HY-104031 Search Results


idh305  (MedChemExpress)
92
MedChemExpress idh305
Inhibitors of IDH1 mutation reversed its effects on erastin-induced ferroptosis in cholangiocarcinoma RBE cell line. Current targeted inhibitors of IDH1 (AG120 and <t>IDH305)</t> were administrated into IDH1 R132C mutation cell line with erastin and DMSO treatment, and (a) cells were microscopically photographed. (b) The number of PI-positive cells was statistically quantified. (c) The trypan blue staining assay was used to determine the effects of AG120 or IDH305 on the cell viability. (d) The effects of AG120 or IDH305 on the lipid ROS levels were determined by using flow cytometer, and (d and e) statistically quantified. *** p < 0.001 vs DMSO treatment group.
Idh305, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/idh305/product/MedChemExpress
Average 92 stars, based on 1 article reviews
idh305 - by Bioz Stars, 2026-02
92/100 stars
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ac coa synthase inhibitor 1  (MedChemExpress)
94
MedChemExpress ac coa synthase inhibitor 1
Inhibitors of IDH1 mutation reversed its effects on erastin-induced ferroptosis in cholangiocarcinoma RBE cell line. Current targeted inhibitors of IDH1 (AG120 and <t>IDH305)</t> were administrated into IDH1 R132C mutation cell line with erastin and DMSO treatment, and (a) cells were microscopically photographed. (b) The number of PI-positive cells was statistically quantified. (c) The trypan blue staining assay was used to determine the effects of AG120 or IDH305 on the cell viability. (d) The effects of AG120 or IDH305 on the lipid ROS levels were determined by using flow cytometer, and (d and e) statistically quantified. *** p < 0.001 vs DMSO treatment group.
Ac Coa Synthase Inhibitor 1, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ac coa synthase inhibitor 1/product/MedChemExpress
Average 94 stars, based on 1 article reviews
ac coa synthase inhibitor 1 - by Bioz Stars, 2026-02
94/100 stars
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ph797804  (MedChemExpress)
92
MedChemExpress ph797804
Inhibitors of IDH1 mutation reversed its effects on erastin-induced ferroptosis in cholangiocarcinoma RBE cell line. Current targeted inhibitors of IDH1 (AG120 and <t>IDH305)</t> were administrated into IDH1 R132C mutation cell line with erastin and DMSO treatment, and (a) cells were microscopically photographed. (b) The number of PI-positive cells was statistically quantified. (c) The trypan blue staining assay was used to determine the effects of AG120 or IDH305 on the cell viability. (d) The effects of AG120 or IDH305 on the lipid ROS levels were determined by using flow cytometer, and (d and e) statistically quantified. *** p < 0.001 vs DMSO treatment group.
Ph797804, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ph797804/product/MedChemExpress
Average 92 stars, based on 1 article reviews
ph797804 - by Bioz Stars, 2026-02
92/100 stars
  Buy from Supplier
lyc 55716  (MedChemExpress)
93
MedChemExpress lyc 55716
Inhibitors of IDH1 mutation reversed its effects on erastin-induced ferroptosis in cholangiocarcinoma RBE cell line. Current targeted inhibitors of IDH1 (AG120 and <t>IDH305)</t> were administrated into IDH1 R132C mutation cell line with erastin and DMSO treatment, and (a) cells were microscopically photographed. (b) The number of PI-positive cells was statistically quantified. (c) The trypan blue staining assay was used to determine the effects of AG120 or IDH305 on the cell viability. (d) The effects of AG120 or IDH305 on the lipid ROS levels were determined by using flow cytometer, and (d and e) statistically quantified. *** p < 0.001 vs DMSO treatment group.
Lyc 55716, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/lyc 55716/product/MedChemExpress
Average 93 stars, based on 1 article reviews
lyc 55716 - by Bioz Stars, 2026-02
93/100 stars
  Buy from Supplier
tcfa15  (MedChemExpress)
N/A
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Image Search Results


Inhibitors of IDH1 mutation reversed its effects on erastin-induced ferroptosis in cholangiocarcinoma RBE cell line. Current targeted inhibitors of IDH1 (AG120 and IDH305) were administrated into IDH1 R132C mutation cell line with erastin and DMSO treatment, and (a) cells were microscopically photographed. (b) The number of PI-positive cells was statistically quantified. (c) The trypan blue staining assay was used to determine the effects of AG120 or IDH305 on the cell viability. (d) The effects of AG120 or IDH305 on the lipid ROS levels were determined by using flow cytometer, and (d and e) statistically quantified. *** p < 0.001 vs DMSO treatment group.

Journal: Open Medicine

Article Title: Isocitrate dehydrogenase 1 mutation in cholangiocarcinoma impairs tumor progression by sensitizing cells to ferroptosis

doi: 10.1515/med-2022-0477

Figure Lengend Snippet: Inhibitors of IDH1 mutation reversed its effects on erastin-induced ferroptosis in cholangiocarcinoma RBE cell line. Current targeted inhibitors of IDH1 (AG120 and IDH305) were administrated into IDH1 R132C mutation cell line with erastin and DMSO treatment, and (a) cells were microscopically photographed. (b) The number of PI-positive cells was statistically quantified. (c) The trypan blue staining assay was used to determine the effects of AG120 or IDH305 on the cell viability. (d) The effects of AG120 or IDH305 on the lipid ROS levels were determined by using flow cytometer, and (d and e) statistically quantified. *** p < 0.001 vs DMSO treatment group.

Article Snippet: AG-120 (CSNpharm), IDH305 (DC Chemicals), erastin (MedChemExpress, ME) were purchased commercially.

Techniques: Mutagenesis, Staining, Flow Cytometry