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Image Search Results
Journal: Journal of Translational Medicine
Article Title: Formyl peptide receptor 2 activation by MR-39 inhibits glioblastoma cell proliferation and invasiveness through suppression of multiple oncogenic pathways
doi: 10.1186/s12967-026-07781-3
Figure Lengend Snippet: Antiproliferative effect of MR-39 on human glioblastoma cell lines. ( A ) U87-MG, U138-MG, and U251-MG cells were exposed to 5-100 µM of MR-39 for 48 h. ( B ) Number of U87-MG, U138MG, and U251-MG cells exposed for 48 h to either the vehicle (CTRL) or 10 µM MR-39. ( C ) U87-MG, U138-MG, and U251-MG cells were exposed to either vehicle (CTRL) or 10 µM MR-39, with or without the FPR2 antagonist WRW4 (10 µM). ( D ) U87-MG cells were transfected with FPR2-targeting antisense siRNA1 or a negative control (siRNA-), followed by treatment with or without 10 µM MR-39. Cell proliferation was measured using the CCK-8 assay and is expressed as a percentage of the control. Data are expressed as means ± SEM, n = 3. Statistically significant differences are based on an unpaired t-test * p value < 0.05, ** p value < 0.005, *** p value < 0.001, **** p value < 0.0001 or one-way ANOVA followed by Tukey’s multiple comparison test
Article Snippet: EA.hy926 (CRL-2922 TM) andU87-MG (HTB-14 TM) cell lines were acquired from
Techniques: Transfection, Negative Control, CCK-8 Assay, Control, Comparison