HY-150091 Search Results


fuscoside  (MedChemExpress)
90
MedChemExpress fuscoside
Fuscoside, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/fuscoside/product/MedChemExpress
Average 90 stars, based on 1 article reviews
fuscoside - by Bioz Stars, 2026-02
90/100 stars
  Buy from Supplier
ye6144 in dmso  (MedChemExpress)
93
MedChemExpress ye6144 in dmso
A) Experimental design for testing the IRF5 inhibitor <t>YE6144</t> on neuronal survival and gene expression in vitro . B) Representative images of cortical neurons cultured in the presence of control media or PBMC-CM, and DMSO or YE6144. C) Neuronal cell counts after treatment with control media or PBMC-CM, and DMSO or YE6144. ** p < 0.01, *** p < 0.001, Two-way Anova with Holm-Sidak multiple comparison correction. D) Single sample gene set enrichment score for the list of 48 genes from from RNA-sequencing results of neurons after treatment with control or PBMC-CM and DMSO or YE6144. Two-way Anova with Holm-Sidak multiple comparison correction. E,F) Visualization of a subset of the 48 genes that are significantly dysregulated when comparing either PBMC-CM + DMSO to control media + DMSO, or PBMC-CM + YE6144 vs PBMC-CM + DMSO # = padj < 0.1, * = pval < 0.05.
Ye6144 In Dmso, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ye6144 in dmso/product/MedChemExpress
Average 93 stars, based on 1 article reviews
ye6144 in dmso - by Bioz Stars, 2026-02
93/100 stars
  Buy from Supplier
erf1 inhibitor  (MedChemExpress)
93
MedChemExpress erf1 inhibitor
A) Experimental design for testing the IRF5 inhibitor <t>YE6144</t> on neuronal survival and gene expression in vitro . B) Representative images of cortical neurons cultured in the presence of control media or PBMC-CM, and DMSO or YE6144. C) Neuronal cell counts after treatment with control media or PBMC-CM, and DMSO or YE6144. ** p < 0.01, *** p < 0.001, Two-way Anova with Holm-Sidak multiple comparison correction. D) Single sample gene set enrichment score for the list of 48 genes from from RNA-sequencing results of neurons after treatment with control or PBMC-CM and DMSO or YE6144. Two-way Anova with Holm-Sidak multiple comparison correction. E,F) Visualization of a subset of the 48 genes that are significantly dysregulated when comparing either PBMC-CM + DMSO to control media + DMSO, or PBMC-CM + YE6144 vs PBMC-CM + DMSO # = padj < 0.1, * = pval < 0.05.
Erf1 Inhibitor, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/erf1 inhibitor/product/MedChemExpress
Average 93 stars, based on 1 article reviews
erf1 inhibitor - by Bioz Stars, 2026-02
93/100 stars
  Buy from Supplier
recombinant human albumin  (MedChemExpress)
92
MedChemExpress recombinant human albumin
A) Experimental design for testing the IRF5 inhibitor <t>YE6144</t> on neuronal survival and gene expression in vitro . B) Representative images of cortical neurons cultured in the presence of control media or PBMC-CM, and DMSO or YE6144. C) Neuronal cell counts after treatment with control media or PBMC-CM, and DMSO or YE6144. ** p < 0.01, *** p < 0.001, Two-way Anova with Holm-Sidak multiple comparison correction. D) Single sample gene set enrichment score for the list of 48 genes from from RNA-sequencing results of neurons after treatment with control or PBMC-CM and DMSO or YE6144. Two-way Anova with Holm-Sidak multiple comparison correction. E,F) Visualization of a subset of the 48 genes that are significantly dysregulated when comparing either PBMC-CM + DMSO to control media + DMSO, or PBMC-CM + YE6144 vs PBMC-CM + DMSO # = padj < 0.1, * = pval < 0.05.
Recombinant Human Albumin, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/recombinant human albumin/product/MedChemExpress
Average 92 stars, based on 1 article reviews
recombinant human albumin - by Bioz Stars, 2026-02
92/100 stars
  Buy from Supplier

Image Search Results


A) Experimental design for testing the IRF5 inhibitor YE6144 on neuronal survival and gene expression in vitro . B) Representative images of cortical neurons cultured in the presence of control media or PBMC-CM, and DMSO or YE6144. C) Neuronal cell counts after treatment with control media or PBMC-CM, and DMSO or YE6144. ** p < 0.01, *** p < 0.001, Two-way Anova with Holm-Sidak multiple comparison correction. D) Single sample gene set enrichment score for the list of 48 genes from from RNA-sequencing results of neurons after treatment with control or PBMC-CM and DMSO or YE6144. Two-way Anova with Holm-Sidak multiple comparison correction. E,F) Visualization of a subset of the 48 genes that are significantly dysregulated when comparing either PBMC-CM + DMSO to control media + DMSO, or PBMC-CM + YE6144 vs PBMC-CM + DMSO # = padj < 0.1, * = pval < 0.05.

Journal: bioRxiv

Article Title: Uncovering immune characteristics of neurons in the context of multiple sclerosis and experimental autoimmune encephalomyelitis

doi: 10.1101/2024.08.19.608118

Figure Lengend Snippet: A) Experimental design for testing the IRF5 inhibitor YE6144 on neuronal survival and gene expression in vitro . B) Representative images of cortical neurons cultured in the presence of control media or PBMC-CM, and DMSO or YE6144. C) Neuronal cell counts after treatment with control media or PBMC-CM, and DMSO or YE6144. ** p < 0.01, *** p < 0.001, Two-way Anova with Holm-Sidak multiple comparison correction. D) Single sample gene set enrichment score for the list of 48 genes from from RNA-sequencing results of neurons after treatment with control or PBMC-CM and DMSO or YE6144. Two-way Anova with Holm-Sidak multiple comparison correction. E,F) Visualization of a subset of the 48 genes that are significantly dysregulated when comparing either PBMC-CM + DMSO to control media + DMSO, or PBMC-CM + YE6144 vs PBMC-CM + DMSO # = padj < 0.1, * = pval < 0.05.

Article Snippet: Cells were maintained in Neurobasal for 7 days, at which point a half media swap was conducted with either control media or stimulated PBMC-CM, containing DMSO or a final concentration of 1 uM of YE6144 in DMSO (MedChem Express, Cat. No.: HY-150095).

Techniques: Expressing, In Vitro, Cell Culture, Control, Comparison, RNA Sequencing Assay