14058s Search Results


b7 h3  (Cell Signaling Technology Inc)
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Cell Signaling Technology Inc b7 h3
Correlation analyses between the risk scores, GRGs, and the immune checkpoint genes in HCC. ( A ) Differential expressions of immune checkpoint genes in high- and low-risk groups of HCC. ( B ) Correlation analyses between risk scores and the multiple immune checkpoint gene expressions in HCC. ( C ) Correlation analyses between the expressions of GRGs and immune checkpoint genes in HCC. ( D ) Correlation dot plots of ST6GALNAC4 with multiple immune checkpoint genes in HCC from the TIMER database. ( E ) Correlation dot plots of <t>B7-H3</t> with GRGs from the TIMER database.
B7 H3, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/14058s/B7-H3+XP+Rabbit+mAb/pmc10081533-107-10-15
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Correlation analyses between the risk scores, GRGs, and the immune checkpoint genes in HCC. ( A ) Differential expressions of immune checkpoint genes in high- and low-risk groups of HCC. ( B ) Correlation analyses between risk scores and the multiple immune checkpoint gene expressions in HCC. ( C ) Correlation analyses between the expressions of GRGs and immune checkpoint genes in HCC. ( D ) Correlation dot plots of ST6GALNAC4 with multiple immune checkpoint genes in HCC from the TIMER database. ( E ) Correlation dot plots of B7-H3 with GRGs from the TIMER database.

Journal: Journal of Hepatocellular Carcinoma

Article Title: Identification and Experimental Validation of the Prognostic Significance and Immunological Correlation of Glycosylation-Related Signature and ST6GALNAC4 in Hepatocellular Carcinoma

doi: 10.2147/JHC.S400472

Figure Lengend Snippet: Correlation analyses between the risk scores, GRGs, and the immune checkpoint genes in HCC. ( A ) Differential expressions of immune checkpoint genes in high- and low-risk groups of HCC. ( B ) Correlation analyses between risk scores and the multiple immune checkpoint gene expressions in HCC. ( C ) Correlation analyses between the expressions of GRGs and immune checkpoint genes in HCC. ( D ) Correlation dot plots of ST6GALNAC4 with multiple immune checkpoint genes in HCC from the TIMER database. ( E ) Correlation dot plots of B7-H3 with GRGs from the TIMER database.

Article Snippet: The antibodies for detection of GAPDH (5174), PD-L1 (13684), and B7-H3 (14058) were purchased from Cell Signaling Technology (Danvers, MA, USA).

Techniques:

Validation of ST6GALNAC4 expression in HCC tissues and its correlation with immune checkpoints. ( A ) Expression profile of ST6GALNAC4 in 47 HCC tissues compared to paracan-cerous tissues. ( B ) The mean expression level of ST6GALNAC4 in 47 paired HCC and paracan-cerous tissues (**p < 0.01). ( C ) The relative expression distribution of ST6GALNAC4, PD-L1, and B7-H3 in HCC tissues. ( D ) Correlation analyses of ST6GALNAC4 expression with PD-L1 and B7-H3 in HCC tissues. ( E ) Western blot analysis for ST6GALNAC4 protein expression in HCC and paracancerous tissues.

Journal: Journal of Hepatocellular Carcinoma

Article Title: Identification and Experimental Validation of the Prognostic Significance and Immunological Correlation of Glycosylation-Related Signature and ST6GALNAC4 in Hepatocellular Carcinoma

doi: 10.2147/JHC.S400472

Figure Lengend Snippet: Validation of ST6GALNAC4 expression in HCC tissues and its correlation with immune checkpoints. ( A ) Expression profile of ST6GALNAC4 in 47 HCC tissues compared to paracan-cerous tissues. ( B ) The mean expression level of ST6GALNAC4 in 47 paired HCC and paracan-cerous tissues (**p < 0.01). ( C ) The relative expression distribution of ST6GALNAC4, PD-L1, and B7-H3 in HCC tissues. ( D ) Correlation analyses of ST6GALNAC4 expression with PD-L1 and B7-H3 in HCC tissues. ( E ) Western blot analysis for ST6GALNAC4 protein expression in HCC and paracancerous tissues.

Article Snippet: The antibodies for detection of GAPDH (5174), PD-L1 (13684), and B7-H3 (14058) were purchased from Cell Signaling Technology (Danvers, MA, USA).

Techniques: Biomarker Discovery, Expressing, Western Blot

Effect of ST6GALNAC4 knockdown on hepatoma cells. ( A ) Expression of PD-L1 and B7-H3 mRNA in hepatoma cells after ST6GALNAC4 knockdown. ( B and C ) Flow cytometric and Western blot analyses of PD-L1 and B7-H3 expression in hepatoma cells after ST6GALNAC4 knockdown. ( D ) CCK-8 analysis of the effect of ST6GALNAC4 knockdown on the proliferative capacity of hepatoma cells. ( E and F ) Effect of ST6GALNAC4 knockdown on the clone formation ability and cell cycle of hepatoma cells. ( G and H ) ST6GALNAC4 knockdown inhibited the migration and invasion ability of hepatoma cells. ns not significant, *p < 0.05, **p < 0.01, ***p < 0.001.

Journal: Journal of Hepatocellular Carcinoma

Article Title: Identification and Experimental Validation of the Prognostic Significance and Immunological Correlation of Glycosylation-Related Signature and ST6GALNAC4 in Hepatocellular Carcinoma

doi: 10.2147/JHC.S400472

Figure Lengend Snippet: Effect of ST6GALNAC4 knockdown on hepatoma cells. ( A ) Expression of PD-L1 and B7-H3 mRNA in hepatoma cells after ST6GALNAC4 knockdown. ( B and C ) Flow cytometric and Western blot analyses of PD-L1 and B7-H3 expression in hepatoma cells after ST6GALNAC4 knockdown. ( D ) CCK-8 analysis of the effect of ST6GALNAC4 knockdown on the proliferative capacity of hepatoma cells. ( E and F ) Effect of ST6GALNAC4 knockdown on the clone formation ability and cell cycle of hepatoma cells. ( G and H ) ST6GALNAC4 knockdown inhibited the migration and invasion ability of hepatoma cells. ns not significant, *p < 0.05, **p < 0.01, ***p < 0.001.

Article Snippet: The antibodies for detection of GAPDH (5174), PD-L1 (13684), and B7-H3 (14058) were purchased from Cell Signaling Technology (Danvers, MA, USA).

Techniques: Knockdown, Expressing, Western Blot, CCK-8 Assay, Migration