2-mesadp Search Results


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Moravek Biochemicals 3 h]2mesadp
Binding affinities for different P2Y12R constructs. Affinity values of the agonist [ 3 <t> H]2MeSADP </t> determined in saturation binding to WT and mutant P2Y12Rs expressed transiently in COS7 cells (a) and inhibition by antagonist AZD1283 (b).
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Schattauer GmbH 2-mesadp
Binding affinities for different P2Y12R constructs. Affinity values of the agonist [ 3 <t> H]2MeSADP </t> determined in saturation binding to WT and mutant P2Y12Rs expressed transiently in COS7 cells (a) and inhibition by antagonist AZD1283 (b).
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Biotrend Chemicals 2-mesadp
Binding affinities for different P2Y12R constructs. Affinity values of the agonist [ 3 <t> H]2MeSADP </t> determined in saturation binding to WT and mutant P2Y12Rs expressed transiently in COS7 cells (a) and inhibition by antagonist AZD1283 (b).
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Bioconnect Systems Inc 2 methylthio adenosine 5' diphosphate (2 mesadp
Binding affinities for different P2Y12R constructs. Affinity values of the agonist [ 3 <t> H]2MeSADP </t> determined in saturation binding to WT and mutant P2Y12Rs expressed transiently in COS7 cells (a) and inhibition by antagonist AZD1283 (b).
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Moravek Biochemicals 3h]2methyladenosine 5 -diphosphate [3h]2-mesadp
Binding affinities for different P2Y12R constructs. Affinity values of the agonist [ 3 <t> H]2MeSADP </t> determined in saturation binding to WT and mutant P2Y12Rs expressed transiently in COS7 cells (a) and inhibition by antagonist AZD1283 (b).
3h]2methyladenosine 5 Diphosphate [3h]2 Mesadp, supplied by Moravek Biochemicals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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NEN Life Science 33p]2mesadp
Binding affinities for different P2Y12R constructs. Affinity values of the agonist [ 3 <t> H]2MeSADP </t> determined in saturation binding to WT and mutant P2Y12Rs expressed transiently in COS7 cells (a) and inhibition by antagonist AZD1283 (b).
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Blackwell Science Ltd 33p]2mesadp binding sites
Binding affinities for different P2Y12R constructs. Affinity values of the agonist [ 3 <t> H]2MeSADP </t> determined in saturation binding to WT and mutant P2Y12Rs expressed transiently in COS7 cells (a) and inhibition by antagonist AZD1283 (b).
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Takeda 2-mesadp
Binding affinities for different P2Y12R constructs. Affinity values of the agonist [ 3 <t> H]2MeSADP </t> determined in saturation binding to WT and mutant P2Y12Rs expressed transiently in COS7 cells (a) and inhibition by antagonist AZD1283 (b).
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Cayman Chemical 2-methylthioadenosine diphosphate 2mesadp
Binding affinities for different P2Y12R constructs. Affinity values of the agonist [ 3 <t> H]2MeSADP </t> determined in saturation binding to WT and mutant P2Y12Rs expressed transiently in COS7 cells (a) and inhibition by antagonist AZD1283 (b).
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Binding affinities for different P2Y12R constructs. Affinity values of the agonist [ 3  H]2MeSADP  determined in saturation binding to WT and mutant P2Y12Rs expressed transiently in COS7 cells (a) and inhibition by antagonist AZD1283 (b).

Journal: Nature

Article Title: Agonist-bound structure of the human P2Y 12 receptor

doi: 10.1038/nature13288

Figure Lengend Snippet: Binding affinities for different P2Y12R constructs. Affinity values of the agonist [ 3 H]2MeSADP determined in saturation binding to WT and mutant P2Y12Rs expressed transiently in COS7 cells (a) and inhibition by antagonist AZD1283 (b).

Article Snippet: For saturation experiments, 50 μl [ 3 H]2MeSADP (3.5 Ci/mmol, from 0.4 to 46 nM, Moravek, Brea, CA, USA) was incubated with 100 μl WT and mutant P2Y 12 R membrane preparations (5 μg/tube) in a total assay volume of 200 μl Tris·HCl buffer containing 10 mM MgCl 2 .

Techniques: Binding Assay, Construct, Mutagenesis, Inhibition