2d Search Results


diary product  (Pro-Lab Diagnostics)
97
Pro-Lab Diagnostics diary product
Diary Product, supplied by Pro-Lab Diagnostics, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 97 stars, based on 1 article reviews
diary product - by Bioz Stars, 2026-03
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free unbound mhc class i peptide monomers  (Miltenyi Biotec)
95
Miltenyi Biotec free unbound mhc class i peptide monomers
Free Unbound Mhc Class I Peptide Monomers, supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 95 stars, based on 1 article reviews
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pdquest advanced software  (Bio-Rad)
96
Bio-Rad pdquest advanced software
Pdquest Advanced Software, supplied by Bio-Rad, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 96 stars, based on 1 article reviews
pdquest advanced software - by Bioz Stars, 2026-03
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krasg12d inhibitor  (Selleck Chemicals)
93
Selleck Chemicals krasg12d inhibitor
Fig. 1 Abnormal KRAS activation induced the overexpression of ITGA2 in pancreatic cancer cells. a ITGA2 is one of the KRAS up-regulated surfaceome in different pancreatic ductal adenocarcinoma (PDAC) cell lines (AK10965, AK192, AK196) [16]. b Cancer molecular expression profile data of cBioPortal, showing the expression of ITGA2 in wt-KRAS and mut-KRAS pancreatic cancer. c RT-PCR was used to determine the mRNA expression level of ITGA2 in PANC-1 and AsPC-1 cells treated with <t>KRASG12D</t> inhibitor (KRpep-2d, 10uM). GAPDH served as an internal reference and repeated in triplicates. ***P < 0.001. d Western blot analysis for determining the protein expression level of ITGA2 in the PANC-1 or AsPC-1 cells treated with KRASG12D inhibitor (KRpep-2d, 10uM). GAPDH served as an internal reference. e RT-PCR was used to determine the expression level of ITGA2 in PANC-1 and AsPC-1 cells treated with ERK 1/2 inhibitors (U0126, 10uM). GAPDH served as an internal reference and repeated in triplcates. ***P < 0.001. f Western blot analysis for detrmining the protein expression level of ITGA2 in the PANC-1 or AsPC-1 cells treated with ERK1/2 inhibitor (U0126, 10uM). GAPDH served as an internal reference. g RT-PCR was used to determine the expression level of ITGA2 in PANC-1 and AsPC-1 cells infected with KRASG12D plasmids. GAPDH served as an internal reference and repeated in triplcates. ***P < 0.001. h Western blot analysis for determining the protein expression level of ITGA2, ERK1/2, p-ERK1/2, KRAS in the PANC-1 or AsPC-1 cells infected with KRASG12D plasmids. GAPDH served as an internal reference
Krasg12d Inhibitor, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
krasg12d inhibitor - by Bioz Stars, 2026-03
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2d clean up kit  (Bio-Rad)
96
Bio-Rad 2d clean up kit
Fig. 1 Abnormal KRAS activation induced the overexpression of ITGA2 in pancreatic cancer cells. a ITGA2 is one of the KRAS up-regulated surfaceome in different pancreatic ductal adenocarcinoma (PDAC) cell lines (AK10965, AK192, AK196) [16]. b Cancer molecular expression profile data of cBioPortal, showing the expression of ITGA2 in wt-KRAS and mut-KRAS pancreatic cancer. c RT-PCR was used to determine the mRNA expression level of ITGA2 in PANC-1 and AsPC-1 cells treated with <t>KRASG12D</t> inhibitor (KRpep-2d, 10uM). GAPDH served as an internal reference and repeated in triplicates. ***P < 0.001. d Western blot analysis for determining the protein expression level of ITGA2 in the PANC-1 or AsPC-1 cells treated with KRASG12D inhibitor (KRpep-2d, 10uM). GAPDH served as an internal reference. e RT-PCR was used to determine the expression level of ITGA2 in PANC-1 and AsPC-1 cells treated with ERK 1/2 inhibitors (U0126, 10uM). GAPDH served as an internal reference and repeated in triplcates. ***P < 0.001. f Western blot analysis for detrmining the protein expression level of ITGA2 in the PANC-1 or AsPC-1 cells treated with ERK1/2 inhibitor (U0126, 10uM). GAPDH served as an internal reference. g RT-PCR was used to determine the expression level of ITGA2 in PANC-1 and AsPC-1 cells infected with KRASG12D plasmids. GAPDH served as an internal reference and repeated in triplcates. ***P < 0.001. h Western blot analysis for determining the protein expression level of ITGA2, ERK1/2, p-ERK1/2, KRAS in the PANC-1 or AsPC-1 cells infected with KRASG12D plasmids. GAPDH served as an internal reference
2d Clean Up Kit, supplied by Bio-Rad, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 96 stars, based on 1 article reviews
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2 d quant kit  (GE Healthcare)
94
GE Healthcare 2 d quant kit
Fig. 1 Abnormal KRAS activation induced the overexpression of ITGA2 in pancreatic cancer cells. a ITGA2 is one of the KRAS up-regulated surfaceome in different pancreatic ductal adenocarcinoma (PDAC) cell lines (AK10965, AK192, AK196) [16]. b Cancer molecular expression profile data of cBioPortal, showing the expression of ITGA2 in wt-KRAS and mut-KRAS pancreatic cancer. c RT-PCR was used to determine the mRNA expression level of ITGA2 in PANC-1 and AsPC-1 cells treated with <t>KRASG12D</t> inhibitor (KRpep-2d, 10uM). GAPDH served as an internal reference and repeated in triplicates. ***P < 0.001. d Western blot analysis for determining the protein expression level of ITGA2 in the PANC-1 or AsPC-1 cells treated with KRASG12D inhibitor (KRpep-2d, 10uM). GAPDH served as an internal reference. e RT-PCR was used to determine the expression level of ITGA2 in PANC-1 and AsPC-1 cells treated with ERK 1/2 inhibitors (U0126, 10uM). GAPDH served as an internal reference and repeated in triplcates. ***P < 0.001. f Western blot analysis for detrmining the protein expression level of ITGA2 in the PANC-1 or AsPC-1 cells treated with ERK1/2 inhibitor (U0126, 10uM). GAPDH served as an internal reference. g RT-PCR was used to determine the expression level of ITGA2 in PANC-1 and AsPC-1 cells infected with KRASG12D plasmids. GAPDH served as an internal reference and repeated in triplcates. ***P < 0.001. h Western blot analysis for determining the protein expression level of ITGA2, ERK1/2, p-ERK1/2, KRAS in the PANC-1 or AsPC-1 cells infected with KRASG12D plasmids. GAPDH served as an internal reference
2 D Quant Kit, supplied by GE Healthcare, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/2 d quant kit/product/GE Healthcare
Average 94 stars, based on 1 article reviews
2 d quant kit - by Bioz Stars, 2026-03
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2 d clean up kit  (Danaher Inc)
94
Danaher Inc 2 d clean up kit
Fig. 1 Abnormal KRAS activation induced the overexpression of ITGA2 in pancreatic cancer cells. a ITGA2 is one of the KRAS up-regulated surfaceome in different pancreatic ductal adenocarcinoma (PDAC) cell lines (AK10965, AK192, AK196) [16]. b Cancer molecular expression profile data of cBioPortal, showing the expression of ITGA2 in wt-KRAS and mut-KRAS pancreatic cancer. c RT-PCR was used to determine the mRNA expression level of ITGA2 in PANC-1 and AsPC-1 cells treated with <t>KRASG12D</t> inhibitor (KRpep-2d, 10uM). GAPDH served as an internal reference and repeated in triplicates. ***P < 0.001. d Western blot analysis for determining the protein expression level of ITGA2 in the PANC-1 or AsPC-1 cells treated with KRASG12D inhibitor (KRpep-2d, 10uM). GAPDH served as an internal reference. e RT-PCR was used to determine the expression level of ITGA2 in PANC-1 and AsPC-1 cells treated with ERK 1/2 inhibitors (U0126, 10uM). GAPDH served as an internal reference and repeated in triplcates. ***P < 0.001. f Western blot analysis for detrmining the protein expression level of ITGA2 in the PANC-1 or AsPC-1 cells treated with ERK1/2 inhibitor (U0126, 10uM). GAPDH served as an internal reference. g RT-PCR was used to determine the expression level of ITGA2 in PANC-1 and AsPC-1 cells infected with KRASG12D plasmids. GAPDH served as an internal reference and repeated in triplcates. ***P < 0.001. h Western blot analysis for determining the protein expression level of ITGA2, ERK1/2, p-ERK1/2, KRAS in the PANC-1 or AsPC-1 cells infected with KRASG12D plasmids. GAPDH served as an internal reference
2 D Clean Up Kit, supplied by Danaher Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/2 d clean up kit/product/Danaher Inc
Average 94 stars, based on 1 article reviews
2 d clean up kit - by Bioz Stars, 2026-03
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mini protean 3 cell  (Bio-Rad)
96
Bio-Rad mini protean 3 cell
Fig. 1 Abnormal KRAS activation induced the overexpression of ITGA2 in pancreatic cancer cells. a ITGA2 is one of the KRAS up-regulated surfaceome in different pancreatic ductal adenocarcinoma (PDAC) cell lines (AK10965, AK192, AK196) [16]. b Cancer molecular expression profile data of cBioPortal, showing the expression of ITGA2 in wt-KRAS and mut-KRAS pancreatic cancer. c RT-PCR was used to determine the mRNA expression level of ITGA2 in PANC-1 and AsPC-1 cells treated with <t>KRASG12D</t> inhibitor (KRpep-2d, 10uM). GAPDH served as an internal reference and repeated in triplicates. ***P < 0.001. d Western blot analysis for determining the protein expression level of ITGA2 in the PANC-1 or AsPC-1 cells treated with KRASG12D inhibitor (KRpep-2d, 10uM). GAPDH served as an internal reference. e RT-PCR was used to determine the expression level of ITGA2 in PANC-1 and AsPC-1 cells treated with ERK 1/2 inhibitors (U0126, 10uM). GAPDH served as an internal reference and repeated in triplcates. ***P < 0.001. f Western blot analysis for detrmining the protein expression level of ITGA2 in the PANC-1 or AsPC-1 cells treated with ERK1/2 inhibitor (U0126, 10uM). GAPDH served as an internal reference. g RT-PCR was used to determine the expression level of ITGA2 in PANC-1 and AsPC-1 cells infected with KRASG12D plasmids. GAPDH served as an internal reference and repeated in triplcates. ***P < 0.001. h Western blot analysis for determining the protein expression level of ITGA2, ERK1/2, p-ERK1/2, KRAS in the PANC-1 or AsPC-1 cells infected with KRASG12D plasmids. GAPDH served as an internal reference
Mini Protean 3 Cell, supplied by Bio-Rad, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 96 stars, based on 1 article reviews
mini protean 3 cell - by Bioz Stars, 2026-03
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matrix 2d barcoded polypropylene storage tubes  (Thermo Fisher)
95
Thermo Fisher matrix 2d barcoded polypropylene storage tubes
Fig. 1 Abnormal KRAS activation induced the overexpression of ITGA2 in pancreatic cancer cells. a ITGA2 is one of the KRAS up-regulated surfaceome in different pancreatic ductal adenocarcinoma (PDAC) cell lines (AK10965, AK192, AK196) [16]. b Cancer molecular expression profile data of cBioPortal, showing the expression of ITGA2 in wt-KRAS and mut-KRAS pancreatic cancer. c RT-PCR was used to determine the mRNA expression level of ITGA2 in PANC-1 and AsPC-1 cells treated with <t>KRASG12D</t> inhibitor (KRpep-2d, 10uM). GAPDH served as an internal reference and repeated in triplicates. ***P < 0.001. d Western blot analysis for determining the protein expression level of ITGA2 in the PANC-1 or AsPC-1 cells treated with KRASG12D inhibitor (KRpep-2d, 10uM). GAPDH served as an internal reference. e RT-PCR was used to determine the expression level of ITGA2 in PANC-1 and AsPC-1 cells treated with ERK 1/2 inhibitors (U0126, 10uM). GAPDH served as an internal reference and repeated in triplcates. ***P < 0.001. f Western blot analysis for detrmining the protein expression level of ITGA2 in the PANC-1 or AsPC-1 cells treated with ERK1/2 inhibitor (U0126, 10uM). GAPDH served as an internal reference. g RT-PCR was used to determine the expression level of ITGA2 in PANC-1 and AsPC-1 cells infected with KRASG12D plasmids. GAPDH served as an internal reference and repeated in triplcates. ***P < 0.001. h Western blot analysis for determining the protein expression level of ITGA2, ERK1/2, p-ERK1/2, KRAS in the PANC-1 or AsPC-1 cells infected with KRASG12D plasmids. GAPDH served as an internal reference
Matrix 2d Barcoded Polypropylene Storage Tubes, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 95 stars, based on 1 article reviews
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2d protein extraction buffer v  (GE Healthcare)
91
GE Healthcare 2d protein extraction buffer v
Fig. 1 Abnormal KRAS activation induced the overexpression of ITGA2 in pancreatic cancer cells. a ITGA2 is one of the KRAS up-regulated surfaceome in different pancreatic ductal adenocarcinoma (PDAC) cell lines (AK10965, AK192, AK196) [16]. b Cancer molecular expression profile data of cBioPortal, showing the expression of ITGA2 in wt-KRAS and mut-KRAS pancreatic cancer. c RT-PCR was used to determine the mRNA expression level of ITGA2 in PANC-1 and AsPC-1 cells treated with <t>KRASG12D</t> inhibitor (KRpep-2d, 10uM). GAPDH served as an internal reference and repeated in triplicates. ***P < 0.001. d Western blot analysis for determining the protein expression level of ITGA2 in the PANC-1 or AsPC-1 cells treated with KRASG12D inhibitor (KRpep-2d, 10uM). GAPDH served as an internal reference. e RT-PCR was used to determine the expression level of ITGA2 in PANC-1 and AsPC-1 cells treated with ERK 1/2 inhibitors (U0126, 10uM). GAPDH served as an internal reference and repeated in triplcates. ***P < 0.001. f Western blot analysis for detrmining the protein expression level of ITGA2 in the PANC-1 or AsPC-1 cells treated with ERK1/2 inhibitor (U0126, 10uM). GAPDH served as an internal reference. g RT-PCR was used to determine the expression level of ITGA2 in PANC-1 and AsPC-1 cells infected with KRASG12D plasmids. GAPDH served as an internal reference and repeated in triplcates. ***P < 0.001. h Western blot analysis for determining the protein expression level of ITGA2, ERK1/2, p-ERK1/2, KRAS in the PANC-1 or AsPC-1 cells infected with KRASG12D plasmids. GAPDH served as an internal reference
2d Protein Extraction Buffer V, supplied by GE Healthcare, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 91 stars, based on 1 article reviews
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peroxiredoxin 5  (Proteintech)
93
Proteintech peroxiredoxin 5
Fig. 1 Abnormal KRAS activation induced the overexpression of ITGA2 in pancreatic cancer cells. a ITGA2 is one of the KRAS up-regulated surfaceome in different pancreatic ductal adenocarcinoma (PDAC) cell lines (AK10965, AK192, AK196) [16]. b Cancer molecular expression profile data of cBioPortal, showing the expression of ITGA2 in wt-KRAS and mut-KRAS pancreatic cancer. c RT-PCR was used to determine the mRNA expression level of ITGA2 in PANC-1 and AsPC-1 cells treated with <t>KRASG12D</t> inhibitor (KRpep-2d, 10uM). GAPDH served as an internal reference and repeated in triplicates. ***P < 0.001. d Western blot analysis for determining the protein expression level of ITGA2 in the PANC-1 or AsPC-1 cells treated with KRASG12D inhibitor (KRpep-2d, 10uM). GAPDH served as an internal reference. e RT-PCR was used to determine the expression level of ITGA2 in PANC-1 and AsPC-1 cells treated with ERK 1/2 inhibitors (U0126, 10uM). GAPDH served as an internal reference and repeated in triplcates. ***P < 0.001. f Western blot analysis for detrmining the protein expression level of ITGA2 in the PANC-1 or AsPC-1 cells treated with ERK1/2 inhibitor (U0126, 10uM). GAPDH served as an internal reference. g RT-PCR was used to determine the expression level of ITGA2 in PANC-1 and AsPC-1 cells infected with KRASG12D plasmids. GAPDH served as an internal reference and repeated in triplcates. ***P < 0.001. h Western blot analysis for determining the protein expression level of ITGA2, ERK1/2, p-ERK1/2, KRAS in the PANC-1 or AsPC-1 cells infected with KRASG12D plasmids. GAPDH served as an internal reference
Peroxiredoxin 5, supplied by Proteintech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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phenylpyridine  (Chem Impex International)
95
Chem Impex International phenylpyridine
Fig. 1 Abnormal KRAS activation induced the overexpression of ITGA2 in pancreatic cancer cells. a ITGA2 is one of the KRAS up-regulated surfaceome in different pancreatic ductal adenocarcinoma (PDAC) cell lines (AK10965, AK192, AK196) [16]. b Cancer molecular expression profile data of cBioPortal, showing the expression of ITGA2 in wt-KRAS and mut-KRAS pancreatic cancer. c RT-PCR was used to determine the mRNA expression level of ITGA2 in PANC-1 and AsPC-1 cells treated with <t>KRASG12D</t> inhibitor (KRpep-2d, 10uM). GAPDH served as an internal reference and repeated in triplicates. ***P < 0.001. d Western blot analysis for determining the protein expression level of ITGA2 in the PANC-1 or AsPC-1 cells treated with KRASG12D inhibitor (KRpep-2d, 10uM). GAPDH served as an internal reference. e RT-PCR was used to determine the expression level of ITGA2 in PANC-1 and AsPC-1 cells treated with ERK 1/2 inhibitors (U0126, 10uM). GAPDH served as an internal reference and repeated in triplcates. ***P < 0.001. f Western blot analysis for detrmining the protein expression level of ITGA2 in the PANC-1 or AsPC-1 cells treated with ERK1/2 inhibitor (U0126, 10uM). GAPDH served as an internal reference. g RT-PCR was used to determine the expression level of ITGA2 in PANC-1 and AsPC-1 cells infected with KRASG12D plasmids. GAPDH served as an internal reference and repeated in triplcates. ***P < 0.001. h Western blot analysis for determining the protein expression level of ITGA2, ERK1/2, p-ERK1/2, KRAS in the PANC-1 or AsPC-1 cells infected with KRASG12D plasmids. GAPDH served as an internal reference
Phenylpyridine, supplied by Chem Impex International, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 95 stars, based on 1 article reviews
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Image Search Results


Fig. 1 Abnormal KRAS activation induced the overexpression of ITGA2 in pancreatic cancer cells. a ITGA2 is one of the KRAS up-regulated surfaceome in different pancreatic ductal adenocarcinoma (PDAC) cell lines (AK10965, AK192, AK196) [16]. b Cancer molecular expression profile data of cBioPortal, showing the expression of ITGA2 in wt-KRAS and mut-KRAS pancreatic cancer. c RT-PCR was used to determine the mRNA expression level of ITGA2 in PANC-1 and AsPC-1 cells treated with KRASG12D inhibitor (KRpep-2d, 10uM). GAPDH served as an internal reference and repeated in triplicates. ***P < 0.001. d Western blot analysis for determining the protein expression level of ITGA2 in the PANC-1 or AsPC-1 cells treated with KRASG12D inhibitor (KRpep-2d, 10uM). GAPDH served as an internal reference. e RT-PCR was used to determine the expression level of ITGA2 in PANC-1 and AsPC-1 cells treated with ERK 1/2 inhibitors (U0126, 10uM). GAPDH served as an internal reference and repeated in triplcates. ***P < 0.001. f Western blot analysis for detrmining the protein expression level of ITGA2 in the PANC-1 or AsPC-1 cells treated with ERK1/2 inhibitor (U0126, 10uM). GAPDH served as an internal reference. g RT-PCR was used to determine the expression level of ITGA2 in PANC-1 and AsPC-1 cells infected with KRASG12D plasmids. GAPDH served as an internal reference and repeated in triplcates. ***P < 0.001. h Western blot analysis for determining the protein expression level of ITGA2, ERK1/2, p-ERK1/2, KRAS in the PANC-1 or AsPC-1 cells infected with KRASG12D plasmids. GAPDH served as an internal reference

Journal: Journal of experimental & clinical cancer research : CR

Article Title: Overexpressed integrin alpha 2 inhibits the activation of the transforming growth factor β pathway in pancreatic cancer via the TFCP2-SMAD2 axis.

doi: 10.1186/s13046-022-02286-5

Figure Lengend Snippet: Fig. 1 Abnormal KRAS activation induced the overexpression of ITGA2 in pancreatic cancer cells. a ITGA2 is one of the KRAS up-regulated surfaceome in different pancreatic ductal adenocarcinoma (PDAC) cell lines (AK10965, AK192, AK196) [16]. b Cancer molecular expression profile data of cBioPortal, showing the expression of ITGA2 in wt-KRAS and mut-KRAS pancreatic cancer. c RT-PCR was used to determine the mRNA expression level of ITGA2 in PANC-1 and AsPC-1 cells treated with KRASG12D inhibitor (KRpep-2d, 10uM). GAPDH served as an internal reference and repeated in triplicates. ***P < 0.001. d Western blot analysis for determining the protein expression level of ITGA2 in the PANC-1 or AsPC-1 cells treated with KRASG12D inhibitor (KRpep-2d, 10uM). GAPDH served as an internal reference. e RT-PCR was used to determine the expression level of ITGA2 in PANC-1 and AsPC-1 cells treated with ERK 1/2 inhibitors (U0126, 10uM). GAPDH served as an internal reference and repeated in triplcates. ***P < 0.001. f Western blot analysis for detrmining the protein expression level of ITGA2 in the PANC-1 or AsPC-1 cells treated with ERK1/2 inhibitor (U0126, 10uM). GAPDH served as an internal reference. g RT-PCR was used to determine the expression level of ITGA2 in PANC-1 and AsPC-1 cells infected with KRASG12D plasmids. GAPDH served as an internal reference and repeated in triplcates. ***P < 0.001. h Western blot analysis for determining the protein expression level of ITGA2, ERK1/2, p-ERK1/2, KRAS in the PANC-1 or AsPC-1 cells infected with KRASG12D plasmids. GAPDH served as an internal reference

Article Snippet: The antibodies for ITGA2 (#ab133557, Abcam, USA), GAPDH (#10494–1-AP, Proteintech, USA), TFCP2 (#15203-1-AP, Proteintech, USA), and SMAD2 (#13684S, Cell Signaling Technology, USA) and the recombinant proteins, including TGF-β (#ab50036; Abcam, USA), KRASG12D inhibitor (#S8499, SELLECK, USA), and U0126 (#HY-12031A; MedChemExpress, USA) recombinant proteins were purchased from the respective companies.

Techniques: Activation Assay, Over Expression, Expressing, Reverse Transcription Polymerase Chain Reaction, Western Blot, Infection