HY-144436 Search Results


xmd8 92  (MedChemExpress)
94
MedChemExpress xmd8 92
A Cells were treated for 24 h with 2c (2.5 µmol/L), Doxorubicin (25 nmol/L), Gemcitabine (10 nmol/L), MK2206 (10 μmol/L), <t>XMD8-92</t> (1 μmol/L), Torin1 (100 nmol/L), YKL-06-061 (1 μmol/L), Selumetinib (1 μmol/L), SAHA (2.5 μmol/L), TMP195 (20 μmol/L), NKL54 (5 μmol/L), Bafilomycin A1 (1 μmol/L), Chloroquine (1 μmol/L), ABT199 (100 nmol/L), ABT263 (100 nmol/L), MKC3946 (10 μmol/L), as indicated. B SK-UT-1 cells were treated for 4 h with 2c (2.5 µmol/L) Torin1 (100 nmol/L), YKL-06-061 (1 μmol/L), Chloroquine (1 μmol/L), ABT263 (100 nmol/L), or MKC3946 (10 μmol/L), as indicated. Immunoblots were performed using the indicated antibodies. Actin was used as a loading control. C Agarose gel electrophoresis of RT-PCR products for the full-length XBP1 transcript ( XBP1u ) and the spliced form ( XBP1s ). Samples were from SK-UT-1 treated with 2c (5 or 10 μmol/L) alone or in combination with MKC3946 (10 μmol/L) for 4 h. β-Actin was used as control. D mRNA levels expression of HSPA1A and HSPA6 in SK-UT-1 cells treated with 2c (5 or 10 μmol/L) alone or in combination with MKC3946 (10 μmol/L) for 4 h. E Cell death in SK-UT-1 cells after 24 h of incubation with the indicated concentrations of 2c in the presence or not of MKC3946 (10 μmol/L).
Xmd8 92, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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hy  (MedChemExpress)
93
MedChemExpress hy
A Cells were treated for 24 h with 2c (2.5 µmol/L), Doxorubicin (25 nmol/L), Gemcitabine (10 nmol/L), MK2206 (10 μmol/L), <t>XMD8-92</t> (1 μmol/L), Torin1 (100 nmol/L), YKL-06-061 (1 μmol/L), Selumetinib (1 μmol/L), SAHA (2.5 μmol/L), TMP195 (20 μmol/L), NKL54 (5 μmol/L), Bafilomycin A1 (1 μmol/L), Chloroquine (1 μmol/L), ABT199 (100 nmol/L), ABT263 (100 nmol/L), MKC3946 (10 μmol/L), as indicated. B SK-UT-1 cells were treated for 4 h with 2c (2.5 µmol/L) Torin1 (100 nmol/L), YKL-06-061 (1 μmol/L), Chloroquine (1 μmol/L), ABT263 (100 nmol/L), or MKC3946 (10 μmol/L), as indicated. Immunoblots were performed using the indicated antibodies. Actin was used as a loading control. C Agarose gel electrophoresis of RT-PCR products for the full-length XBP1 transcript ( XBP1u ) and the spliced form ( XBP1s ). Samples were from SK-UT-1 treated with 2c (5 or 10 μmol/L) alone or in combination with MKC3946 (10 μmol/L) for 4 h. β-Actin was used as control. D mRNA levels expression of HSPA1A and HSPA6 in SK-UT-1 cells treated with 2c (5 or 10 μmol/L) alone or in combination with MKC3946 (10 μmol/L) for 4 h. E Cell death in SK-UT-1 cells after 24 h of incubation with the indicated concentrations of 2c in the presence or not of MKC3946 (10 μmol/L).
Hy, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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hts07545  (MedChemExpress)
94
MedChemExpress hts07545
A Cells were treated for 24 h with 2c (2.5 µmol/L), Doxorubicin (25 nmol/L), Gemcitabine (10 nmol/L), MK2206 (10 μmol/L), <t>XMD8-92</t> (1 μmol/L), Torin1 (100 nmol/L), YKL-06-061 (1 μmol/L), Selumetinib (1 μmol/L), SAHA (2.5 μmol/L), TMP195 (20 μmol/L), NKL54 (5 μmol/L), Bafilomycin A1 (1 μmol/L), Chloroquine (1 μmol/L), ABT199 (100 nmol/L), ABT263 (100 nmol/L), MKC3946 (10 μmol/L), as indicated. B SK-UT-1 cells were treated for 4 h with 2c (2.5 µmol/L) Torin1 (100 nmol/L), YKL-06-061 (1 μmol/L), Chloroquine (1 μmol/L), ABT263 (100 nmol/L), or MKC3946 (10 μmol/L), as indicated. Immunoblots were performed using the indicated antibodies. Actin was used as a loading control. C Agarose gel electrophoresis of RT-PCR products for the full-length XBP1 transcript ( XBP1u ) and the spliced form ( XBP1s ). Samples were from SK-UT-1 treated with 2c (5 or 10 μmol/L) alone or in combination with MKC3946 (10 μmol/L) for 4 h. β-Actin was used as control. D mRNA levels expression of HSPA1A and HSPA6 in SK-UT-1 cells treated with 2c (5 or 10 μmol/L) alone or in combination with MKC3946 (10 μmol/L) for 4 h. E Cell death in SK-UT-1 cells after 24 h of incubation with the indicated concentrations of 2c in the presence or not of MKC3946 (10 μmol/L).
Hts07545, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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hts07545 - by Bioz Stars, 2026-02
94/100 stars
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Image Search Results


A Cells were treated for 24 h with 2c (2.5 µmol/L), Doxorubicin (25 nmol/L), Gemcitabine (10 nmol/L), MK2206 (10 μmol/L), XMD8-92 (1 μmol/L), Torin1 (100 nmol/L), YKL-06-061 (1 μmol/L), Selumetinib (1 μmol/L), SAHA (2.5 μmol/L), TMP195 (20 μmol/L), NKL54 (5 μmol/L), Bafilomycin A1 (1 μmol/L), Chloroquine (1 μmol/L), ABT199 (100 nmol/L), ABT263 (100 nmol/L), MKC3946 (10 μmol/L), as indicated. B SK-UT-1 cells were treated for 4 h with 2c (2.5 µmol/L) Torin1 (100 nmol/L), YKL-06-061 (1 μmol/L), Chloroquine (1 μmol/L), ABT263 (100 nmol/L), or MKC3946 (10 μmol/L), as indicated. Immunoblots were performed using the indicated antibodies. Actin was used as a loading control. C Agarose gel electrophoresis of RT-PCR products for the full-length XBP1 transcript ( XBP1u ) and the spliced form ( XBP1s ). Samples were from SK-UT-1 treated with 2c (5 or 10 μmol/L) alone or in combination with MKC3946 (10 μmol/L) for 4 h. β-Actin was used as control. D mRNA levels expression of HSPA1A and HSPA6 in SK-UT-1 cells treated with 2c (5 or 10 μmol/L) alone or in combination with MKC3946 (10 μmol/L) for 4 h. E Cell death in SK-UT-1 cells after 24 h of incubation with the indicated concentrations of 2c in the presence or not of MKC3946 (10 μmol/L).

Journal: Cell Death Discovery

Article Title: Proteotoxic stress-induced apoptosis in cancer cells: understanding the susceptibility and enhancing the potency

doi: 10.1038/s41420-022-01202-2

Figure Lengend Snippet: A Cells were treated for 24 h with 2c (2.5 µmol/L), Doxorubicin (25 nmol/L), Gemcitabine (10 nmol/L), MK2206 (10 μmol/L), XMD8-92 (1 μmol/L), Torin1 (100 nmol/L), YKL-06-061 (1 μmol/L), Selumetinib (1 μmol/L), SAHA (2.5 μmol/L), TMP195 (20 μmol/L), NKL54 (5 μmol/L), Bafilomycin A1 (1 μmol/L), Chloroquine (1 μmol/L), ABT199 (100 nmol/L), ABT263 (100 nmol/L), MKC3946 (10 μmol/L), as indicated. B SK-UT-1 cells were treated for 4 h with 2c (2.5 µmol/L) Torin1 (100 nmol/L), YKL-06-061 (1 μmol/L), Chloroquine (1 μmol/L), ABT263 (100 nmol/L), or MKC3946 (10 μmol/L), as indicated. Immunoblots were performed using the indicated antibodies. Actin was used as a loading control. C Agarose gel electrophoresis of RT-PCR products for the full-length XBP1 transcript ( XBP1u ) and the spliced form ( XBP1s ). Samples were from SK-UT-1 treated with 2c (5 or 10 μmol/L) alone or in combination with MKC3946 (10 μmol/L) for 4 h. β-Actin was used as control. D mRNA levels expression of HSPA1A and HSPA6 in SK-UT-1 cells treated with 2c (5 or 10 μmol/L) alone or in combination with MKC3946 (10 μmol/L) for 4 h. E Cell death in SK-UT-1 cells after 24 h of incubation with the indicated concentrations of 2c in the presence or not of MKC3946 (10 μmol/L).

Article Snippet: The following chemicals were used: 2c [ ], dimethyl sulfoxide (DMSO), Doxorubicin, MK2206, Torin1, Bafilomycin A1, Chloroquine, ABT263 (Sigma), Gemcitabine, XMD8-92, YKL-06-061, ABT199 (CSN Scientific), Selumetinib, TMP195, MKC3946 (MedChemExpress), SAHA (Cayman Chemicals), NKL54 [ ].

Techniques: Western Blot, Control, Agarose Gel Electrophoresis, Reverse Transcription Polymerase Chain Reaction, Expressing, Incubation