4 hydroperoxy cyclophosphamide Search Results


4 hc  (MedChemExpress)
94
MedChemExpress 4 hc
A Western blot results of the H3K27me3, H2AK119ub1, H3K9me3, H3K4me3, EZH2, and SUZ12 levels in the PBS and CTX groups. H3, GAPDH, and β-tubulin were blotted as loading controls. N = 6 mice per time point for each group. B – D Immunofluorescence staining of the ovaries collected 6 and 24 h after the i.p. injection of PBS or CTX. Rabbit monoclonal antibodies H3K27me3 ( B ), H3K9me3 ( C ), and EZH2 ( D ) were detected using anti-rabbit IgG (red). TUNEL was probed with Alexa Fluor 488 (green). Cell nuclei were labeled with DAPI (blue). Scale bar, 100 μm. N = 6 ovaries from different mice per time point for each group. E Western blot results for EZH2, H3K27me3, and γH2AX levels in the negative control (NC) <t>and</t> <t>4-HC</t> treatment groups. β-actin and H3 were blotted as loading controls. F Quantitative expression of Ezh2 in the siNC and si Ezh2 -1 + 2 + 3 groups. G Western blot results of EZH2, H3K27me3, and γH2AX levels in the siNC and si Ezh2 -1 + 2 + 3 groups. β-actin and H3 were blotted as loading controls. Data are the mean ± SD of at least three independent experiments. Statistical analyses were carried out using a two-tailed Student’s t -test; *** P < 0.001.
4 Hc, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/4+hydroperoxy+cyclophosphamide/4-Hydroperoxy+cyclophosphamide/pmc10646043-252-14-23
Average 94 stars, based on 1 article reviews
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cells  (Santa Cruz Biotechnology)
93
Santa Cruz Biotechnology cells
A Western blot results of the H3K27me3, H2AK119ub1, H3K9me3, H3K4me3, EZH2, and SUZ12 levels in the PBS and CTX groups. H3, GAPDH, and β-tubulin were blotted as loading controls. N = 6 mice per time point for each group. B – D Immunofluorescence staining of the ovaries collected 6 and 24 h after the i.p. injection of PBS or CTX. Rabbit monoclonal antibodies H3K27me3 ( B ), H3K9me3 ( C ), and EZH2 ( D ) were detected using anti-rabbit IgG (red). TUNEL was probed with Alexa Fluor 488 (green). Cell nuclei were labeled with DAPI (blue). Scale bar, 100 μm. N = 6 ovaries from different mice per time point for each group. E Western blot results for EZH2, H3K27me3, and γH2AX levels in the negative control (NC) <t>and</t> <t>4-HC</t> treatment groups. β-actin and H3 were blotted as loading controls. F Quantitative expression of Ezh2 in the siNC and si Ezh2 -1 + 2 + 3 groups. G Western blot results of EZH2, H3K27me3, and γH2AX levels in the siNC and si Ezh2 -1 + 2 + 3 groups. β-actin and H3 were blotted as loading controls. Data are the mean ± SD of at least three independent experiments. Statistical analyses were carried out using a two-tailed Student’s t -test; *** P < 0.001.
Cells, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
cells - by Bioz Stars, 2026-10
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4 hydroperoxy cyclophosphamide  (Toronto Research Chemicals)
91
Toronto Research Chemicals 4 hydroperoxy cyclophosphamide
A Western blot results of the H3K27me3, H2AK119ub1, H3K9me3, H3K4me3, EZH2, and SUZ12 levels in the PBS and CTX groups. H3, GAPDH, and β-tubulin were blotted as loading controls. N = 6 mice per time point for each group. B – D Immunofluorescence staining of the ovaries collected 6 and 24 h after the i.p. injection of PBS or CTX. Rabbit monoclonal antibodies H3K27me3 ( B ), H3K9me3 ( C ), and EZH2 ( D ) were detected using anti-rabbit IgG (red). TUNEL was probed with Alexa Fluor 488 (green). Cell nuclei were labeled with DAPI (blue). Scale bar, 100 μm. N = 6 ovaries from different mice per time point for each group. E Western blot results for EZH2, H3K27me3, and γH2AX levels in the negative control (NC) <t>and</t> <t>4-HC</t> treatment groups. β-actin and H3 were blotted as loading controls. F Quantitative expression of Ezh2 in the siNC and si Ezh2 -1 + 2 + 3 groups. G Western blot results of EZH2, H3K27me3, and γH2AX levels in the siNC and si Ezh2 -1 + 2 + 3 groups. β-actin and H3 were blotted as loading controls. Data are the mean ± SD of at least three independent experiments. Statistical analyses were carried out using a two-tailed Student’s t -test; *** P < 0.001.
4 Hydroperoxy Cyclophosphamide, supplied by Toronto Research Chemicals, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/4+hydroperoxy+cyclophosphamide/4-Hydroperoxy+Cyclophosphamide/pmc04723671-141-0-8
Average 91 stars, based on 1 article reviews
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4 hydroperoxycyclophosphamide  (Toronto Research Chemicals)
92
Toronto Research Chemicals 4 hydroperoxycyclophosphamide
A Western blot results of the H3K27me3, H2AK119ub1, H3K9me3, H3K4me3, EZH2, and SUZ12 levels in the PBS and CTX groups. H3, GAPDH, and β-tubulin were blotted as loading controls. N = 6 mice per time point for each group. B – D Immunofluorescence staining of the ovaries collected 6 and 24 h after the i.p. injection of PBS or CTX. Rabbit monoclonal antibodies H3K27me3 ( B ), H3K9me3 ( C ), and EZH2 ( D ) were detected using anti-rabbit IgG (red). TUNEL was probed with Alexa Fluor 488 (green). Cell nuclei were labeled with DAPI (blue). Scale bar, 100 μm. N = 6 ovaries from different mice per time point for each group. E Western blot results for EZH2, H3K27me3, and γH2AX levels in the negative control (NC) <t>and</t> <t>4-HC</t> treatment groups. β-actin and H3 were blotted as loading controls. F Quantitative expression of Ezh2 in the siNC and si Ezh2 -1 + 2 + 3 groups. G Western blot results of EZH2, H3K27me3, and γH2AX levels in the siNC and si Ezh2 -1 + 2 + 3 groups. β-actin and H3 were blotted as loading controls. Data are the mean ± SD of at least three independent experiments. Statistical analyses were carried out using a two-tailed Student’s t -test; *** P < 0.001.
4 Hydroperoxycyclophosphamide, supplied by Toronto Research Chemicals, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/4+hydroperoxy+cyclophosphamide/4-Hydroperoxy+Cyclophosphamide/pmc05916087-48-11-13
Average 92 stars, based on 1 article reviews
4 hydroperoxycyclophosphamide - by Bioz Stars, 2026-10
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4-hydroperoxy cyclophosphamide  (ApexBio)
90
ApexBio 4-hydroperoxy cyclophosphamide
A Western blot results of the H3K27me3, H2AK119ub1, H3K9me3, H3K4me3, EZH2, and SUZ12 levels in the PBS and CTX groups. H3, GAPDH, and β-tubulin were blotted as loading controls. N = 6 mice per time point for each group. B – D Immunofluorescence staining of the ovaries collected 6 and 24 h after the i.p. injection of PBS or CTX. Rabbit monoclonal antibodies H3K27me3 ( B ), H3K9me3 ( C ), and EZH2 ( D ) were detected using anti-rabbit IgG (red). TUNEL was probed with Alexa Fluor 488 (green). Cell nuclei were labeled with DAPI (blue). Scale bar, 100 μm. N = 6 ovaries from different mice per time point for each group. E Western blot results for EZH2, H3K27me3, and γH2AX levels in the negative control (NC) <t>and</t> <t>4-HC</t> treatment groups. β-actin and H3 were blotted as loading controls. F Quantitative expression of Ezh2 in the siNC and si Ezh2 -1 + 2 + 3 groups. G Western blot results of EZH2, H3K27me3, and γH2AX levels in the siNC and si Ezh2 -1 + 2 + 3 groups. β-actin and H3 were blotted as loading controls. Data are the mean ± SD of at least three independent experiments. Statistical analyses were carried out using a two-tailed Student’s t -test; *** P < 0.001.
4 Hydroperoxy Cyclophosphamide, supplied by ApexBio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/4+hydroperoxy+cyclophosphamide/4+hydroperoxy+cyclophosphamide/pmc06341729-71-4-9
Average 90 stars, based on 1 article reviews
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4-hydroperoxy cyclophosphamide  (US Biological Life Sciences)
90
US Biological Life Sciences 4-hydroperoxy cyclophosphamide
A Western blot results of the H3K27me3, H2AK119ub1, H3K9me3, H3K4me3, EZH2, and SUZ12 levels in the PBS and CTX groups. H3, GAPDH, and β-tubulin were blotted as loading controls. N = 6 mice per time point for each group. B – D Immunofluorescence staining of the ovaries collected 6 and 24 h after the i.p. injection of PBS or CTX. Rabbit monoclonal antibodies H3K27me3 ( B ), H3K9me3 ( C ), and EZH2 ( D ) were detected using anti-rabbit IgG (red). TUNEL was probed with Alexa Fluor 488 (green). Cell nuclei were labeled with DAPI (blue). Scale bar, 100 μm. N = 6 ovaries from different mice per time point for each group. E Western blot results for EZH2, H3K27me3, and γH2AX levels in the negative control (NC) <t>and</t> <t>4-HC</t> treatment groups. β-actin and H3 were blotted as loading controls. F Quantitative expression of Ezh2 in the siNC and si Ezh2 -1 + 2 + 3 groups. G Western blot results of EZH2, H3K27me3, and γH2AX levels in the siNC and si Ezh2 -1 + 2 + 3 groups. β-actin and H3 were blotted as loading controls. Data are the mean ± SD of at least three independent experiments. Statistical analyses were carried out using a two-tailed Student’s t -test; *** P < 0.001.
4 Hydroperoxy Cyclophosphamide, supplied by US Biological Life Sciences, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/4+hydroperoxy+cyclophosphamide/4+hydroperoxy+cyclophosphamide/pmc11273629-85-10-13
Average 90 stars, based on 1 article reviews
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4-hydroperoxy cyclophosphamide 4-hc  (US Biological Life Sciences)
90
US Biological Life Sciences 4-hydroperoxy cyclophosphamide 4-hc
A Western blot results of the H3K27me3, H2AK119ub1, H3K9me3, H3K4me3, EZH2, and SUZ12 levels in the PBS and CTX groups. H3, GAPDH, and β-tubulin were blotted as loading controls. N = 6 mice per time point for each group. B – D Immunofluorescence staining of the ovaries collected 6 and 24 h after the i.p. injection of PBS or CTX. Rabbit monoclonal antibodies H3K27me3 ( B ), H3K9me3 ( C ), and EZH2 ( D ) were detected using anti-rabbit IgG (red). TUNEL was probed with Alexa Fluor 488 (green). Cell nuclei were labeled with DAPI (blue). Scale bar, 100 μm. N = 6 ovaries from different mice per time point for each group. E Western blot results for EZH2, H3K27me3, and γH2AX levels in the negative control (NC) <t>and</t> <t>4-HC</t> treatment groups. β-actin and H3 were blotted as loading controls. F Quantitative expression of Ezh2 in the siNC and si Ezh2 -1 + 2 + 3 groups. G Western blot results of EZH2, H3K27me3, and γH2AX levels in the siNC and si Ezh2 -1 + 2 + 3 groups. β-actin and H3 were blotted as loading controls. Data are the mean ± SD of at least three independent experiments. Statistical analyses were carried out using a two-tailed Student’s t -test; *** P < 0.001.
4 Hydroperoxy Cyclophosphamide 4 Hc, supplied by US Biological Life Sciences, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/4+hydroperoxy+cyclophosphamide/4+hydroperoxy+cyclophosphamide+4+hc/pm39061895-85-10-13
Average 90 stars, based on 1 article reviews
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4-hydroperoxy cyclophosphamide-d4  (Santa Cruz Biotechnology)
N/A
4-Hydroperoxy Cyclophosphamide-d4 is a labeled metabolite of Cyclophosphamide. Also an antineoplastic, bone marrow purging agent.
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4-hydroperoxy cyclophosphamide  (1PlusChem LLC)
N/A
4-HYDROPEROXY CYCLOPHOSPHAMIDE
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4-hydroperoxy cyclophosphamide  (Aladdin Scientific Corporation)
N/A
4-Hydroperoxy cyclophosphamide is the active metabolite form of the proagent Cyclophosphamide. 4-Hydroperoxy cyclophosphamide crosslinks DNA and induces T cell apoptosis independent of death receptor activation, but activates mitochondrial death pathways through production of reactive oxygen
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4-hydroperoxy cyclophosphamide-d4  (Toronto Research Chemicals)
N/A
4-Hydroperoxy Cyclophosphamide-d4
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Image Search Results


A Western blot results of the H3K27me3, H2AK119ub1, H3K9me3, H3K4me3, EZH2, and SUZ12 levels in the PBS and CTX groups. H3, GAPDH, and β-tubulin were blotted as loading controls. N = 6 mice per time point for each group. B – D Immunofluorescence staining of the ovaries collected 6 and 24 h after the i.p. injection of PBS or CTX. Rabbit monoclonal antibodies H3K27me3 ( B ), H3K9me3 ( C ), and EZH2 ( D ) were detected using anti-rabbit IgG (red). TUNEL was probed with Alexa Fluor 488 (green). Cell nuclei were labeled with DAPI (blue). Scale bar, 100 μm. N = 6 ovaries from different mice per time point for each group. E Western blot results for EZH2, H3K27me3, and γH2AX levels in the negative control (NC) and 4-HC treatment groups. β-actin and H3 were blotted as loading controls. F Quantitative expression of Ezh2 in the siNC and si Ezh2 -1 + 2 + 3 groups. G Western blot results of EZH2, H3K27me3, and γH2AX levels in the siNC and si Ezh2 -1 + 2 + 3 groups. β-actin and H3 were blotted as loading controls. Data are the mean ± SD of at least three independent experiments. Statistical analyses were carried out using a two-tailed Student’s t -test; *** P < 0.001.

Journal: Cell Death Discovery

Article Title: The EZH2-H3K27me3 axis modulates aberrant transcription and apoptosis in cyclophosphamide-induced ovarian granulosa cell injury

doi: 10.1038/s41420-023-01705-6

Figure Lengend Snippet: A Western blot results of the H3K27me3, H2AK119ub1, H3K9me3, H3K4me3, EZH2, and SUZ12 levels in the PBS and CTX groups. H3, GAPDH, and β-tubulin were blotted as loading controls. N = 6 mice per time point for each group. B – D Immunofluorescence staining of the ovaries collected 6 and 24 h after the i.p. injection of PBS or CTX. Rabbit monoclonal antibodies H3K27me3 ( B ), H3K9me3 ( C ), and EZH2 ( D ) were detected using anti-rabbit IgG (red). TUNEL was probed with Alexa Fluor 488 (green). Cell nuclei were labeled with DAPI (blue). Scale bar, 100 μm. N = 6 ovaries from different mice per time point for each group. E Western blot results for EZH2, H3K27me3, and γH2AX levels in the negative control (NC) and 4-HC treatment groups. β-actin and H3 were blotted as loading controls. F Quantitative expression of Ezh2 in the siNC and si Ezh2 -1 + 2 + 3 groups. G Western blot results of EZH2, H3K27me3, and γH2AX levels in the siNC and si Ezh2 -1 + 2 + 3 groups. β-actin and H3 were blotted as loading controls. Data are the mean ± SD of at least three independent experiments. Statistical analyses were carried out using a two-tailed Student’s t -test; *** P < 0.001.

Article Snippet: To evaluate the direct role of CTX, the GCs were treated with 2.5 μM 4-HC (the in vitro active form of CTX, HY-117433; MedChemExpress, Monmouth Junction, NJ, USA).

Techniques: Western Blot, Immunofluorescence, Staining, Injection, Bioprocessing, TUNEL Assay, Labeling, Negative Control, Expressing, Two Tailed Test