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Image Search Results
Journal: Frontiers in Microbiology
Article Title: Ketoconazole induces reversible antifungal drug tolerance mediated by trisomy of chromosome R in Candida albicans
doi: 10.3389/fmicb.2024.1450557
Figure Lengend Snippet: Cross-tolerance of aneuploids to different classes of antifungal drugs. The wild-type strain SC5314 and two strains bearing ChrR trisomy and tetrasomy, respectively, were evaluated for their tolerance to a range of antifungal drugs, including azoles (clotrimazole and miconazole), echinocandins (caspofungin), and pyrimidines (5-flucytosine). The concentrations of the drugs in the disks are depicted in the figure. The temperature used for testing was 37°C for 5-flucytosine and 30°C for the other drugs. The plates were incubated for 2 days before being photographed.
Article Snippet: KCZ (HY-B0105), NVP-HSP990 (HY-15190), Cyclosporin A (HY-B0579), caspofungin (HY-17006) and
Techniques: Incubation