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Image Search Results
Journal: Journal of immunology (Baltimore, Md. : 1950)
Article Title: Lymphotoxin Signaling is Essential for Clearance of Salmonella from the Gut Lumen and Generation of anti- Salmonella Protective Immunity
doi: 10.4049/jimmunol.1600867
Figure Lengend Snippet: Oral streptomycin was administered to Ltbr+/− and Ltbr−/− one day prior to oral administration of S. S. Tm A. Serum anti- S. Tm IgM as measured by ELISA. B. Serum anti- S. Tm IgG. A–B Ltbr+/− n = 12 Ltbr−/− n = 14, pooled from four independent experiments, each dot represents group mean, bars represent mean + SEM. C. Fecal anti-S. Tm IgA, one experiment Ltbr+/− n = 4 Ltbr−/− n = 6. D. 100µg LTβR-Ig was administered i.p. every 7 days starting at day 22 and ending on day 43 after oral administration of attenuated Salmonella to Ltbr+/− animals. Littermate Ltbr−/− and untreated Ltbr+/− are included as a positive control. Ltbr+/− n= 8, Ltbr+/−+ LTβR-Ig n = 9, Ltbr−/− n = 4, pooled from two independent experiments. For E splenocyte cultures were restimulated or not for 48 hours in vitro with S. Tm protein extract E. IFN-γ concentration in supernatant after 48 house, n = 3–8 per group pooled from three independent experiments. * P < 0.05, ** P < 0.01 by Mann-Whitney test.
Article Snippet: After washing, detection antibody for
Techniques: Enzyme-linked Immunosorbent Assay, Positive Control, In Vitro, Concentration Assay, MANN-WHITNEY
Journal: Journal of immunology (Baltimore, Md. : 1950)
Article Title: Lymphotoxin Signaling is Essential for Clearance of Salmonella from the Gut Lumen and Generation of anti- Salmonella Protective Immunity
doi: 10.4049/jimmunol.1600867
Figure Lengend Snippet: Oral streptomycin was administered to littermate mice one day prior to oral administration of S. Tmaten. 45 days later animals were challenged orally with S. Tmwt. A, B Ltb+/− and Ltb−/− mice. A. Serum anti-S. Tm IgG. B. Survival after challenge with virulent S. Tmwt. Ltb+/− n = 11, Ltb−/− n = 8, two pooled experiments. C, D Ltbfl/fl and RorcCre+ Ltbfl/fl mice. C. Anti- S. Tm IgG. D. Survival post challenge with S. Tmwt. Two pooled experiments. Ltbfl/fl n = 6, Rorccre+Ltbfl/fl n = 6. E, F Ltbfl/fl and Cd19Cre+ Ltbfl/fl mice. E. serum anti-S. Tm IgG. F. Survival post challenge with S. Tmwt. Ltbfl/fl n= 7, Cd19Cre+Ltbfl/fl n = 10. CFU and IgG statistics * P < 0.05, ** P < 0.01 by Mann-Whitney test. Survival statistics * P < 0.5, *** P < 0.001 by Mantel-Cox test.
Article Snippet: After washing, detection antibody for
Techniques: MANN-WHITNEY