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nachr agonist monepantel  (MedChemExpress)
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MedChemExpress nachr agonist monepantel
Effects of α7nAChR agonists in the treatment of LPS-induced lung injury. a The therapeutic effects of peripheral <t>nAChR</t> agonist <t>monepantel</t> and the peripheral nAChR antagonist vinblastine in acute lung injury were investigated. b Representative H&E staining was performed on lung samples from each group. Photographs of at least 6 sections of each tissue sample were taken. Scale bars, 100 μm. c The degree of lung injury was calculated and quantitatively analyzed according to the results of H&E staining, and the infiltration of leukocytes into BALF was compared among the groups; n = 6. d CXCL15, IL-1β, TNF-α, IL-6 ELISA kits were used to determine BALF inflammatory concentrations; n = 6. e Representative H&E staining was performed on lung samples from each group. Photographs of at least 6 sections of each tissue sample were taken. Scale bars, 100 μm. f The degree of lung injury was calculated and quantitatively analyzed according to the results of H&E staining, and the infiltration of leukocytes into BALF was compared among the groups; n = 6. g CXCL15, IL-1β, TNF-α, IL-6 ELISA kits were used to determine BALF inflammatory concentrations; n = 6
Nachr Agonist Monepantel, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Effects of α7nAChR agonists in the treatment of LPS-induced lung injury. a The therapeutic effects of peripheral nAChR agonist monepantel and the peripheral nAChR antagonist vinblastine in acute lung injury were investigated. b Representative H&E staining was performed on lung samples from each group. Photographs of at least 6 sections of each tissue sample were taken. Scale bars, 100 μm. c The degree of lung injury was calculated and quantitatively analyzed according to the results of H&E staining, and the infiltration of leukocytes into BALF was compared among the groups; n = 6. d CXCL15, IL-1β, TNF-α, IL-6 ELISA kits were used to determine BALF inflammatory concentrations; n = 6. e Representative H&E staining was performed on lung samples from each group. Photographs of at least 6 sections of each tissue sample were taken. Scale bars, 100 μm. f The degree of lung injury was calculated and quantitatively analyzed according to the results of H&E staining, and the infiltration of leukocytes into BALF was compared among the groups; n = 6. g CXCL15, IL-1β, TNF-α, IL-6 ELISA kits were used to determine BALF inflammatory concentrations; n = 6

Journal: Signal Transduction and Targeted Therapy

Article Title: Mesenchymal stromal cells alleviate acute respiratory distress syndrome through the cholinergic anti-inflammatory pathway

doi: 10.1038/s41392-022-01124-6

Figure Lengend Snippet: Effects of α7nAChR agonists in the treatment of LPS-induced lung injury. a The therapeutic effects of peripheral nAChR agonist monepantel and the peripheral nAChR antagonist vinblastine in acute lung injury were investigated. b Representative H&E staining was performed on lung samples from each group. Photographs of at least 6 sections of each tissue sample were taken. Scale bars, 100 μm. c The degree of lung injury was calculated and quantitatively analyzed according to the results of H&E staining, and the infiltration of leukocytes into BALF was compared among the groups; n = 6. d CXCL15, IL-1β, TNF-α, IL-6 ELISA kits were used to determine BALF inflammatory concentrations; n = 6. e Representative H&E staining was performed on lung samples from each group. Photographs of at least 6 sections of each tissue sample were taken. Scale bars, 100 μm. f The degree of lung injury was calculated and quantitatively analyzed according to the results of H&E staining, and the infiltration of leukocytes into BALF was compared among the groups; n = 6. g CXCL15, IL-1β, TNF-α, IL-6 ELISA kits were used to determine BALF inflammatory concentrations; n = 6

Article Snippet: The peripheral mAChR agonist Arecoline hydrobromide, mAChR antagonist Methylbenactyzium bromide, and nAChR agonist Monepantel, nAChR antagonist Vinblastine were obtained from MedChem Express (New Jersey, USA).

Techniques: Staining, Enzyme-linked Immunosorbent Assay