Journal: Journal of Pharmaceutical Health Care and Sciences

Article Title: Bisphosphonate compliance in Japan from the perspective of product, formulation, and patient characteristics: analysis of medical insurance claim data

doi: 10.1186/s40780-025-00434-5

Figure Lengend Snippet: Medical compliance by products (brand-name and major generic)

Article Snippet: Risedronate Tablet 17.5mg "Sawai" , RIS , [W] , 2288 , 77.2% (33.9%) , 67.3% , 6.8% , 26.0% , 4 , 2.

Techniques:

Journal: Medicina

Article Title: Tibial Insufficiency Fracture with Characteristics of an Atypical Fracture: A Rare Case and Literature Review

doi: 10.3390/medicina60111814

Figure Lengend Snippet: Current published case reports on atypical tibial fractures associated with long-term bisphosphonate/antiresorptive use.

Article Snippet: The patient had been taking the bisphosphonate sodium risedronate (Actonel ® ; Sanofi-Aventis, Paris, France) 150 mg orally once a month for 4 years for osteoporosis, followed by intravenous administration of the bisphosphonate ibandronate sodium monohydrate (Bonviva ® ; Roche, Basel, Switzerland) 3 mg every three months for the subsequent 10 years.

Techniques:

Journal: Biomedicines

Article Title: Influence of Metamizole on Antitumour Activity of Risedronate Sodium in In Vitro Studies on Canine (D-17) and Human (U-2 OS) Osteosarcoma Cell Lines

doi: 10.3390/biomedicines12081869

Figure Lengend Snippet: Drug concentrations used to estimate EC 50 value.

Article Snippet: Metamizole (meta) (Sigma-Aldrich, Taufkirchen, Germany) and risedronate sodium (rd) (Sigma-Aldrich, Taufkirchen, Germany) were dissolved in the culture media. presents the range of individual drug concentrations, selected based on their maximum serum concentration; in the case of both drugs, the type of solvent did not have a limiting effect on the selected concentrations.

Techniques: Concentration Assay

Journal: Biomedicines

Article Title: Influence of Metamizole on Antitumour Activity of Risedronate Sodium in In Vitro Studies on Canine (D-17) and Human (U-2 OS) Osteosarcoma Cell Lines

doi: 10.3390/biomedicines12081869

Figure Lengend Snippet: EC 50 values for the tested drugs.

Article Snippet: Metamizole (meta) (Sigma-Aldrich, Taufkirchen, Germany) and risedronate sodium (rd) (Sigma-Aldrich, Taufkirchen, Germany) were dissolved in the culture media. presents the range of individual drug concentrations, selected based on their maximum serum concentration; in the case of both drugs, the type of solvent did not have a limiting effect on the selected concentrations.

Techniques:

Journal: Biomedicines

Article Title: Influence of Metamizole on Antitumour Activity of Risedronate Sodium in In Vitro Studies on Canine (D-17) and Human (U-2 OS) Osteosarcoma Cell Lines

doi: 10.3390/biomedicines12081869

Figure Lengend Snippet: Combinations of metamizole and risedronate sodium used in the study.

Article Snippet: Metamizole (meta) (Sigma-Aldrich, Taufkirchen, Germany) and risedronate sodium (rd) (Sigma-Aldrich, Taufkirchen, Germany) were dissolved in the culture media. presents the range of individual drug concentrations, selected based on their maximum serum concentration; in the case of both drugs, the type of solvent did not have a limiting effect on the selected concentrations.

Techniques:

Journal: Biomedicines

Article Title: Influence of Metamizole on Antitumour Activity of Risedronate Sodium in In Vitro Studies on Canine (D-17) and Human (U-2 OS) Osteosarcoma Cell Lines

doi: 10.3390/biomedicines12081869

Figure Lengend Snippet: The effect of risedronate sodium and metamizole on cell viability of the D-17 canine and U-2 OS human osteosarcoma cell lines, * values below control in the Dunnett test.

Article Snippet: Metamizole (meta) (Sigma-Aldrich, Taufkirchen, Germany) and risedronate sodium (rd) (Sigma-Aldrich, Taufkirchen, Germany) were dissolved in the culture media. presents the range of individual drug concentrations, selected based on their maximum serum concentration; in the case of both drugs, the type of solvent did not have a limiting effect on the selected concentrations.

Techniques: Control

Journal: Biomedicines

Article Title: Influence of Metamizole on Antitumour Activity of Risedronate Sodium in In Vitro Studies on Canine (D-17) and Human (U-2 OS) Osteosarcoma Cell Lines

doi: 10.3390/biomedicines12081869

Figure Lengend Snippet: The effect of combinations of risedronate sodium and metamizole on cell viability in the canine D-17 and human U-2 OS osteosarcoma cell lines, * values below control in the Dunnett test.

Article Snippet: Metamizole (meta) (Sigma-Aldrich, Taufkirchen, Germany) and risedronate sodium (rd) (Sigma-Aldrich, Taufkirchen, Germany) were dissolved in the culture media. presents the range of individual drug concentrations, selected based on their maximum serum concentration; in the case of both drugs, the type of solvent did not have a limiting effect on the selected concentrations.

Techniques: Control

Journal: Biomedicines

Article Title: Influence of Metamizole on Antitumour Activity of Risedronate Sodium in In Vitro Studies on Canine (D-17) and Human (U-2 OS) Osteosarcoma Cell Lines

doi: 10.3390/biomedicines12081869

Figure Lengend Snippet: The effect of risedronate sodium and metamizole on apoptosis in the canine and human osteosarcoma cell lines, * values below control in the Dunnett test.

Article Snippet: Metamizole (meta) (Sigma-Aldrich, Taufkirchen, Germany) and risedronate sodium (rd) (Sigma-Aldrich, Taufkirchen, Germany) were dissolved in the culture media. presents the range of individual drug concentrations, selected based on their maximum serum concentration; in the case of both drugs, the type of solvent did not have a limiting effect on the selected concentrations.

Techniques: Control

Journal: Biomedicines

Article Title: Influence of Metamizole on Antitumour Activity of Risedronate Sodium in In Vitro Studies on Canine (D-17) and Human (U-2 OS) Osteosarcoma Cell Lines

doi: 10.3390/biomedicines12081869

Figure Lengend Snippet: The effect of risedronate sodium and metamizole combinations on apoptosis in the canine D-17 and human U-2 OS osteosarcoma cell lines.

Article Snippet: Metamizole (meta) (Sigma-Aldrich, Taufkirchen, Germany) and risedronate sodium (rd) (Sigma-Aldrich, Taufkirchen, Germany) were dissolved in the culture media. presents the range of individual drug concentrations, selected based on their maximum serum concentration; in the case of both drugs, the type of solvent did not have a limiting effect on the selected concentrations.

Techniques:

Journal: Biomedicines

Article Title: Influence of Metamizole on Antitumour Activity of Risedronate Sodium in In Vitro Studies on Canine (D-17) and Human (U-2 OS) Osteosarcoma Cell Lines

doi: 10.3390/biomedicines12081869

Figure Lengend Snippet: The effect of risedronate sodium and metamizole on the cell cycle in the canine osteosarcoma D-17 cell line, * values below control in the Dunnett test.

Article Snippet: Metamizole (meta) (Sigma-Aldrich, Taufkirchen, Germany) and risedronate sodium (rd) (Sigma-Aldrich, Taufkirchen, Germany) were dissolved in the culture media. presents the range of individual drug concentrations, selected based on their maximum serum concentration; in the case of both drugs, the type of solvent did not have a limiting effect on the selected concentrations.

Techniques: Control

Journal: Biomedicines

Article Title: Influence of Metamizole on Antitumour Activity of Risedronate Sodium in In Vitro Studies on Canine (D-17) and Human (U-2 OS) Osteosarcoma Cell Lines

doi: 10.3390/biomedicines12081869

Figure Lengend Snippet: The effect of risedronate sodium and metamizole on the cell cycle in the U-2 OS human osteosarcoma cell line, * values below control in the Dunnett test.

Article Snippet: Metamizole (meta) (Sigma-Aldrich, Taufkirchen, Germany) and risedronate sodium (rd) (Sigma-Aldrich, Taufkirchen, Germany) were dissolved in the culture media. presents the range of individual drug concentrations, selected based on their maximum serum concentration; in the case of both drugs, the type of solvent did not have a limiting effect on the selected concentrations.

Techniques: Control

Journal: Biomedicines

Article Title: Influence of Metamizole on Antitumour Activity of Risedronate Sodium in In Vitro Studies on Canine (D-17) and Human (U-2 OS) Osteosarcoma Cell Lines

doi: 10.3390/biomedicines12081869

Figure Lengend Snippet: The effect of combinations of risedronate sodium with metamizole on the cell cycle in the canine osteosarcoma D-17 cell line, * values below control in the Dunnett test.

Article Snippet: Metamizole (meta) (Sigma-Aldrich, Taufkirchen, Germany) and risedronate sodium (rd) (Sigma-Aldrich, Taufkirchen, Germany) were dissolved in the culture media. presents the range of individual drug concentrations, selected based on their maximum serum concentration; in the case of both drugs, the type of solvent did not have a limiting effect on the selected concentrations.

Techniques: Control

Journal: Biomedicines

Article Title: Influence of Metamizole on Antitumour Activity of Risedronate Sodium in In Vitro Studies on Canine (D-17) and Human (U-2 OS) Osteosarcoma Cell Lines

doi: 10.3390/biomedicines12081869

Figure Lengend Snippet: The effect of combinations of risedronate sodium with metamizole on the cell cycle in the U-2 OS human osteosarcoma cell line, * values below control in the Dunnett test.

Article Snippet: Metamizole (meta) (Sigma-Aldrich, Taufkirchen, Germany) and risedronate sodium (rd) (Sigma-Aldrich, Taufkirchen, Germany) were dissolved in the culture media. presents the range of individual drug concentrations, selected based on their maximum serum concentration; in the case of both drugs, the type of solvent did not have a limiting effect on the selected concentrations.

Techniques: Control