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Image Search Results
Journal: Aging (Albany NY)
Article Title: NFAT5 directs hyperosmotic stress-induced fibrin deposition and macrophage infiltration via PAI-1 in endothelium
doi: 10.18632/aging.202330
Figure Lengend Snippet: High-salt induces the dysfunction of PAI-1-dependent fibrinolysis in ECs via NFAT5. ( A – D ) mRNA and protein expression of fibrinolysis genes (PLAT, PLAU and PLG) in HUVECs that treated by Adenovirus-null (Ad-null) or Adenovirus-NFAT5 (Ad-NFAT5). ( E – H ) mRNA and protein expression of fibrinolysis genes (PLAT, PLAU and PLG) in HUVECs that transfected with Ctr siRNA or NFAT5 siRNA under high-salt condition. All data were presented as mean ± SEM, N≥3. *p < 0.05 versus control group.
Article Snippet: After electrotransferring onto PVDF membranes, the blots were treated with different primary antibodies [NFAT5 (Abcam, Cambridge, MA), PAI-1 (Abcam, Cambridge, MA),
Techniques: Expressing, Transfection, Control