HY-126326 Search Results


gne 2861  (MedChemExpress)
92
MedChemExpress gne 2861
Gne 2861, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/gne 2861/product/MedChemExpress
Average 92 stars, based on 1 article reviews
gne 2861 - by Bioz Stars, 2026-02
92/100 stars
  Buy from Supplier
tigecycline hydrochloride  (MedChemExpress)
93
MedChemExpress tigecycline hydrochloride
AMXT-1501 has excellent antibacterial activity against Gram-negative MDR bacteria. (a) Antibacterial activity of AMXT-1501 against K. pneumoniae , an ESBL-producing E. coli , and carbapenem-resistant Enterobacteriaceae (CRE) E. coli detected by time-killing assays; compared with meropenem (MER) or <t>tigecycline</t> (TIG); The dashed lines indicated the limit of detection of time-killing assays. Antibacterial activity of AMXT-1501 against abdominal infected with E. coli ECO2219 ( n = 15/group); compared with TIG. (b) The strategy of administration for mice abdominal infection model, (c) survival rates, bacteriology in lung (d) and liver (e) on day 7. Data in panels a, d and e were presented as means ± s.d, and P values were determined using an unpaired, two-tailed Student’s t-test. P values were determined using log-rank test for panels c. MER, meropenem; TIG, tigecycline; AMXT, AMXT-1501; MIC, minimum inhibitory concentration; ESBL, extended-spectrum β-lactamase; CRE, carbapenem-resistant Enterobacteriaceae.
Tigecycline Hydrochloride, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/tigecycline hydrochloride/product/MedChemExpress
Average 93 stars, based on 1 article reviews
tigecycline hydrochloride - by Bioz Stars, 2026-02
93/100 stars
  Buy from Supplier
azd9898  (MedChemExpress)
94
MedChemExpress azd9898
AMXT-1501 has excellent antibacterial activity against Gram-negative MDR bacteria. (a) Antibacterial activity of AMXT-1501 against K. pneumoniae , an ESBL-producing E. coli , and carbapenem-resistant Enterobacteriaceae (CRE) E. coli detected by time-killing assays; compared with meropenem (MER) or <t>tigecycline</t> (TIG); The dashed lines indicated the limit of detection of time-killing assays. Antibacterial activity of AMXT-1501 against abdominal infected with E. coli ECO2219 ( n = 15/group); compared with TIG. (b) The strategy of administration for mice abdominal infection model, (c) survival rates, bacteriology in lung (d) and liver (e) on day 7. Data in panels a, d and e were presented as means ± s.d, and P values were determined using an unpaired, two-tailed Student’s t-test. P values were determined using log-rank test for panels c. MER, meropenem; TIG, tigecycline; AMXT, AMXT-1501; MIC, minimum inhibitory concentration; ESBL, extended-spectrum β-lactamase; CRE, carbapenem-resistant Enterobacteriaceae.
Azd9898, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/azd9898/product/MedChemExpress
Average 94 stars, based on 1 article reviews
azd9898 - by Bioz Stars, 2026-02
94/100 stars
  Buy from Supplier
swe101  (MedChemExpress)
N/A
   Buy from Supplier

Image Search Results


AMXT-1501 has excellent antibacterial activity against Gram-negative MDR bacteria. (a) Antibacterial activity of AMXT-1501 against K. pneumoniae , an ESBL-producing E. coli , and carbapenem-resistant Enterobacteriaceae (CRE) E. coli detected by time-killing assays; compared with meropenem (MER) or tigecycline (TIG); The dashed lines indicated the limit of detection of time-killing assays. Antibacterial activity of AMXT-1501 against abdominal infected with E. coli ECO2219 ( n = 15/group); compared with TIG. (b) The strategy of administration for mice abdominal infection model, (c) survival rates, bacteriology in lung (d) and liver (e) on day 7. Data in panels a, d and e were presented as means ± s.d, and P values were determined using an unpaired, two-tailed Student’s t-test. P values were determined using log-rank test for panels c. MER, meropenem; TIG, tigecycline; AMXT, AMXT-1501; MIC, minimum inhibitory concentration; ESBL, extended-spectrum β-lactamase; CRE, carbapenem-resistant Enterobacteriaceae.

Journal: Emerging Microbes & Infections

Article Title: AMXT-1501 targets membrane phospholipids against Gram-positive and -negative multidrug-resistant bacteria

doi: 10.1080/22221751.2024.2321981

Figure Lengend Snippet: AMXT-1501 has excellent antibacterial activity against Gram-negative MDR bacteria. (a) Antibacterial activity of AMXT-1501 against K. pneumoniae , an ESBL-producing E. coli , and carbapenem-resistant Enterobacteriaceae (CRE) E. coli detected by time-killing assays; compared with meropenem (MER) or tigecycline (TIG); The dashed lines indicated the limit of detection of time-killing assays. Antibacterial activity of AMXT-1501 against abdominal infected with E. coli ECO2219 ( n = 15/group); compared with TIG. (b) The strategy of administration for mice abdominal infection model, (c) survival rates, bacteriology in lung (d) and liver (e) on day 7. Data in panels a, d and e were presented as means ± s.d, and P values were determined using an unpaired, two-tailed Student’s t-test. P values were determined using log-rank test for panels c. MER, meropenem; TIG, tigecycline; AMXT, AMXT-1501; MIC, minimum inhibitory concentration; ESBL, extended-spectrum β-lactamase; CRE, carbapenem-resistant Enterobacteriaceae.

Article Snippet: Oxacillin sodium (HY-B0465; 99.55%), ampicillin sodium (HY-B0522A; ≥ 98%), cefazolin sodium (HY-B1078; 95.45%), ceftriaxone sodium (HY-B0712B; 98.03%), cefepime (HY-B0692; 99.78%), imipenem (HY-B1369A; ≥ 98%), meropenem (HY-13678; ≥ 98%), levofloxacin hydrochloride (HY-B0330B; ≥ 98%), erythromycin (HY-B0220; 99.86%), azithromycin (HY-17506; ≥ 98%), doxycycline (HY-N0565; ≥ 98%), tigecycline hydrochloride (HY-B0117A; ≥ 98%), gentamicin (HY-A0276A; ≥ 98%), linezolid (HY-10394; 99.95%), daptomycin (HY-B0108; 99.90%), colistin (HY-113678; ≥ 98%), vancomycin (HY-B0671; 96.66%) were purchased from MedChemExpress (Shanghai, China).

Techniques: Activity Assay, Bacteria, Infection, Two Tailed Test, Concentration Assay