HY-N0104R Search Results


94
MedChemExpress curcumol
Inhibition of <t>Curcumol</t> on drug-resistant cells and synergistic effect on CDDP. (A) The chemical formula and chemical construction of Curcumol. (B) The IC50 index of AGS, MKN45, AGS/DDP, and MKN45/DDP. (C) Curcumol interfered with AGS/DDP and MKN45/DDP for 24 and 48 hours. (D) CDDP <t>and</t> <t>CUR</t> + CDDP act on AGS/DDP and MKN45/DDP, (E) and (F) Synergies 3.0 software calculator simulates the synergies between CUR and CDDP. ** P < .01; N.S. P > .05 NC versus CDDP or CUR + CDDP group (X ± SE, cell experiments were repeated at least three times). One-way ANOVA with Dunnett’s post hoc test.
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Inhibition of Curcumol on drug-resistant cells and synergistic effect on CDDP. (A) The chemical formula and chemical construction of Curcumol. (B) The IC50 index of AGS, MKN45, AGS/DDP, and MKN45/DDP. (C) Curcumol interfered with AGS/DDP and MKN45/DDP for 24 and 48 hours. (D) CDDP and CUR + CDDP act on AGS/DDP and MKN45/DDP, (E) and (F) Synergies 3.0 software calculator simulates the synergies between CUR and CDDP. ** P < .01; N.S. P > .05 NC versus CDDP or CUR + CDDP group (X ± SE, cell experiments were repeated at least three times). One-way ANOVA with Dunnett’s post hoc test.

Journal: Integrative Cancer Therapies

Article Title: Curcumol Enhances the Sensitivity of Gastric Cancer to Cisplatin Resistance by Inducing Ferroptosis Through the P62/KEAP1/NRF2 Pathway

doi: 10.1177/15347354241294043

Figure Lengend Snippet: Inhibition of Curcumol on drug-resistant cells and synergistic effect on CDDP. (A) The chemical formula and chemical construction of Curcumol. (B) The IC50 index of AGS, MKN45, AGS/DDP, and MKN45/DDP. (C) Curcumol interfered with AGS/DDP and MKN45/DDP for 24 and 48 hours. (D) CDDP and CUR + CDDP act on AGS/DDP and MKN45/DDP, (E) and (F) Synergies 3.0 software calculator simulates the synergies between CUR and CDDP. ** P < .01; N.S. P > .05 NC versus CDDP or CUR + CDDP group (X ± SE, cell experiments were repeated at least three times). One-way ANOVA with Dunnett’s post hoc test.

Article Snippet: Curcumol (CUR, Cat#HY-N0104) and CDDP (Cat#HY-17394) were purchased from MedChemExpress (Monmouth Junction, NJ, USA).

Techniques: Inhibition, Software

Curcumol or CDDP alone or in combination induce ferroptosis. (A) Curcumol or CDDP alone or in combination induce ROS. (B) Curcumol or CDDP alone or in combination intervened in MDA indicator trends. (C) Curcumol or CDDP alone or in combination intervened in Fe indicator trends. (D) Curcumol or CDDP alone or in combination intervened in GSH/GSSG ratio. (E) Curcumol or CDDP alone or in combination intervened in C11. * P < .05 ** P < .01 N.S. P > .05 NC versus CUR or CDDP or CUR + CDDP group; # P < .05 CUR or CDDP versus CUR + CDDP (X ± SE, cell experiments were repeated at least three times). One-way ANOVA with Dunnett’s post hoc test.

Journal: Integrative Cancer Therapies

Article Title: Curcumol Enhances the Sensitivity of Gastric Cancer to Cisplatin Resistance by Inducing Ferroptosis Through the P62/KEAP1/NRF2 Pathway

doi: 10.1177/15347354241294043

Figure Lengend Snippet: Curcumol or CDDP alone or in combination induce ferroptosis. (A) Curcumol or CDDP alone or in combination induce ROS. (B) Curcumol or CDDP alone or in combination intervened in MDA indicator trends. (C) Curcumol or CDDP alone or in combination intervened in Fe indicator trends. (D) Curcumol or CDDP alone or in combination intervened in GSH/GSSG ratio. (E) Curcumol or CDDP alone or in combination intervened in C11. * P < .05 ** P < .01 N.S. P > .05 NC versus CUR or CDDP or CUR + CDDP group; # P < .05 CUR or CDDP versus CUR + CDDP (X ± SE, cell experiments were repeated at least three times). One-way ANOVA with Dunnett’s post hoc test.

Article Snippet: Curcumol (CUR, Cat#HY-N0104) and CDDP (Cat#HY-17394) were purchased from MedChemExpress (Monmouth Junction, NJ, USA).

Techniques: