HY-162737 Search Results


opb  (MedChemExpress)
92
MedChemExpress opb
Opb, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/opb/product/MedChemExpress
Average 92 stars, based on 1 article reviews
opb - by Bioz Stars, 2026-02
92/100 stars
  Buy from Supplier
nanotube inhibitors  (MedChemExpress)
93
MedChemExpress nanotube inhibitors
Hybrids enhance the immunosuppressive function of iDCs and their underlying mechanisms. Flow cytometry sorting and detection of proliferation(A) and PDL-1 levels in total iDCs(B) and the iDCs with obtaining hybrid membrane components(I) after co-culture with hybrids. Live-cell imaging observations revealed that hybrids influence iDCs through cell migration(C), <t>nanotube</t> interactions(D and G), efferocytosis(E), label tracking(F), and label pulling(H). The impact of CK636(J), Dynasore(K) and L778123(L) on the proportion of iDCs cells with hybrid membrane components (DiD + GFP + ) and PDL-1 levels. Data are represented as means±SD (n=3). **P<0.01, ***P<0.001 vs DC 24h in A(two-tailed t-test); ***P<0.001 vs DC and ### P<0.001 vs Hybrid+DC in B(One-way ANOVA Tukey’s multiple comparison); ***P<0.001 vs DC in I(two-tailed t-test); *P<0.05, **P<0.01 vs -IFN-γ/IL-1β and # P<0.05, ## P<0.01, ### P<0.001 vs <t>-CK636/-Dy/-L77</t> in J-L(two-tailed t-test).
Nanotube Inhibitors, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/nanotube inhibitors/product/MedChemExpress
Average 93 stars, based on 1 article reviews
nanotube inhibitors - by Bioz Stars, 2026-02
93/100 stars
  Buy from Supplier
s7609 l778123 medchemexpress  (MedChemExpress)
92
MedChemExpress s7609 l778123 medchemexpress
Hybrids enhance the immunosuppressive function of iDCs and their underlying mechanisms. Flow cytometry sorting and detection of proliferation(A) and PDL-1 levels in total iDCs(B) and the iDCs with obtaining hybrid membrane components(I) after co-culture with hybrids. Live-cell imaging observations revealed that hybrids influence iDCs through cell migration(C), <t>nanotube</t> interactions(D and G), efferocytosis(E), label tracking(F), and label pulling(H). The impact of CK636(J), Dynasore(K) and L778123(L) on the proportion of iDCs cells with hybrid membrane components (DiD + GFP + ) and PDL-1 levels. Data are represented as means±SD (n=3). **P<0.01, ***P<0.001 vs DC 24h in A(two-tailed t-test); ***P<0.001 vs DC and ### P<0.001 vs Hybrid+DC in B(One-way ANOVA Tukey’s multiple comparison); ***P<0.001 vs DC in I(two-tailed t-test); *P<0.05, **P<0.01 vs -IFN-γ/IL-1β and # P<0.05, ## P<0.01, ### P<0.001 vs <t>-CK636/-Dy/-L77</t> in J-L(two-tailed t-test).
S7609 L778123 Medchemexpress, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/s7609 l778123 medchemexpress/product/MedChemExpress
Average 92 stars, based on 1 article reviews
s7609 l778123 medchemexpress - by Bioz Stars, 2026-02
92/100 stars
  Buy from Supplier

Image Search Results


Hybrids enhance the immunosuppressive function of iDCs and their underlying mechanisms. Flow cytometry sorting and detection of proliferation(A) and PDL-1 levels in total iDCs(B) and the iDCs with obtaining hybrid membrane components(I) after co-culture with hybrids. Live-cell imaging observations revealed that hybrids influence iDCs through cell migration(C), nanotube interactions(D and G), efferocytosis(E), label tracking(F), and label pulling(H). The impact of CK636(J), Dynasore(K) and L778123(L) on the proportion of iDCs cells with hybrid membrane components (DiD + GFP + ) and PDL-1 levels. Data are represented as means±SD (n=3). **P<0.01, ***P<0.001 vs DC 24h in A(two-tailed t-test); ***P<0.001 vs DC and ### P<0.001 vs Hybrid+DC in B(One-way ANOVA Tukey’s multiple comparison); ***P<0.001 vs DC in I(two-tailed t-test); *P<0.05, **P<0.01 vs -IFN-γ/IL-1β and # P<0.05, ## P<0.01, ### P<0.001 vs -CK636/-Dy/-L77 in J-L(two-tailed t-test).

Journal: bioRxiv

Article Title: Construction, Phenotypic Characterization, and Immunomodulatory Function Study of BMSC-Macrophage Hybrid in vitro

doi: 10.1101/2025.07.25.666751

Figure Lengend Snippet: Hybrids enhance the immunosuppressive function of iDCs and their underlying mechanisms. Flow cytometry sorting and detection of proliferation(A) and PDL-1 levels in total iDCs(B) and the iDCs with obtaining hybrid membrane components(I) after co-culture with hybrids. Live-cell imaging observations revealed that hybrids influence iDCs through cell migration(C), nanotube interactions(D and G), efferocytosis(E), label tracking(F), and label pulling(H). The impact of CK636(J), Dynasore(K) and L778123(L) on the proportion of iDCs cells with hybrid membrane components (DiD + GFP + ) and PDL-1 levels. Data are represented as means±SD (n=3). **P<0.01, ***P<0.001 vs DC 24h in A(two-tailed t-test); ***P<0.001 vs DC and ### P<0.001 vs Hybrid+DC in B(One-way ANOVA Tukey’s multiple comparison); ***P<0.001 vs DC in I(two-tailed t-test); *P<0.05, **P<0.01 vs -IFN-γ/IL-1β and # P<0.05, ## P<0.01, ### P<0.001 vs -CK636/-Dy/-L77 in J-L(two-tailed t-test).

Article Snippet: To clarify the mechanism of membrane transfer between the two cell types, the hybrids were treated with nanotube inhibitors (L-778123, L77, MCE, HY-16273) and migrasome inhibitors (Dynasore, Dy, MCE HY-15304 and CK636, MCE HY-15892) for 8 hours prior to being co-cultured with iDCs for another 24 hours.

Techniques: Flow Cytometry, Membrane, Co-Culture Assay, Live Cell Imaging, Migration, Two Tailed Test, Comparison