HY-N6602R Search Results


α solanine  (MedChemExpress)
94
MedChemExpress α solanine
Fig. 1. Effects <t>of</t> <t>α-solanine</t> on cell viability of tumor necrosis factor alpha (TNF-α)-overexpressed human umbilical vein endothelial cells (HUVECs). A. Cell viability of HUVECs under the treatment of different concentrations of α-solanine. Data were analyzed with Kruskal–Wallis H (K–W) test followed by Dunn–Bonferroni (D–B) test (K–W test: H = 44.802, degrees of freedom (df) = 5, p < 0.001; * p < 0.05 compared to 0 μg/mL, n = 5); B. TNF-α relative mRNA expression level and TNF-α relative protein expression level in HUVECs after the transfection of the pcDNA3.1(+) plasmid vector or the TNF-α overexpression vector. Data were analyzed using K–W test followed by D–B test (K–W test: mRNA, H = 23.143, df = 2, p < 0.001; protein, H = 11.439, df = 2, p = 0.003; * p < 0.05 compared to vector; # p < 0.05 compared to TNF-α, n = 3); C. Effects of α-solanine treatment on the cell viability of HUVECs transfected with TNF-α vector. Data were analyzed with K–W test followed by D–B test (K–W test: H = 46.700, df = 5, p < 0.001; * p < 0.05 compared to control; # p < 0.05 compared to vector; n = 5)Fig. 1. Effects of α-solanine on cell viability of tumor necrosis factor alpha (TNF-α)-overexpressed human umbilical vein endothelial cells (HUVECs). A. Cell viability of HUVECs under the treatment of different concentrations of α-solanine. Data were analyzed with Kruskal–Wallis H (K–W) test followed by Dunn–Bonferroni (D–B) test (K–W test: H = 44.802, degrees of freedom (df) = 5, p < 0.001; * p < 0.05 compared to 0 μg/mL, n = 5); B. TNF-α relative mRNA expression level and TNF-α relative protein expression level in HUVECs after the transfection of the pcDNA3.1(+) plasmid vector or the TNF-α overexpression vector. Data were analyzed using K–W test followed by D–B test (K–W test: mRNA, H = 23.143, df = 2, p < 0.001; protein, H = 11.439, df = 2, p = 0.003; * p < 0.05 compared to vector; # p < 0.05 compared to TNF-α, n = 3); C. Effects of α-solanine treatment on the cell viability of HUVECs transfected with TNF-α vector. Data were analyzed with K–W test followed by D–B test (K–W test: H = 46.700, df = 5, p < 0.001; * p < 0.05 compared to control; # p < 0.05 compared to vector; n = 5)
α Solanine, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/α solanine/product/MedChemExpress
Average 94 stars, based on 1 article reviews
α solanine - by Bioz Stars, 2026-02
94/100 stars
  Buy from Supplier

Image Search Results


Fig. 1. Effects of α-solanine on cell viability of tumor necrosis factor alpha (TNF-α)-overexpressed human umbilical vein endothelial cells (HUVECs). A. Cell viability of HUVECs under the treatment of different concentrations of α-solanine. Data were analyzed with Kruskal–Wallis H (K–W) test followed by Dunn–Bonferroni (D–B) test (K–W test: H = 44.802, degrees of freedom (df) = 5, p < 0.001; * p < 0.05 compared to 0 μg/mL, n = 5); B. TNF-α relative mRNA expression level and TNF-α relative protein expression level in HUVECs after the transfection of the pcDNA3.1(+) plasmid vector or the TNF-α overexpression vector. Data were analyzed using K–W test followed by D–B test (K–W test: mRNA, H = 23.143, df = 2, p < 0.001; protein, H = 11.439, df = 2, p = 0.003; * p < 0.05 compared to vector; # p < 0.05 compared to TNF-α, n = 3); C. Effects of α-solanine treatment on the cell viability of HUVECs transfected with TNF-α vector. Data were analyzed with K–W test followed by D–B test (K–W test: H = 46.700, df = 5, p < 0.001; * p < 0.05 compared to control; # p < 0.05 compared to vector; n = 5)Fig. 1. Effects of α-solanine on cell viability of tumor necrosis factor alpha (TNF-α)-overexpressed human umbilical vein endothelial cells (HUVECs). A. Cell viability of HUVECs under the treatment of different concentrations of α-solanine. Data were analyzed with Kruskal–Wallis H (K–W) test followed by Dunn–Bonferroni (D–B) test (K–W test: H = 44.802, degrees of freedom (df) = 5, p < 0.001; * p < 0.05 compared to 0 μg/mL, n = 5); B. TNF-α relative mRNA expression level and TNF-α relative protein expression level in HUVECs after the transfection of the pcDNA3.1(+) plasmid vector or the TNF-α overexpression vector. Data were analyzed using K–W test followed by D–B test (K–W test: mRNA, H = 23.143, df = 2, p < 0.001; protein, H = 11.439, df = 2, p = 0.003; * p < 0.05 compared to vector; # p < 0.05 compared to TNF-α, n = 3); C. Effects of α-solanine treatment on the cell viability of HUVECs transfected with TNF-α vector. Data were analyzed with K–W test followed by D–B test (K–W test: H = 46.700, df = 5, p < 0.001; * p < 0.05 compared to control; # p < 0.05 compared to vector; n = 5)

Journal: Advances in clinical and experimental medicine : official organ Wroclaw Medical University

Article Title: Alpha-solanine inhibits endothelial inflammation via nuclear factor kappa B signaling pathway.

doi: 10.17219/acem/158781

Figure Lengend Snippet: Fig. 1. Effects of α-solanine on cell viability of tumor necrosis factor alpha (TNF-α)-overexpressed human umbilical vein endothelial cells (HUVECs). A. Cell viability of HUVECs under the treatment of different concentrations of α-solanine. Data were analyzed with Kruskal–Wallis H (K–W) test followed by Dunn–Bonferroni (D–B) test (K–W test: H = 44.802, degrees of freedom (df) = 5, p < 0.001; * p < 0.05 compared to 0 μg/mL, n = 5); B. TNF-α relative mRNA expression level and TNF-α relative protein expression level in HUVECs after the transfection of the pcDNA3.1(+) plasmid vector or the TNF-α overexpression vector. Data were analyzed using K–W test followed by D–B test (K–W test: mRNA, H = 23.143, df = 2, p < 0.001; protein, H = 11.439, df = 2, p = 0.003; * p < 0.05 compared to vector; # p < 0.05 compared to TNF-α, n = 3); C. Effects of α-solanine treatment on the cell viability of HUVECs transfected with TNF-α vector. Data were analyzed with K–W test followed by D–B test (K–W test: H = 46.700, df = 5, p < 0.001; * p < 0.05 compared to control; # p < 0.05 compared to vector; n = 5)Fig. 1. Effects of α-solanine on cell viability of tumor necrosis factor alpha (TNF-α)-overexpressed human umbilical vein endothelial cells (HUVECs). A. Cell viability of HUVECs under the treatment of different concentrations of α-solanine. Data were analyzed with Kruskal–Wallis H (K–W) test followed by Dunn–Bonferroni (D–B) test (K–W test: H = 44.802, degrees of freedom (df) = 5, p < 0.001; * p < 0.05 compared to 0 μg/mL, n = 5); B. TNF-α relative mRNA expression level and TNF-α relative protein expression level in HUVECs after the transfection of the pcDNA3.1(+) plasmid vector or the TNF-α overexpression vector. Data were analyzed using K–W test followed by D–B test (K–W test: mRNA, H = 23.143, df = 2, p < 0.001; protein, H = 11.439, df = 2, p = 0.003; * p < 0.05 compared to vector; # p < 0.05 compared to TNF-α, n = 3); C. Effects of α-solanine treatment on the cell viability of HUVECs transfected with TNF-α vector. Data were analyzed with K–W test followed by D–B test (K–W test: H = 46.700, df = 5, p < 0.001; * p < 0.05 compared to control; # p < 0.05 compared to vector; n = 5)

Article Snippet: The α-solanine (20562-02-1) was purchased from Shanghai Yuanye Bio-Technology Co., Ltd. (Shanghai, China), and SN50 (HY-P0151) from MedChemExpress (Monmouth Junction, USA).

Techniques: Expressing, Transfection, Plasmid Preparation, Over Expression, Control

Fig. 2. Effects of α-solanine on tumor necrosis factor alpha (TNF-α) and interleukin 6 (IL-6) protein levels in TNF-α- overexpressed cells. Data were analyzed with Kruskal–Wallis H (K–W) test followed by Dunn–Bonferroni test (K–W test: TNF-α, H = 42.863, degrees of freedom (df) = 5, p < 0.001; IL-6, H = 46.571, df = 5, p < 0.001; * p < 0.05 compared to control; # p < 0.05 compared to vector; @ p < 0.05 compared to TNF-α; n = 3)Fig. 2. Effects of α-solanine on tumor necrosis factor alpha (TNF-α) and interleukin 6 (IL-6) protein levels in TNF-α-overexpressed cells. Data were analyzed with Kruskal–Wallis H (K–W) test followed by Dunn–Bonferroni test (K–W test: TNF-α, H = 42.863, degrees of freedom (df) = 5, p < 0.001; IL-6, H = 46.571, df = 5, p < 0.001; * p < 0.05 compared to control; # p < 0.05 compared to vector; @ p < 0.05 compared to TNF-α; n = 3)

Journal: Advances in clinical and experimental medicine : official organ Wroclaw Medical University

Article Title: Alpha-solanine inhibits endothelial inflammation via nuclear factor kappa B signaling pathway.

doi: 10.17219/acem/158781

Figure Lengend Snippet: Fig. 2. Effects of α-solanine on tumor necrosis factor alpha (TNF-α) and interleukin 6 (IL-6) protein levels in TNF-α- overexpressed cells. Data were analyzed with Kruskal–Wallis H (K–W) test followed by Dunn–Bonferroni test (K–W test: TNF-α, H = 42.863, degrees of freedom (df) = 5, p < 0.001; IL-6, H = 46.571, df = 5, p < 0.001; * p < 0.05 compared to control; # p < 0.05 compared to vector; @ p < 0.05 compared to TNF-α; n = 3)Fig. 2. Effects of α-solanine on tumor necrosis factor alpha (TNF-α) and interleukin 6 (IL-6) protein levels in TNF-α-overexpressed cells. Data were analyzed with Kruskal–Wallis H (K–W) test followed by Dunn–Bonferroni test (K–W test: TNF-α, H = 42.863, degrees of freedom (df) = 5, p < 0.001; IL-6, H = 46.571, df = 5, p < 0.001; * p < 0.05 compared to control; # p < 0.05 compared to vector; @ p < 0.05 compared to TNF-α; n = 3)

Article Snippet: The α-solanine (20562-02-1) was purchased from Shanghai Yuanye Bio-Technology Co., Ltd. (Shanghai, China), and SN50 (HY-P0151) from MedChemExpress (Monmouth Junction, USA).

Techniques: Control, Plasmid Preparation

Fig. 3. Effect of α-solanine on phospho-inhibitor of NF-κBα (p-IκBα), phospho-P65 (p-P65) and IκB kinase (IKK) α/β relative protein expression levels in tumor necrosis factor alpha (TNF-α)-overexpressed cells. Data were analyzed with Kruskal–Wallis H (K–W) test followed by Dunn–Bonferroni test (K–W test: p-IκBα, H = 29.841, degrees of freedom (df) = 5, p < 0.001; p-P65, H = 28.052, df = 5, p < 0.001; IKKα/β, H = 25.441, df = 5, p < 0.001; * p < 0.05 compared to control; # p < 0.05 compared to vector; @ p < 0.05 compared to TNF-α; n = 3)Fig. 3. Effect of α-solanine on phospho-inhibitor of NF-κBα (p-IκBα), phospho-P65 (p-P65) and IκB kinase (IKK) α/β relative protein expression levels in tumor necrosis factor alpha (TNF-α)-overexpressed cells. Data were analyzed with Kruskal–Wallis H (K–W) test followed by Dunn–Bonferroni test (K–W test: p-IκBα, H = 29.841, degrees of freedom (df) = 5, p < 0.001; p-P65, H = 28.052, df = 5, p < 0.001; IKKα/β, H = 25.441, df = 5, p < 0.001; * p < 0.05 compared to control; # p < 0.05 compared to vector; @ p < 0.05 compared to TNF-α; n = 3)

Journal: Advances in clinical and experimental medicine : official organ Wroclaw Medical University

Article Title: Alpha-solanine inhibits endothelial inflammation via nuclear factor kappa B signaling pathway.

doi: 10.17219/acem/158781

Figure Lengend Snippet: Fig. 3. Effect of α-solanine on phospho-inhibitor of NF-κBα (p-IκBα), phospho-P65 (p-P65) and IκB kinase (IKK) α/β relative protein expression levels in tumor necrosis factor alpha (TNF-α)-overexpressed cells. Data were analyzed with Kruskal–Wallis H (K–W) test followed by Dunn–Bonferroni test (K–W test: p-IκBα, H = 29.841, degrees of freedom (df) = 5, p < 0.001; p-P65, H = 28.052, df = 5, p < 0.001; IKKα/β, H = 25.441, df = 5, p < 0.001; * p < 0.05 compared to control; # p < 0.05 compared to vector; @ p < 0.05 compared to TNF-α; n = 3)Fig. 3. Effect of α-solanine on phospho-inhibitor of NF-κBα (p-IκBα), phospho-P65 (p-P65) and IκB kinase (IKK) α/β relative protein expression levels in tumor necrosis factor alpha (TNF-α)-overexpressed cells. Data were analyzed with Kruskal–Wallis H (K–W) test followed by Dunn–Bonferroni test (K–W test: p-IκBα, H = 29.841, degrees of freedom (df) = 5, p < 0.001; p-P65, H = 28.052, df = 5, p < 0.001; IKKα/β, H = 25.441, df = 5, p < 0.001; * p < 0.05 compared to control; # p < 0.05 compared to vector; @ p < 0.05 compared to TNF-α; n = 3)

Article Snippet: The α-solanine (20562-02-1) was purchased from Shanghai Yuanye Bio-Technology Co., Ltd. (Shanghai, China), and SN50 (HY-P0151) from MedChemExpress (Monmouth Junction, USA).

Techniques: Expressing, Control, Plasmid Preparation