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Image Search Results
Journal: Scientific reports
Article Title: Novel anticancer agent, SQAP, binds to focal adhesion kinase and modulates its activity.
doi: 10.1038/srep15136
Figure Lengend Snippet: Figure 3. SPR analysis of the binding between SQAP and target proteins. Sensorgrams obtained by SPR analysis of SQAP (left) and SQP (right) with the candidate proteins: (A) SCP-2 KD 15.6 ± 2.2 μ M, (B) MFE-2 KD 14.2 ± 1.79 μ M, (C) ADRM1 KD 9.65 ± 2.91 μ M, (D) HR23B, (E) FAK KD 3.24 ± 0.21 μ M. The candidate proteins were immobilized onto the surface of a CM5 sensor chip. A solution of SQAP or SQP at variable concentrations was injected to generate result binding responses (RU) recorded as a function of time (sec). The results were analyzed using BIA evaluation 4.1.
Article Snippet: The proteins were first immobilized on a CM5 sensor chip of the
Techniques: Binding Assay, Injection