ampka Search Results


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Upstate Biotechnology Inc rabbit polyclonal antibodies to phospho-acc
Rabbit Polyclonal Antibodies To Phospho Acc, supplied by Upstate Biotechnology Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ABclonal Biotechnology anti-ampka
Anti Ampka, supplied by ABclonal Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Eton Bioscience adenovirus expressing a dominant negative form of the ampka subunit
Adenovirus Expressing A Dominant Negative Form Of The Ampka Subunit, supplied by Eton Bioscience, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Cyagen Biosciences adenosine 5'-monophosphate (amp)-activated protein kinase (ampka)2 knockout mice
Adenosine 5' Monophosphate (Amp) Activated Protein Kinase (Ampka)2 Knockout Mice, supplied by Cyagen Biosciences, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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RayBiotech inc raybiotech-specific elisa kit
Pentoxifylline stimulated hepatic adenosine-monophosphate-activated protein kinase/mechanistic target of <t>rapamycin</t> <t>(AMPK/mTOR)</t> pathway in doxorubicin-intoxicated rats. Pentoxifylline (PTX; 100 mg/kg) was orally received daily, while doxorubicin (DOX; 18 mg/kg total cumulative dose; 3 mg/kg dose weekly) was received by the intraperitoneal route. The treatments were administered for 6 weeks. Herein, the protein expression of hepatic p-AMPK(Ser487), total AMPK, p-mTOR(Ser2448), and total mTOR was determined by <t>ELISA.</t> In the hepatic tissue of DOX-intoxicated rats, PTX resulted in an elevated p-AMPK(Ser487)/AMPK ratio ( A ) and diminished p-mTOR(Ser2448)/mTOR ratio ( B ). For n = 6, the values were shown as mean ± S.E.M. * p < 0.05, *** p < 0.001, or **** p < 0.0001 vs. control; # p < 0.05, ## p < 0.01 vs. DOX group. PTX, pentoxifylline; DOX, doxorubicin.
Raybiotech Specific Elisa Kit, supplied by RayBiotech inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ABclonal Biotechnology rabbit anti-p-ampka (ser485
Pentoxifylline stimulated hepatic adenosine-monophosphate-activated protein kinase/mechanistic target of <t>rapamycin</t> <t>(AMPK/mTOR)</t> pathway in doxorubicin-intoxicated rats. Pentoxifylline (PTX; 100 mg/kg) was orally received daily, while doxorubicin (DOX; 18 mg/kg total cumulative dose; 3 mg/kg dose weekly) was received by the intraperitoneal route. The treatments were administered for 6 weeks. Herein, the protein expression of hepatic p-AMPK(Ser487), total AMPK, p-mTOR(Ser2448), and total mTOR was determined by <t>ELISA.</t> In the hepatic tissue of DOX-intoxicated rats, PTX resulted in an elevated p-AMPK(Ser487)/AMPK ratio ( A ) and diminished p-mTOR(Ser2448)/mTOR ratio ( B ). For n = 6, the values were shown as mean ± S.E.M. * p < 0.05, *** p < 0.001, or **** p < 0.0001 vs. control; # p < 0.05, ## p < 0.01 vs. DOX group. PTX, pentoxifylline; DOX, doxorubicin.
Rabbit Anti P Ampka (Ser485, supplied by ABclonal Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Genechem sirna targeting ampka
Pentoxifylline stimulated hepatic adenosine-monophosphate-activated protein kinase/mechanistic target of <t>rapamycin</t> <t>(AMPK/mTOR)</t> pathway in doxorubicin-intoxicated rats. Pentoxifylline (PTX; 100 mg/kg) was orally received daily, while doxorubicin (DOX; 18 mg/kg total cumulative dose; 3 mg/kg dose weekly) was received by the intraperitoneal route. The treatments were administered for 6 weeks. Herein, the protein expression of hepatic p-AMPK(Ser487), total AMPK, p-mTOR(Ser2448), and total mTOR was determined by <t>ELISA.</t> In the hepatic tissue of DOX-intoxicated rats, PTX resulted in an elevated p-AMPK(Ser487)/AMPK ratio ( A ) and diminished p-mTOR(Ser2448)/mTOR ratio ( B ). For n = 6, the values were shown as mean ± S.E.M. * p < 0.05, *** p < 0.001, or **** p < 0.0001 vs. control; # p < 0.05, ## p < 0.01 vs. DOX group. PTX, pentoxifylline; DOX, doxorubicin.
Sirna Targeting Ampka, supplied by Genechem, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Zeneca Ltd antisera against ampka
Pentoxifylline stimulated hepatic adenosine-monophosphate-activated protein kinase/mechanistic target of <t>rapamycin</t> <t>(AMPK/mTOR)</t> pathway in doxorubicin-intoxicated rats. Pentoxifylline (PTX; 100 mg/kg) was orally received daily, while doxorubicin (DOX; 18 mg/kg total cumulative dose; 3 mg/kg dose weekly) was received by the intraperitoneal route. The treatments were administered for 6 weeks. Herein, the protein expression of hepatic p-AMPK(Ser487), total AMPK, p-mTOR(Ser2448), and total mTOR was determined by <t>ELISA.</t> In the hepatic tissue of DOX-intoxicated rats, PTX resulted in an elevated p-AMPK(Ser487)/AMPK ratio ( A ) and diminished p-mTOR(Ser2448)/mTOR ratio ( B ). For n = 6, the values were shown as mean ± S.E.M. * p < 0.05, *** p < 0.001, or **** p < 0.0001 vs. control; # p < 0.05, ## p < 0.01 vs. DOX group. PTX, pentoxifylline; DOX, doxorubicin.
Antisera Against Ampka, supplied by Zeneca Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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clea japan inc ampka activator (5-aminoimidazole-4-carboxamide-1b-d-ribofuranoside; aicar)
Pentoxifylline stimulated hepatic adenosine-monophosphate-activated protein kinase/mechanistic target of <t>rapamycin</t> <t>(AMPK/mTOR)</t> pathway in doxorubicin-intoxicated rats. Pentoxifylline (PTX; 100 mg/kg) was orally received daily, while doxorubicin (DOX; 18 mg/kg total cumulative dose; 3 mg/kg dose weekly) was received by the intraperitoneal route. The treatments were administered for 6 weeks. Herein, the protein expression of hepatic p-AMPK(Ser487), total AMPK, p-mTOR(Ser2448), and total mTOR was determined by <t>ELISA.</t> In the hepatic tissue of DOX-intoxicated rats, PTX resulted in an elevated p-AMPK(Ser487)/AMPK ratio ( A ) and diminished p-mTOR(Ser2448)/mTOR ratio ( B ). For n = 6, the values were shown as mean ± S.E.M. * p < 0.05, *** p < 0.001, or **** p < 0.0001 vs. control; # p < 0.05, ## p < 0.01 vs. DOX group. PTX, pentoxifylline; DOX, doxorubicin.
Ampka Activator (5 Aminoimidazole 4 Carboxamide 1b D Ribofuranoside; Aicar), supplied by clea japan inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Shanghai GenePharma ampka sirna
Pentoxifylline stimulated hepatic adenosine-monophosphate-activated protein kinase/mechanistic target of <t>rapamycin</t> <t>(AMPK/mTOR)</t> pathway in doxorubicin-intoxicated rats. Pentoxifylline (PTX; 100 mg/kg) was orally received daily, while doxorubicin (DOX; 18 mg/kg total cumulative dose; 3 mg/kg dose weekly) was received by the intraperitoneal route. The treatments were administered for 6 weeks. Herein, the protein expression of hepatic p-AMPK(Ser487), total AMPK, p-mTOR(Ser2448), and total mTOR was determined by <t>ELISA.</t> In the hepatic tissue of DOX-intoxicated rats, PTX resulted in an elevated p-AMPK(Ser487)/AMPK ratio ( A ) and diminished p-mTOR(Ser2448)/mTOR ratio ( B ). For n = 6, the values were shown as mean ± S.E.M. * p < 0.05, *** p < 0.001, or **** p < 0.0001 vs. control; # p < 0.05, ## p < 0.01 vs. DOX group. PTX, pentoxifylline; DOX, doxorubicin.
Ampka Sirna, supplied by Shanghai GenePharma, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Beyotime rabbit monoclonal anti-human ampka
Pentoxifylline stimulated hepatic adenosine-monophosphate-activated protein kinase/mechanistic target of <t>rapamycin</t> <t>(AMPK/mTOR)</t> pathway in doxorubicin-intoxicated rats. Pentoxifylline (PTX; 100 mg/kg) was orally received daily, while doxorubicin (DOX; 18 mg/kg total cumulative dose; 3 mg/kg dose weekly) was received by the intraperitoneal route. The treatments were administered for 6 weeks. Herein, the protein expression of hepatic p-AMPK(Ser487), total AMPK, p-mTOR(Ser2448), and total mTOR was determined by <t>ELISA.</t> In the hepatic tissue of DOX-intoxicated rats, PTX resulted in an elevated p-AMPK(Ser487)/AMPK ratio ( A ) and diminished p-mTOR(Ser2448)/mTOR ratio ( B ). For n = 6, the values were shown as mean ± S.E.M. * p < 0.05, *** p < 0.001, or **** p < 0.0001 vs. control; # p < 0.05, ## p < 0.01 vs. DOX group. PTX, pentoxifylline; DOX, doxorubicin.
Rabbit Monoclonal Anti Human Ampka, supplied by Beyotime, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ZenBio antibody to phospho-ampk (thr172)
Pentoxifylline stimulated hepatic adenosine-monophosphate-activated protein kinase/mechanistic target of <t>rapamycin</t> <t>(AMPK/mTOR)</t> pathway in doxorubicin-intoxicated rats. Pentoxifylline (PTX; 100 mg/kg) was orally received daily, while doxorubicin (DOX; 18 mg/kg total cumulative dose; 3 mg/kg dose weekly) was received by the intraperitoneal route. The treatments were administered for 6 weeks. Herein, the protein expression of hepatic p-AMPK(Ser487), total AMPK, p-mTOR(Ser2448), and total mTOR was determined by <t>ELISA.</t> In the hepatic tissue of DOX-intoxicated rats, PTX resulted in an elevated p-AMPK(Ser487)/AMPK ratio ( A ) and diminished p-mTOR(Ser2448)/mTOR ratio ( B ). For n = 6, the values were shown as mean ± S.E.M. * p < 0.05, *** p < 0.001, or **** p < 0.0001 vs. control; # p < 0.05, ## p < 0.01 vs. DOX group. PTX, pentoxifylline; DOX, doxorubicin.
Antibody To Phospho Ampk (Thr172), supplied by ZenBio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Pentoxifylline stimulated hepatic adenosine-monophosphate-activated protein kinase/mechanistic target of rapamycin (AMPK/mTOR) pathway in doxorubicin-intoxicated rats. Pentoxifylline (PTX; 100 mg/kg) was orally received daily, while doxorubicin (DOX; 18 mg/kg total cumulative dose; 3 mg/kg dose weekly) was received by the intraperitoneal route. The treatments were administered for 6 weeks. Herein, the protein expression of hepatic p-AMPK(Ser487), total AMPK, p-mTOR(Ser2448), and total mTOR was determined by ELISA. In the hepatic tissue of DOX-intoxicated rats, PTX resulted in an elevated p-AMPK(Ser487)/AMPK ratio ( A ) and diminished p-mTOR(Ser2448)/mTOR ratio ( B ). For n = 6, the values were shown as mean ± S.E.M. * p < 0.05, *** p < 0.001, or **** p < 0.0001 vs. control; # p < 0.05, ## p < 0.01 vs. DOX group. PTX, pentoxifylline; DOX, doxorubicin.

Journal: Pharmaceuticals

Article Title: Activation of AMPK/mTOR-Driven Autophagy and Suppression of the HMGB1/TLR4 Pathway with Pentoxifylline Attenuates Doxorubicin-Induced Hepatic Injury in Rats

doi: 10.3390/ph17060681

Figure Lengend Snippet: Pentoxifylline stimulated hepatic adenosine-monophosphate-activated protein kinase/mechanistic target of rapamycin (AMPK/mTOR) pathway in doxorubicin-intoxicated rats. Pentoxifylline (PTX; 100 mg/kg) was orally received daily, while doxorubicin (DOX; 18 mg/kg total cumulative dose; 3 mg/kg dose weekly) was received by the intraperitoneal route. The treatments were administered for 6 weeks. Herein, the protein expression of hepatic p-AMPK(Ser487), total AMPK, p-mTOR(Ser2448), and total mTOR was determined by ELISA. In the hepatic tissue of DOX-intoxicated rats, PTX resulted in an elevated p-AMPK(Ser487)/AMPK ratio ( A ) and diminished p-mTOR(Ser2448)/mTOR ratio ( B ). For n = 6, the values were shown as mean ± S.E.M. * p < 0.05, *** p < 0.001, or **** p < 0.0001 vs. control; # p < 0.05, ## p < 0.01 vs. DOX group. PTX, pentoxifylline; DOX, doxorubicin.

Article Snippet: The hepatic content of p-AMPK and total AMPK was measured using a RayBiotech-specific ELISA kit (Norcross, GA, USA; Cat. No. PEL-AMPKA-S487-T), as recommended by the vendor.

Techniques: Expressing, Enzyme-linked Immunosorbent Assay