HY-169312 Search Results


smifh2  (MedChemExpress)
94
MedChemExpress smifh2
(A) Plot showing the effect of the knockout of major actin regulators on FPR1 surface levels in the basal (y-axis) and post-stimulation screens (x-axis). Effect of <t>SMIFH2</t> on FPR1 internalization (B) in dHL-60s (20 μM, 50 μM, and 100 μM) and (C) in primary neutrophils (50 μM). Cells are untreated or pre-treated with SMIFH2 for 20 mins. (n=6 for dHL-60s, n=4 for primary neutrophils).
Smifh2, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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(A) Plot showing the effect of the knockout of major actin regulators on FPR1 surface levels in the basal (y-axis) and post-stimulation screens (x-axis). Effect of SMIFH2 on FPR1 internalization (B) in dHL-60s (20 μM, 50 μM, and 100 μM) and (C) in primary neutrophils (50 μM). Cells are untreated or pre-treated with SMIFH2 for 20 mins. (n=6 for dHL-60s, n=4 for primary neutrophils).

Journal: bioRxiv

Article Title: Parallel CRISPR screens reveal pathways controlling the cell surface levels of the attractant receptor FPR1

doi: 10.1101/2025.04.21.649864

Figure Lengend Snippet: (A) Plot showing the effect of the knockout of major actin regulators on FPR1 surface levels in the basal (y-axis) and post-stimulation screens (x-axis). Effect of SMIFH2 on FPR1 internalization (B) in dHL-60s (20 μM, 50 μM, and 100 μM) and (C) in primary neutrophils (50 μM). Cells are untreated or pre-treated with SMIFH2 for 20 mins. (n=6 for dHL-60s, n=4 for primary neutrophils).

Article Snippet: Cells were pre-treated with CMPD 101 (Tocris Biosciences, catalog # 5642), NAV-2729 (Sigma-Aldrich Co., SML2238), or SMIFH2 (MedChemExpress, catalog # HY-16931) at 37°C for 30 min where indicated.

Techniques: Knock-Out

Fold change in surface FPR1 from the control is calculated for different concentrations of SMIFH2 treatment.

Journal: bioRxiv

Article Title: Parallel CRISPR screens reveal pathways controlling the cell surface levels of the attractant receptor FPR1

doi: 10.1101/2025.04.21.649864

Figure Lengend Snippet: Fold change in surface FPR1 from the control is calculated for different concentrations of SMIFH2 treatment.

Article Snippet: Cells were pre-treated with CMPD 101 (Tocris Biosciences, catalog # 5642), NAV-2729 (Sigma-Aldrich Co., SML2238), or SMIFH2 (MedChemExpress, catalog # HY-16931) at 37°C for 30 min where indicated.

Techniques: Control