increased mutations. a Schematic of the doxycycline-inducible XL-AncBE4max piggyBAC construct inserted into the CL1 line. b Diagrammatic representation of experimental design for clonal expansion and whole-genome sequencing analysis of iPSCs with or without doxycycline-induced 21-day base editor expression. c Mutation numbers in uninduced (ANC-1 and ANC-2) and induced (AN21-1 and AN21-2) iPSC clones. The numbers are total sequence variations, including indels and single nucleotide variations, as compared to the sequence of the parental CL1 iPSCs. d Fractions of each type of mutations in uninduced and induced clones. Source data for c and d are provided in the Source Data file.

Journal: Nature Communications

Article Title: Targeting specificity of APOBEC-based cytosine base editor in human iPSCs determined by whole genome sequencing

doi: 10.1038/s41467-019-13342-8

Figure Lengend Snippet: WGS analysis of iPSC clones after long-term cytidine base editor expression reveals increased mutations. a Schematic of the doxycycline-inducible XL-AncBE4max piggyBAC construct inserted into the CL1 line. b Diagrammatic representation of experimental design for clonal expansion and whole-genome sequencing analysis of iPSCs with or without doxycycline-induced 21-day base editor expression. c Mutation numbers in uninduced (ANC-1 and ANC-2) and induced (AN21-1 and AN21-2) iPSC clones. The numbers are total sequence variations, including indels and single nucleotide variations, as compared to the sequence of the parental CL1 iPSCs. d Fractions of each type of mutations in uninduced and induced clones. Source data for c and d are provided in the Source Data file.

Article Snippet: All plasmids used in this study are available from Addgene: PB-XL-AncBE4max (#136254), gRNA-HEK3-Puro (#136282), pCMV_AncBE4max_P2A_GFP (#112100).

Techniques: Clone Assay, Expressing, Construct, Sequencing, Mutagenesis