812-antibody microarray Search Results


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Figure 7. <t>a-ITGA7</t> Impairs GBM Tumor Growth and Invasion In Vivo (A) Luciferase activity detected with a Xenogen IVIS 100 small animal in vivo imaging system, 5 days post-sc transplantation of 5 X 105 GSC1-LUC cells in mice either treated with anti-ITGA7 (a-ITGA7) antibody or isotype control (i.p.). (B) Analysis of sc GSC1-LUC tumor growth over time in mice treated either with isotype control or with a-ITGA7 antibody (1.4A12). Shown is the average photon count and SEM of n = 6 mice/group measured by Xenogen IVIS 100small animal in vivo imaging system (***p< 0.001, two-tailed Student’s t test). See also FigureS7. (C) Analyses of the tumor volumes 5 months after ceasing the anti-ITGA7 treatment. Shown is the size of the sc tumors of n = 6 mice/group measured by calliper (**p < 0.01, two-tailed Student’s t test).
Itga7 Miltenyi Bioteck, supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Figure 7. a-ITGA7 Impairs GBM Tumor Growth and Invasion In Vivo (A) Luciferase activity detected with a Xenogen IVIS 100 small animal in vivo imaging system, 5 days post-sc transplantation of 5 X 105 GSC1-LUC cells in mice either treated with anti-ITGA7 (a-ITGA7) antibody or isotype control (i.p.). (B) Analysis of sc GSC1-LUC tumor growth over time in mice treated either with isotype control or with a-ITGA7 antibody (1.4A12). Shown is the average photon count and SEM of n = 6 mice/group measured by Xenogen IVIS 100small animal in vivo imaging system (***p< 0.001, two-tailed Student’s t test). See also FigureS7. (C) Analyses of the tumor volumes 5 months after ceasing the anti-ITGA7 treatment. Shown is the size of the sc tumors of n = 6 mice/group measured by calliper (**p < 0.01, two-tailed Student’s t test).

Journal: Cell stem cell

Article Title: Integrin α7 Is a Functional Marker and Potential Therapeutic Target in Glioblastoma.

doi: 10.1016/j.stem.2017.04.009

Figure Lengend Snippet: Figure 7. a-ITGA7 Impairs GBM Tumor Growth and Invasion In Vivo (A) Luciferase activity detected with a Xenogen IVIS 100 small animal in vivo imaging system, 5 days post-sc transplantation of 5 X 105 GSC1-LUC cells in mice either treated with anti-ITGA7 (a-ITGA7) antibody or isotype control (i.p.). (B) Analysis of sc GSC1-LUC tumor growth over time in mice treated either with isotype control or with a-ITGA7 antibody (1.4A12). Shown is the average photon count and SEM of n = 6 mice/group measured by Xenogen IVIS 100small animal in vivo imaging system (***p< 0.001, two-tailed Student’s t test). See also FigureS7. (C) Analyses of the tumor volumes 5 months after ceasing the anti-ITGA7 treatment. Shown is the size of the sc tumors of n = 6 mice/group measured by calliper (**p < 0.01, two-tailed Student’s t test).

Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER PE Mouse monoclonal anti EphA2 (clone 371805) R&D Cat#FAB3035P; RRID:AB_11128496 APC Mouse monoclonal anti CD44 BD Biosciences Cat# 560890 Mouse monoclonal anti CD44 (clone DF1485) DAKO Cat#M7082; RRID:AB_2076596 Mouse monoclonal anti ITGA7 Miltenyi Bioteck Cat#130-103-774 Mouse monoclonal anti murine ITGA7 (clone 6A11) Acris Cat#AM20012AF-N; Please See Table S3 for Reverse Phase Protein Microarray Antibodies used N/A N/A Biological Samples GSC (Glioblastoma Stem Cells) (Marziali et al., 2016; Ricci-Vitiani et al., 2008) N/A Chemicals, Peptides, and Recombinant Proteins EGF Peprotech Cat#100-15 bFGF Peprotech Cat#100-18B Apotransferrin Sigma Cat#T2252 Putrescine Sigma Cat#P5780 Sodium Selenite Sigma Cat#S5261 Bovine Serum Albumin Sigma Cat#A2153 Progesterone Sigma Cat#P8783 Insulin Sigma Cat#I3536 HAT Supplement 50X Thermo Scientific Cat#21060017 HT Supplement 100X Thermo Scientific Cat#11067030 BM Condimed H1 Hybridoma Suppl.

Techniques: In Vivo, Luciferase, Activity Assay, In Vivo Imaging, Transplantation Assay, Control, Two Tailed Test