HY-114452 Search Results


ly2940094  (MedChemExpress)
93
MedChemExpress ly2940094
(A) Tg(-8.3 phox2bb :Kaede) embryos were exposed at 48 hpf for 48 hpe (hours post exposure) with the opioid inhibitors, <t>LY2940094,</t> curcumin and DADLE, all of them at 10 µM. (B, C, D, E) Confocal images reveal fluorescent labeled ENCCs/ENs along the gut in larvae that were treated with DMSO, LY2940094, curcumin and DADLE, respectively. Inhibitor-treated larvae show a reduction of Kaede + cells, compared with the DMSO control. Dashed purple lines surround the gut.
Ly2940094, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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(A) Tg(-8.3 phox2bb :Kaede) embryos were exposed at 48 hpf for 48 hpe (hours post exposure) with the opioid inhibitors, LY2940094, curcumin and DADLE, all of them at 10 µM. (B, C, D, E) Confocal images reveal fluorescent labeled ENCCs/ENs along the gut in larvae that were treated with DMSO, LY2940094, curcumin and DADLE, respectively. Inhibitor-treated larvae show a reduction of Kaede + cells, compared with the DMSO control. Dashed purple lines surround the gut.

Journal: bioRxiv

Article Title: A targeted CRISPR-Cas9 mediated F0 screen identifies genes involved in establishment of the enteric nervous system

doi: 10.1101/2023.12.28.573581

Figure Lengend Snippet: (A) Tg(-8.3 phox2bb :Kaede) embryos were exposed at 48 hpf for 48 hpe (hours post exposure) with the opioid inhibitors, LY2940094, curcumin and DADLE, all of them at 10 µM. (B, C, D, E) Confocal images reveal fluorescent labeled ENCCs/ENs along the gut in larvae that were treated with DMSO, LY2940094, curcumin and DADLE, respectively. Inhibitor-treated larvae show a reduction of Kaede + cells, compared with the DMSO control. Dashed purple lines surround the gut.

Article Snippet: LY2940094 (MedChemExpress, HY-114452), curcumin (sigma-aldrich, C1386) and DADLE (abcam, ab120673) master stocks were diluted in DMSO and then further diluted in 1xPTU/E3 medium to the required working concentration (10 µM).

Techniques: Labeling, Control