90
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Alomone Labs
af 353 Af 353, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/af-353/AF-353/10__2147_slash_jir__s313348-57-33-62 Average 90 stars, based on 1 article reviews
af 353 - by Bioz Stars,
2026-09
90/100 stars
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90
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MedChemExpress
2 4 diamine 2 4 Diamine, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/af-353/AF-353/pm34622458-41-3-20 Average 90 stars, based on 1 article reviews
2 4 diamine - by Bioz Stars,
2026-09
90/100 stars
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93
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Selleck Chemicals
af Af, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/af-353/AF-353/pm38745397-238-0-5 Average 93 stars, based on 1 article reviews
af - by Bioz Stars,
2026-09
93/100 stars
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90
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Afferent Pharmaceuticals
af-353 Af 353, supplied by Afferent Pharmaceuticals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/af-353/af+353/pmc04358674-51-4-5 Average 90 stars, based on 1 article reviews
af-353 - by Bioz Stars,
2026-09
90/100 stars
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90
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Johns Hopkins HealthCare
af-353 Af 353, supplied by Johns Hopkins HealthCare, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/af-353/af+353/pmc03265711-168-73-109 Average 90 stars, based on 1 article reviews
af-353 - by Bioz Stars,
2026-09
90/100 stars
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N/A
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InformationAF-353 AF-353 (Ro-4) is a potent, selective and orally bioavailable antagonist of P2X3 receptor and P2X2/3 receptor with pIC50 of 8.06, 8.05 and 7.41 for human P2X3, rat P2X3 and human P2X2/3, respectively.TargetshP2X3 (Cell-free assay);
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N/A
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Antagonist of P2X3/P2X2/3 purinoreceptors. Antagonist of P2X3/P2X2/3 purinoreceptors.
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N/A
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AF-353 is a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist. It is a highly potent inhibitor of α,β-meATP-evoked intracellular calcium flux in cell lines expressing recombinant rat and human P2X3 and human P2X2/3 channels.
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