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Image Search Results
Journal: Cell
Article Title: Multidimensional tracking of GPCR signaling via peroxidase-catalyzed proximity labeling
doi: 10.1016/j.cell.2017.03.028
Figure Lengend Snippet: (A) Internalization kinetics of β2AR (class A GPCR) are different from those of AT1R (class B GPCR). β-arrestin is recruited with the peak at 180 s, but clathrin recruitment is delayed to 600 s. Also, Rab5 enrichment peak is at 600 s, indicating arrestin-receptor complex formation and endosomal entry do not occur simultaneously. Late endosomal marker Rab7 and lysosomal marker LAMP1 enrichment peaks appear afterward.
Article Snippet: Each well was transfected with 20 ng each of a
Techniques: Marker