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u138mg  (ATCC)
96
ATCC u138mg
Antiproliferative effect of MR-39 on human glioblastoma cell lines. ( A ) U87-MG, U138-MG, and U251-MG cells were exposed to 5-100 µM of MR-39 for 48 h. ( B ) Number of U87-MG, <t>U138MG,</t> and U251-MG cells exposed for 48 h to either the vehicle (CTRL) or 10 µM MR-39. ( C ) U87-MG, U138-MG, and U251-MG cells were exposed to either vehicle (CTRL) or 10 µM MR-39, with or without the FPR2 antagonist WRW4 (10 µM). ( D ) U87-MG cells were transfected with FPR2-targeting antisense siRNA1 or a negative control (siRNA-), followed by treatment with or without 10 µM MR-39. Cell proliferation was measured using the CCK-8 assay and is expressed as a percentage of the control. Data are expressed as means ± SEM, n = 3. Statistically significant differences are based on an unpaired t-test * p value < 0.05, ** p value < 0.005, *** p value < 0.001, **** p value < 0.0001 or one-way ANOVA followed by Tukey’s multiple comparison test
U138mg, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Digitimer North America LLC valvelink8 2 automatic solution changer
Antiproliferative effect of MR-39 on human glioblastoma cell lines. ( A ) U87-MG, U138-MG, and U251-MG cells were exposed to 5-100 µM of MR-39 for 48 h. ( B ) Number of U87-MG, <t>U138MG,</t> and U251-MG cells exposed for 48 h to either the vehicle (CTRL) or 10 µM MR-39. ( C ) U87-MG, U138-MG, and U251-MG cells were exposed to either vehicle (CTRL) or 10 µM MR-39, with or without the FPR2 antagonist WRW4 (10 µM). ( D ) U87-MG cells were transfected with FPR2-targeting antisense siRNA1 or a negative control (siRNA-), followed by treatment with or without 10 µM MR-39. Cell proliferation was measured using the CCK-8 assay and is expressed as a percentage of the control. Data are expressed as means ± SEM, n = 3. Statistically significant differences are based on an unpaired t-test * p value < 0.05, ** p value < 0.005, *** p value < 0.001, **** p value < 0.0001 or one-way ANOVA followed by Tukey’s multiple comparison test
Valvelink8 2 Automatic Solution Changer, supplied by Digitimer North America LLC, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Antiproliferative effect of MR-39 on human glioblastoma cell lines. ( A ) U87-MG, U138-MG, and U251-MG cells were exposed to 5-100 µM of MR-39 for 48 h. ( B ) Number of U87-MG, <t>U138MG,</t> and U251-MG cells exposed for 48 h to either the vehicle (CTRL) or 10 µM MR-39. ( C ) U87-MG, U138-MG, and U251-MG cells were exposed to either vehicle (CTRL) or 10 µM MR-39, with or without the FPR2 antagonist WRW4 (10 µM). ( D ) U87-MG cells were transfected with FPR2-targeting antisense siRNA1 or a negative control (siRNA-), followed by treatment with or without 10 µM MR-39. Cell proliferation was measured using the CCK-8 assay and is expressed as a percentage of the control. Data are expressed as means ± SEM, n = 3. Statistically significant differences are based on an unpaired t-test * p value < 0.05, ** p value < 0.005, *** p value < 0.001, **** p value < 0.0001 or one-way ANOVA followed by Tukey’s multiple comparison test
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Antiproliferative effect of MR-39 on human glioblastoma cell lines. ( A ) U87-MG, U138-MG, and U251-MG cells were exposed to 5-100 µM of MR-39 for 48 h. ( B ) Number of U87-MG, <t>U138MG,</t> and U251-MG cells exposed for 48 h to either the vehicle (CTRL) or 10 µM MR-39. ( C ) U87-MG, U138-MG, and U251-MG cells were exposed to either vehicle (CTRL) or 10 µM MR-39, with or without the FPR2 antagonist WRW4 (10 µM). ( D ) U87-MG cells were transfected with FPR2-targeting antisense siRNA1 or a negative control (siRNA-), followed by treatment with or without 10 µM MR-39. Cell proliferation was measured using the CCK-8 assay and is expressed as a percentage of the control. Data are expressed as means ± SEM, n = 3. Statistically significant differences are based on an unpaired t-test * p value < 0.05, ** p value < 0.005, *** p value < 0.001, **** p value < 0.0001 or one-way ANOVA followed by Tukey’s multiple comparison test
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Antiproliferative effect of MR-39 on human glioblastoma cell lines. ( A ) U87-MG, U138-MG, and U251-MG cells were exposed to 5-100 µM of MR-39 for 48 h. ( B ) Number of U87-MG, <t>U138MG,</t> and U251-MG cells exposed for 48 h to either the vehicle (CTRL) or 10 µM MR-39. ( C ) U87-MG, U138-MG, and U251-MG cells were exposed to either vehicle (CTRL) or 10 µM MR-39, with or without the FPR2 antagonist WRW4 (10 µM). ( D ) U87-MG cells were transfected with FPR2-targeting antisense siRNA1 or a negative control (siRNA-), followed by treatment with or without 10 µM MR-39. Cell proliferation was measured using the CCK-8 assay and is expressed as a percentage of the control. Data are expressed as means ± SEM, n = 3. Statistically significant differences are based on an unpaired t-test * p value < 0.05, ** p value < 0.005, *** p value < 0.001, **** p value < 0.0001 or one-way ANOVA followed by Tukey’s multiple comparison test
Dphpc, supplied by Croda International Plc, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Antiproliferative effect of MR-39 on human glioblastoma cell lines. ( A ) U87-MG, U138-MG, and U251-MG cells were exposed to 5-100 µM of MR-39 for 48 h. ( B ) Number of U87-MG, <t>U138MG,</t> and U251-MG cells exposed for 48 h to either the vehicle (CTRL) or 10 µM MR-39. ( C ) U87-MG, U138-MG, and U251-MG cells were exposed to either vehicle (CTRL) or 10 µM MR-39, with or without the FPR2 antagonist WRW4 (10 µM). ( D ) U87-MG cells were transfected with FPR2-targeting antisense siRNA1 or a negative control (siRNA-), followed by treatment with or without 10 µM MR-39. Cell proliferation was measured using the CCK-8 assay and is expressed as a percentage of the control. Data are expressed as means ± SEM, n = 3. Statistically significant differences are based on an unpaired t-test * p value < 0.05, ** p value < 0.005, *** p value < 0.001, **** p value < 0.0001 or one-way ANOVA followed by Tukey’s multiple comparison test
Liposomes, supplied by Croda International Plc, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Croda International Plc palmitoyl
Antiproliferative effect of MR-39 on human glioblastoma cell lines. ( A ) U87-MG, U138-MG, and U251-MG cells were exposed to 5-100 µM of MR-39 for 48 h. ( B ) Number of U87-MG, <t>U138MG,</t> and U251-MG cells exposed for 48 h to either the vehicle (CTRL) or 10 µM MR-39. ( C ) U87-MG, U138-MG, and U251-MG cells were exposed to either vehicle (CTRL) or 10 µM MR-39, with or without the FPR2 antagonist WRW4 (10 µM). ( D ) U87-MG cells were transfected with FPR2-targeting antisense siRNA1 or a negative control (siRNA-), followed by treatment with or without 10 µM MR-39. Cell proliferation was measured using the CCK-8 assay and is expressed as a percentage of the control. Data are expressed as means ± SEM, n = 3. Statistically significant differences are based on an unpaired t-test * p value < 0.05, ** p value < 0.005, *** p value < 0.001, **** p value < 0.0001 or one-way ANOVA followed by Tukey’s multiple comparison test
Palmitoyl, supplied by Croda International Plc, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Croda International Plc sodium salt avanti 870277 powder add chloroform to get 10 mg ml
Antiproliferative effect of MR-39 on human glioblastoma cell lines. ( A ) U87-MG, U138-MG, and U251-MG cells were exposed to 5-100 µM of MR-39 for 48 h. ( B ) Number of U87-MG, <t>U138MG,</t> and U251-MG cells exposed for 48 h to either the vehicle (CTRL) or 10 µM MR-39. ( C ) U87-MG, U138-MG, and U251-MG cells were exposed to either vehicle (CTRL) or 10 µM MR-39, with or without the FPR2 antagonist WRW4 (10 µM). ( D ) U87-MG cells were transfected with FPR2-targeting antisense siRNA1 or a negative control (siRNA-), followed by treatment with or without 10 µM MR-39. Cell proliferation was measured using the CCK-8 assay and is expressed as a percentage of the control. Data are expressed as means ± SEM, n = 3. Statistically significant differences are based on an unpaired t-test * p value < 0.05, ** p value < 0.005, *** p value < 0.001, **** p value < 0.0001 or one-way ANOVA followed by Tukey’s multiple comparison test
Sodium Salt Avanti 870277 Powder Add Chloroform To Get 10 Mg Ml, supplied by Croda International Plc, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Antiproliferative effect of MR-39 on human glioblastoma cell lines. ( A ) U87-MG, U138-MG, and U251-MG cells were exposed to 5-100 µM of MR-39 for 48 h. ( B ) Number of U87-MG, <t>U138MG,</t> and U251-MG cells exposed for 48 h to either the vehicle (CTRL) or 10 µM MR-39. ( C ) U87-MG, U138-MG, and U251-MG cells were exposed to either vehicle (CTRL) or 10 µM MR-39, with or without the FPR2 antagonist WRW4 (10 µM). ( D ) U87-MG cells were transfected with FPR2-targeting antisense siRNA1 or a negative control (siRNA-), followed by treatment with or without 10 µM MR-39. Cell proliferation was measured using the CCK-8 assay and is expressed as a percentage of the control. Data are expressed as means ± SEM, n = 3. Statistically significant differences are based on an unpaired t-test * p value < 0.05, ** p value < 0.005, *** p value < 0.001, **** p value < 0.0001 or one-way ANOVA followed by Tukey’s multiple comparison test
Dpps, supplied by Croda International Plc, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Croda International Plc lipids 1 palmitoyl 2 oleoyl sn glycero 3 phosphatidylethanolamine pope
Antiproliferative effect of MR-39 on human glioblastoma cell lines. ( A ) U87-MG, U138-MG, and U251-MG cells were exposed to 5-100 µM of MR-39 for 48 h. ( B ) Number of U87-MG, <t>U138MG,</t> and U251-MG cells exposed for 48 h to either the vehicle (CTRL) or 10 µM MR-39. ( C ) U87-MG, U138-MG, and U251-MG cells were exposed to either vehicle (CTRL) or 10 µM MR-39, with or without the FPR2 antagonist WRW4 (10 µM). ( D ) U87-MG cells were transfected with FPR2-targeting antisense siRNA1 or a negative control (siRNA-), followed by treatment with or without 10 µM MR-39. Cell proliferation was measured using the CCK-8 assay and is expressed as a percentage of the control. Data are expressed as means ± SEM, n = 3. Statistically significant differences are based on an unpaired t-test * p value < 0.05, ** p value < 0.005, *** p value < 0.001, **** p value < 0.0001 or one-way ANOVA followed by Tukey’s multiple comparison test
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Croda International Plc materials 1 palmitoyl 2 oleoyl sn glycero 3 phospho
Antiproliferative effect of MR-39 on human glioblastoma cell lines. ( A ) U87-MG, U138-MG, and U251-MG cells were exposed to 5-100 µM of MR-39 for 48 h. ( B ) Number of U87-MG, <t>U138MG,</t> and U251-MG cells exposed for 48 h to either the vehicle (CTRL) or 10 µM MR-39. ( C ) U87-MG, U138-MG, and U251-MG cells were exposed to either vehicle (CTRL) or 10 µM MR-39, with or without the FPR2 antagonist WRW4 (10 µM). ( D ) U87-MG cells were transfected with FPR2-targeting antisense siRNA1 or a negative control (siRNA-), followed by treatment with or without 10 µM MR-39. Cell proliferation was measured using the CCK-8 assay and is expressed as a percentage of the control. Data are expressed as means ± SEM, n = 3. Statistically significant differences are based on an unpaired t-test * p value < 0.05, ** p value < 0.005, *** p value < 0.001, **** p value < 0.0001 or one-way ANOVA followed by Tukey’s multiple comparison test
Materials 1 Palmitoyl 2 Oleoyl Sn Glycero 3 Phospho, supplied by Croda International Plc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Antiproliferative effect of MR-39 on human glioblastoma cell lines. ( A ) U87-MG, U138-MG, and U251-MG cells were exposed to 5-100 µM of MR-39 for 48 h. ( B ) Number of U87-MG, <t>U138MG,</t> and U251-MG cells exposed for 48 h to either the vehicle (CTRL) or 10 µM MR-39. ( C ) U87-MG, U138-MG, and U251-MG cells were exposed to either vehicle (CTRL) or 10 µM MR-39, with or without the FPR2 antagonist WRW4 (10 µM). ( D ) U87-MG cells were transfected with FPR2-targeting antisense siRNA1 or a negative control (siRNA-), followed by treatment with or without 10 µM MR-39. Cell proliferation was measured using the CCK-8 assay and is expressed as a percentage of the control. Data are expressed as means ± SEM, n = 3. Statistically significant differences are based on an unpaired t-test * p value < 0.05, ** p value < 0.005, *** p value < 0.001, **** p value < 0.0001 or one-way ANOVA followed by Tukey’s multiple comparison test
Spin Labeled Lipids 1 Palmitoyl 2 Stearoyl 14 Doxyl Sn Glycero 3 Phosphocholine, supplied by Croda International Plc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Antiproliferative effect of MR-39 on human glioblastoma cell lines. ( A ) U87-MG, U138-MG, and U251-MG cells were exposed to 5-100 µM of MR-39 for 48 h. ( B ) Number of U87-MG, U138MG, and U251-MG cells exposed for 48 h to either the vehicle (CTRL) or 10 µM MR-39. ( C ) U87-MG, U138-MG, and U251-MG cells were exposed to either vehicle (CTRL) or 10 µM MR-39, with or without the FPR2 antagonist WRW4 (10 µM). ( D ) U87-MG cells were transfected with FPR2-targeting antisense siRNA1 or a negative control (siRNA-), followed by treatment with or without 10 µM MR-39. Cell proliferation was measured using the CCK-8 assay and is expressed as a percentage of the control. Data are expressed as means ± SEM, n = 3. Statistically significant differences are based on an unpaired t-test * p value < 0.05, ** p value < 0.005, *** p value < 0.001, **** p value < 0.0001 or one-way ANOVA followed by Tukey’s multiple comparison test

Journal: Journal of Translational Medicine

Article Title: Formyl peptide receptor 2 activation by MR-39 inhibits glioblastoma cell proliferation and invasiveness through suppression of multiple oncogenic pathways

doi: 10.1186/s12967-026-07781-3

Figure Lengend Snippet: Antiproliferative effect of MR-39 on human glioblastoma cell lines. ( A ) U87-MG, U138-MG, and U251-MG cells were exposed to 5-100 µM of MR-39 for 48 h. ( B ) Number of U87-MG, U138MG, and U251-MG cells exposed for 48 h to either the vehicle (CTRL) or 10 µM MR-39. ( C ) U87-MG, U138-MG, and U251-MG cells were exposed to either vehicle (CTRL) or 10 µM MR-39, with or without the FPR2 antagonist WRW4 (10 µM). ( D ) U87-MG cells were transfected with FPR2-targeting antisense siRNA1 or a negative control (siRNA-), followed by treatment with or without 10 µM MR-39. Cell proliferation was measured using the CCK-8 assay and is expressed as a percentage of the control. Data are expressed as means ± SEM, n = 3. Statistically significant differences are based on an unpaired t-test * p value < 0.05, ** p value < 0.005, *** p value < 0.001, **** p value < 0.0001 or one-way ANOVA followed by Tukey’s multiple comparison test

Article Snippet: EA.hy926 (CRL-2922 TM) andU87-MG (HTB-14 TM) cell lines were acquired from ATCC, while U138MG, and U251-MG were kindly provided by Prof. Generoso Luca Colucci D’Amato, University of Campania “Luigi Vanvitelli” [ ].

Techniques: Transfection, Negative Control, CCK-8 Assay, Control, Comparison