Journal: Biomicrofluidics

Article Title: Toward a modular, integrated, miniaturized, and portable microfluidic flow control architecture for organs-on-chips applications

doi: 10.1063/5.0074156

Figure Lengend Snippet: Commercially available OoC devices, applications, and microfluidic complexities as shown in and their combinations.

Article Snippet: On-chip micropumps to create recirculation are controlled by external pressurized air or vacuum systems to provide pulsatile flow in these devices. table ft1 table-wrap mode="anchored" t5 TABLE II. caption a7 Company and OoC device name Applied tissue/organ/system Microfluidic complexity Representative image(s) Micronit Microtechnologies B.V. & IMEC Smart multi-electrode array-chip Complex tissue models, heart Single chamber and single channel AlveoliX AX12 Lung Single chamber and double channel PimBio B.V. PIMCELL Gut, 3D cell culture Bi/OND inCHIPit-3C TM 3D tissues Single chamber and multichannel Emulate Inc. Chip-S1 Lung, brain, kidney, liver, intestine Double chamber and multichannel Hesperos Inc. Human-on-a-chip 2-organ, 3-organ, and 4-organ models Multiple chambers and single channel InSphero Inc. Akura TM Multi-tissues Multiple chambers and double channel Mimetas B.V. OrganoPlate® 3D tissues and organ models3D co-culture of organotypic cells Multiple chambers and multichannel Nortis ParVivo TM SynVivo Inc. IMN 2&3 series (linear and radial) Lung, blood-brain barrier, cancer TissUse GmbH HUMIMIC TM 2-organ and 4-organ models Open in a separate window Commercially available OoC devices, applications, and microfluidic complexities as shown in and their combinations.

Techniques: Cell Culture