HY-13204R Search Results


在药物制备过程中  (MedChemExpress)
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MedChemExpress 在药物制备过程中
The effect of AH on the neurobehaviors in VD rats AH对VD大鼠神经行为的影响 VD group: vascular dementia model group; AH-L group: AH 10 μg/mL treatment group; AH-M group: AH <t>20</t> μg/mL treatment group; AH-H group: AB 40 μg/mL treatment group. A, The Bederson Test was performed; B, the pole climbing test was performed. * P < 0.05, ** P < 0.01, *** P < 0.001, vs. Sham group; & P < 0.05, && P < 0.01, vs. VD group. n = 4.
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The effect of AH on the neurobehaviors in VD rats AH对VD大鼠神经行为的影响 VD group: vascular dementia model group; AH-L group: AH 10 μg/mL treatment group; AH-M group: AH 20 μg/mL treatment group; AH-H group: AB 40 μg/mL treatment group. A, The Bederson Test was performed; B, the pole climbing test was performed. * P < 0.05, ** P < 0.01, *** P < 0.001, vs. Sham group; & P < 0.05, && P < 0.01, vs. VD group. n = 4.

Journal: Journal of Sichuan University (Medical Sciences)

Article Title: 氢溴酸樟柳碱对血管性痴呆模型大鼠的神经保护作用及其抗氧化应激机制研究

doi: 10.12182/20250360505

Figure Lengend Snippet: The effect of AH on the neurobehaviors in VD rats AH对VD大鼠神经行为的影响 VD group: vascular dementia model group; AH-L group: AH 10 μg/mL treatment group; AH-M group: AH 20 μg/mL treatment group; AH-H group: AB 40 μg/mL treatment group. A, The Bederson Test was performed; B, the pole climbing test was performed. * P < 0.05, ** P < 0.01, *** P < 0.001, vs. Sham group; & P < 0.05, && P < 0.01, vs. VD group. n = 4.

Article Snippet: 在药物制备过程中,使用双蒸水制备20 mg/mL氢溴酸樟柳碱(批号为271101,成一制药),8.5 mol/L的M1抑制剂Biperiden Hydrochloride(HY-13204, MCE), 68 mmol/L 的M2抑制剂Gallamine Triethiodide(S2471, Selleck)。使用二甲基亚砜(DMSO, D2650, Sigma)制备46 mmol/L的M受体抑制剂Atropine(HY-B1205, MCE),16 mmol/L 的M3抑制剂Darifenacin HBr(S3144, Selleck),200 mmol/L的M4抑制剂Tropicamide(S1913, Selleck)和50 mmol/L的 M5抑制剂Aclidinium Bromide(S4031, Selleck),作为药物阳性对照。

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